509 results
1-year SELUTION DeNovo results: drug-eluting balloon strategy vs. systematic drug-eluting stent in de novo coronary disease
29 Oct 2025
Guillaume Bonnet interviews Christian Spaulding about the SELUTION DeNovo Trial he presented at TCT 2025, in San Francisco.
Prof. Christian Spaulding, principal investigator of the study, discusses the trial design, key outcomes, breaks down the nuances behind the sirolimus DCB strategy versus contemporary DES, and shares insights...

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Validation of intravascular ultrasound-defined optimal stent expansion criteria for favorable 1-year clinical outcomes
17 Nov 2025
This individual patient data analysis of the three largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated with reduced TVF at one year.

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Reviewer
Ten trials from AHA 2025
12 Nov 2025
Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Author
ADAPT AF-DES: PCR Trials Book
19 Dec 2025
The PCR Trials Book provides updates on the latest randomised clinical trials of relevance to practicing interventional cardiologists in the field of coronary, valvular and structural interventions. Each trial, selected by the Editors, has been synthesised in order to provide you with a concise overview. View a...
1-year SELUTION DeNovo results: what they mean for daily practice
29 Oct 2025
The SELUTION DeNovo trial, presented by Christian Spaulding at TCT 2025, delivers the first head-to-head comparison between a sirolimus DCB strategy and contemporary DES in PCI.
In this review, Salvatore Brugaletta breaks down the 1-year results and what these findings truly mean for everyday lesion-by-lesion decision-making.

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Comparison of drug-coated versus conventional balloons for treatment of side branches of bifurcation lesions: the OCVC-BIF study
29 Oct 2025
Ali Nazmi Calik provides his take on the OCVC-BIF study presented by Takayuki Ishihara at TCT 2025, in San Francisco.

Author
Sirolimus-eluting iron bioresorbable scaffold in coronary artery disease: two-year results of IRONMAN-II randomised controlled trial
25 Oct 2025
Alex Sticchi interviews Lei Song on the IRONMAN II trial he presented at TCT 2025, in San Francisco.

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Author
New DCB indications for everyday practice
14 Oct 2025
Watch this replay with F. Ribichini, M. Götberg, B. Khialani and B. Vaquerizo to Review the newest indications for the use of DCB with a focus on STEMI, CTO, bifurcations and calcified lesions, and so much more!
Provisional stenting with a scaffold stent and DCB in calcified left main bifucation - LIVE Case
11 Oct 2025 – From AICT-AsiaPCR 2025
A 59-year-old male presented with CCS for three months, with diabetes and normal LV function (72%). Coronary angiography showed a calcified left main stenosis (Medina 1,1,1) and diffuse calcification of the proximal and mid LAD. The LCX QFR was 0.86.
Treatment included extensive lesion preparation with lithotripsy...
Bifurcations and left main interventions
11 Oct 2025 – From AICT-AsiaPCR 2025
Delve into the complexities of bifurcation and left main coronary interventions with this session focusing on challenging cases and advanced techniques. Topics include management of complications during drug-eluting stent deployment, Impella-supported orbital atherectomy in heavily calcified lesions, and PCI in patients with severe comorbidities such as...