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Left main and multivessel disease

Latest left main and multivessel disease content in interventional cardiology - research, practice, and education

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

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Physiological vs. anatomical assessment of multivessel disease patients

21 May 2026 – From EuroPCR 2026

This session delves into the comparative benefits of physiological versus anatomical assessment in patients with multivessel coronary disease, focusing particularly on myocardial infarction cases. Attendees will explore how coronary physiology can guide complete revascularisation, the added value of physiological assessment beyond conventional angiography, and the selection...

A new horizon in left main and multivessel PCI

21 May 2026 – From EuroPCR 2026

This session explores new horizons in managing left main and multivessel coronary artery disease with PCI. It covers comprehensive evaluation techniques, including physiology and imaging assessments, and advanced PCI strategies for challenging eccentric and heavily calcified lesions. Case presentations from diverse clinical contexts illustrate decision-making and...

Left main complications - Part 2

21 May 2026 – From EuroPCR 2026

This session covers intricate complications involving the left main coronary artery (LMCA), highlighting cases of catheter-induced dissections, challenges in chronic total occlusion (CTO) PCI, and rare scenarios such as stent entrapment and complex re-interventions. Emphasis is placed on the critical utility of intravascular ultrasound (IVUS) and...

Complex multivessel disease: from calcium to physiology - Case-based decisions

21 May 2026 – From EuroPCR 2026

Focus on complex multivessel coronary artery disease management with an emphasis on severely calcified lesions and the integration of intracoronary imaging and physiology. This session prepares clinicians to anticipate and manage complications during PCI, enhancing competence in treating challenging coronary anatomies through case-based decision-making.

Left main interventions: pushing the boundaries

21 May 2026 – From EuroPCR 2026

Examine contemporary strategies for distal left main bifurcation disease treatment, including debates on complex bifurcation and high-risk PCI approaches. The session emphasizes the critical role of coronary imaging in guiding decision-making and showcases clinical cases illustrating management of left main interventions under challenging conditions.

Challenges of multivessel disease in ACS

21 May 2026 – From EuroPCR 2026

Dedicated to the challenges of multivessel disease in acute coronary syndrome (ACS), this session explores strategies to identify culprit versus non-culprit lesions and plan multivessel revascularisation using physiology, intravascular imaging, and artificial intelligence. It further discusses the timing considerations for revascularisation, whether ad-hoc or staged, illustrated...

Multivessel complications: what can go wrong

21 May 2026 – From EuroPCR 2026

This session highlights complications encountered in multivessel coronary interventions, presenting complex cases such as lost stents, coronary perforations, shaft fractures, early subacute stent thrombosis, and rare triple vessel thrombosis. It emphasizes practical management strategies for these challenging scenarios in contemporary interventional cardiology.

Revascularisation in patients with multivessel disease and severe left ventricular impairment

21 May 2026 – From EuroPCR 2026

This session focuses on revascularisation strategies for patients with multivessel coronary disease complicated by severe left ventricular impairment. It emphasizes patient selection criteria, the crucial role of the heart team in decision-making, and optimization of percutaneous revascularisation outcomes. The content includes comprehensive case presentations and discussions...

Left main PCI: technical limits

21 May 2026 – From EuroPCR 2026

This comprehensive session reviews the technical challenges and current strategies in left main PCI. Topics include provisional versus DK crush approaches, IVUS-based assessment of ostial LAD lesions, long-term outcomes of DCB use in left main bifurcations, stenting strategies for complex lesions, and the prognostic value of...

Ambiguous left main lesions: how to assess severity and make the right decision

21 May 2026 – From EuroPCR 2026

Addressing the complexities of ambiguous left main coronary lesions, this session elucidates the integration of physiology, intracoronary imaging, and CT scanning for comprehensive assessment. It highlights multimodality diagnostic strategies and decision-making frameworks to guide appropriate revascularization.