Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

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First guidelines for the treatment of LM disease issued by SOLACI and SIAC

22 May 2025 – From EuroPCR 2025

During EuroPCR 2025, Cleverson Zukowski and Pablo Lamelas introduce a landmark initiative: the first clinical guidelines for left main disease specifically developed for Latin America.

Published by the Latin American Society of Interventional Cardiology (SOLACI) and the Interamerican Society of Cardiology (SIAC), these recommendations aim to support...

First guidelines for the treatment of LM disease issued by SOLACI and SIAC

How to manage treatment dilemmas in STEMI patients with multivessel disease?

20 May 2025 – From EuroPCR 2025

Managing STEMI patients with multivessel disease is a complex challenge evolving rapidly thanks to new clinical evidence. Angela Mcinerney, Natalia Pinilla, and Matthias Götberg explore how findings from the COMPLETE trial and its intracoronary imaging substudy are reshaping treatment strategies.

Their discussion highlights the role of intracoronary...

How to manage treatment dilemmas in STEMI patients with multivessel disease?

How to efficiently and safely manage calcified left main disease?

21 May 2025 – From EuroPCR 2025

Nicola Ryan and Flavio Ribichini explore the complexities of calcified left main stem disease, emphasizing the critical role of intracoronary imaging in improving patient outcomes. They discuss the practical use of mechanical circulatory support and debate stenting strategies, offering expert insights on when single or dual...

How to efficiently and safely manage calcified left main disease?

Feasibility of sheathless Impella for protected percutaneous coronary intervention: a single-center experience

02 May 2025

Impella CP microaxial flow pump supports complete revascularisation during high-risk PCI, but standard implantation often leads to vascular complications. This article explores an initial experience with a sheathless implantation technique, which shows promise as a feasible and safe alternative.

Sheathless Impella PCI

How should I treat a left main disease with multivessel diffuse CAD? Stenting only the necessary...

28 Feb 2025

A 71-year-old male patient with a clinicial history of hypertension, dyslipidemia and active smoking was admitted for NSTEMI.

Coronary angiography showed a left main (LM) stenosis involving the bifurcation and proximal parts of the left anterior descending (LAD) and left circumflex (LCx) arteries. Right coronary artery (RCA) showed a severe...

Eva Rumiz

Author

Eva Rumiz
How should I treat a left main disease with multivessel diffuse CAD? Stenting only the necessary

Left main PCI strategies for bifurcations and trifurcations

19 Dec 2024 – From GulfPCR-GIM 2024

Explore this comprehensive session on left main PCI strategies for bifurcations and trifurcations. Discover techniques such as the triple kissing balloon inflation technique in a complex distal LM trifurcation lesion, imaging-guided multivessel PCI to left anterior descending CTO and left main bifurcation, and IVUS-guided PCI to...

Left main PCI strategies for bifurcations and trifurcations

Caught between a calcified rock and a hard place

19 Dec 2024 – From GulfPCR-GIM 2024

This session delves into the challenges of managing heavily calcified coronary lesions, particularly in complex scenarios like left main bifurcation angioplasty and in elderly patients with unstable angina. Explore innovative techniques to tackle abrupt vessel closure, situations where rotablation may fall short, and state-of-the-art approaches for...

Caught between a calcified rock and a hard place

Complications and challenging cases #2

19 Dec 2024 – From GulfPCR-GIM 2024

Dive into this session to explore a collection of challenging cases and complications encountered in interventional cardiology. From a ruptured balloon inside a coronary artery to a percutaneous ventricular septal rupture closure post myocardial infarction, uncover the strategies and techniques used to manage these complex situations....

Complications and challenging cases #2

The invasive assessment and management of the invisible component of the coronary circulation

19 Dec 2024 – From GulfPCR-GIM 2024

Explore the invisible component of the coronary circulation in this insightful session. Gain a deep understanding of the principles of microvascular invasive assessment, learn how to interpret the data, and discover tailored management strategies for microvascular dysfunction. Through case presentations on vasospastic angina and microvascular dysfunction,...

The invasive assessment and management of the invisible component of the coronary circulation

When complications storm through the cathlab #2

19 Dec 2024 – From GulfPCR-GIM 2024

Brace yourself as we delve into a captivating session showcasing a series of complex and challenging complications that can arise in the catheterization laboratory. From a coiling gone awry to a stuck burr in an elderly patient, this session offers invaluable insights and strategies for navigating...

When complications storm through the cathlab #2