Left main and multivessel disease

Latest left main and multivessel disease content in interventional cardiology - research, practice, and education

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

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Complications during left main PCI: how to manage and how to avoid

20 May 2026 – From EuroPCR 2026

This session addresses the identification, prevention, and management of complications arising during left main percutaneous coronary intervention (PCI). Through detailed case presentations and analyses, it highlights anatomical and procedural risk factors, strategies to anticipate and recognize complications such as stent deformation and coronary perforation, and effective...

Complex left main patients and PCI

20 May 2026 – From EuroPCR 2026

This session addressed the complexities of left main PCI, focusing on managing hemodynamic uncertainty in high-risk interventions, advanced techniques such as ultra-low contrast rota-tripsy PCI, precise stent positioning, and pragmatic approaches to CHIP cases, emphasizing contrast-sparing strategies and best practice balancing.

Prognostics elements on multivessel disease and coronary artery disease

20 May 2026 – From EuroPCR 2026

This session examines key prognostic elements in multivessel and coronary artery disease, featuring studies on mechanical circulatory support across LDL-C levels, biomarkers impacting periprocedural myocardial infarction, autologous cell therapy outcomes for refractory angina, and novel risk stratification indices. It also addresses prognosis in cancer patients and...

Management of a patient with complex multivessel disease involving bifurcations

19 May 2026 – From EuroPCR 2026

Complex multivessel coronary disease involving bifurcations requires careful procedural planning, imaging guidance and tailored stent strategies.

This EuroPCR 2026 session combines live educational case with insights from the NAGOMI COMPLEX study to explore contemporary approaches to complex PCI. A key focus is placed on the role of...

Management of a patient with complex multivessel disease involving bifurcations

Rescue PCI for acute or unusual left main lesions

19 May 2026 – From EuroPCR 2026

This session explores rescue PCI techniques for acute and unusual left main coronary lesions, highlighting complex cases such as left main compression syndrome in pulmonary hypertension, and challenging strategies in acute coronary syndromes with left main occlusion and anatomical variations.

Effective strategies for preventing and resolving complications of PCI in STEMI or left main patients: a case-based educational session

19 May 2026 – From EuroPCR 2026

This case-based educational session focuses on the prevention and resolution of PCI complications in STEMI and left main patients. It offers a cross-geographic perspective on prompt recognition, risk evaluation, and diverse management techniques to improve patient outcomes in high-risk PCI scenarios.

From data to decisions: calm and structured approaches to high pressure PCI

19 May 2026 – From EuroPCR 2026

Addressing high-pressure scenarios in the cath lab, this session explores calm and structured decision-making approaches for unusual and challenging PCI cases. It emphasizes optimizing management of life-threatening complications through real-time strategies and illustrative case discussions.

PCI for complex left main disease

19 May 2026 – From EuroPCR 2026

This session delves into the complexities of percutaneous coronary intervention (PCI) for left main disease, emphasizing strategic approaches to dual critical lesions and innovative techniques such as excimer laser and drug-eluting balloons. It also explores hybrid strategies for treating in-stent restenosis and redo revascularisation, offering a...

PCI of left main stenosis: LIVE Educational Case from Sant'Andrea University Hospital - Rome, Italy

19 May 2026 – From EuroPCR 2026

This live educational case from Sant'Andrea University Hospital in Rome provides a comprehensive assessment and management approach to complex left main stenosis. The session covers patient presentation, advanced imaging analysis, operator strategy, and the application of calcium modification tools, culminating in procedural debriefing and key clinical...

Beyond the angiogram: contemporary management of STEMI

19 May 2026 – From EuroPCR 2026

This session provides an in-depth review of complex STEMI cases from diverse clinical settings, emphasizing optimisation of primary PCI strategies, complication management, and individualised antithrombotic therapy. Real-world cases from Albania, Macedonia, and Slovakia illustrate diagnostic challenges and therapeutic decision-making to improve patient outcomes.