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Left main and multivessel disease

Latest left main and multivessel disease content in interventional cardiology - research, practice, and education

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

371 results

Left main complications - Part 1

21 May 2026 – From EuroPCR 2026

Focus on managing complications related to left main coronary interventions, with detailed case analyses addressing procedural pitfalls, iatrogenic dissections, and unexpected imaging challenges.

Left main PCI treatment: how Ultreon 3.0 can improve decision making and achieve optimised outcomes

20 May 2026 – From EuroPCR 2026

This session explores how to optimise left main PCI through the integration of intracoronary imaging and physiology using Ultreon 3.0 software. It highlights how this innovative technology supports decision-making, procedural planning, and stent optimisation to improve outcomes in complex lesion management.

Left main PCI treatment: how Ultreon 3.0 can improve decision making and achieve optimised outcomes

PRISM-PCI - From clarity to cure

20 May 2026 – From EuroPCR 2026

PRISM-PCI offers cutting-edge imaging innovations and treatment strategies aimed at optimizing complex PCI procedures. This session explores the 'leave nothing behind' concept with thin-strut bioresorbable scaffolds and sirolimus drug-coated balloons, updates on ultra thin-strut DES platforms, including the SORT OUT XII trial, and introduces a comprehensive...

PRISM-PCI - From clarity to cure

Tough scenarios in multivessel disease

20 May 2026 – From EuroPCR 2026

This session addresses challenging scenarios in multivessel coronary artery disease (CAD), particularly when surgical options are limited. Case discussions include IVUS-guided PCI with rotational atherectomy, management of combined severe aortic stenosis and multivessel disease, acute mitral regurgitation with cardiogenic shock, anomalous coronary anatomy, severe kidney disease,...

Navigating complexity: contemporary approaches to multivessel disease

20 May 2026 – From EuroPCR 2026

This session addresses contemporary approaches to multivessel coronary artery disease, featuring functional assessments, microvascular resistance importance in chest pain despite normal angiography, management of guide catheter-induced intramural hematoma, drug-coated balloon strategies including dual CTO, and minimal contrast PCI techniques in patients with chronic renal failure.

Bifurcation PCI with complications - Part 1

20 May 2026 – From EuroPCR 2026

This session addresses complications encountered during bifurcation PCI through real-world cases involving stent dislodgement, entrapped guidewires, failed wiring techniques, and fractured devices. It highlights technical rescue maneuvers, the role of intravascular imaging, and long-term challenges encountered in managing complex bifurcation lesions to improve procedural success and...

Complex distal LM PCI challenges (trifurcations and more)

20 May 2026 – From EuroPCR 2026

Focusing on the intricacies of complex distal left main PCI, this session covers challenging trifurcation lesions and emergency interventions. It includes IVUS-guided approaches for trifurcation PCI, management of calcified left main trifurcations, and multidisciplinary team rescue strategies for unstable left main bifurcation disease.

Choosing the right strategy for isolated ostial left anterior descending artery or circumflex coronary lesions

20 May 2026 – From EuroPCR 2026

This session examines optimal strategies for managing isolated ostial lesions in the left anterior descending and circumflex arteries, comparing left main crossover, ostial stenting, and drug-coated balloon (DCB) approaches. It emphasizes integrating multimodality imaging for informed decision-making, illustrated through detailed case discussions.

Strategical approaches to treat patients with multivessel disease

20 May 2026 – From EuroPCR 2026

This comprehensive session focuses on strategic approaches to manage patients with multivessel coronary artery disease. It covers a spectrum of topics including ostial stent implantation techniques, the impact of center volume on CT-guided angiography post-CABG, and physiology-guided PCI versus angiography alone. Insights into percutaneous revascularisation strategies...

Major Late-Breaking Trials from EuroPCR 2026

20 May 2026 – From EuroPCR 2026

This session presents major late-breaking trials from EuroPCR 2026, reviewing contemporary evidence on coronary revascularization in TAVI patients, long-term outcomes of PCI versus CABG for left main disease, and comparative effectiveness of LAA closure versus NOAC in atrial fibrillation across age groups, with clinical practice implications.