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Challenging TAVI

16 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities encountered in transcatheter aortic valve implantation (TAVI) in challenging anatomical settings. It reviews management of bicuspid valves with calcification, horizontal aorta, coronary artery anomalies, and navigation of difficult angles. Case studies illustrate techniques to optimize commissural alignment and strategies to address...

Paravalvular leak closure - Part 1

17 Nov 2025 – From PCR London Valves 2025

This session focuses on paravalvular leak closure challenges and solutions. It features complex cases such as extraction of plugs jailed between mechanical valves, managing leaks associated with severe annular calcification, aorto-mitral curtain leaks, device embolisation post-TMVR, and device-related haemolysis after closure procedures.

TAVI: unusual complications

16 Nov 2025 – From PCR London Valves 2025

This session examines rare and unusual complications arising from TAVI procedures. Topics include early recognition and management of frozen leaflets, ventricular septal perforation post-valve-in-valve TAVI, acute leaflet dysfunction, aorto-ventricular fistula formation, and percutaneous closure techniques for fistulas involving the right coronary sinus and right ventricle, emphasizing...

TAVI valve-in-valve - Part 4

17 Nov 2025 – From PCR London Valves 2025

This advanced session addresses complex valve-in-valve TAVI procedures, including management of challenging cases involving combined valve-in-valve TAVI and thoracic endovascular aortic repair. It also discusses technical considerations such as retrieval of lost stents in the left main coronary artery and critical aspects of TAV-in-TAV selection, sizing,...

Nightmare mitral interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex mitral valve intervention cases highlighting procedural challenges and innovative solutions. It includes management of embolised transcatheter mitral valve replacements (TMVR), bailout redo transcatheter edge-to-edge repair (TEER), complications such as acute hypoxia and atrial wall perforations, and the application of TAVI skills in...

Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

Featured research - TAVI: Redo strategies, valve performance & access safety

17 Nov 2025 – From PCR London Valves 2025

This detailed session investigates critical aspects of TAVI procedures including the safety of selective and routine femoral access angiography post-TAVI, outcomes from the ReTAVI registry focusing on redo-TAVI in various valve frames, and a comparative analysis of JenaValve versus Evolut transcatheter heart valves in severe aortic...

Featured research - TAVI: Redo strategies, valve performance & access safety

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

Dapagliflozin in acute myocardial infarction: Cardiometabolic benefits without impact on cardiovascular death or heart failure hospitalization: The jury is still out

14 Nov 2023

Luis Ortega Paz provides his take on DAPA-MI - A registry-based randomized trial of dapagliflozin in patient with acute myocardial infarction without diabetes, which was presented by Stefan James at AHA 2023 in Philadelphia.

Luis Ortega-Paz

Author

Luis Ortega-Paz
DAPA-MI - A registry-based randomized trial of dapagliflozin in patient with acute myocardial infarction without diabetes

PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients With Acute Myocardial Infarction

03 Apr 2022

Nicola Ryan provides a PICOT analysis of PACMAN AMI: a double-blind, placebo-controlled, randomized trial presented at ACC 2022 and simultaneously published in JAMA.

Nicola Ryan

Author

Nicola Ryan
PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients With Acute Myocardial Infarction: A Double-blind, Placebo-controlled, Randomized Trial

NOTION-3 - Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation

01 Sep 2024

Make the most of the insights from Jacob Thomsen Loenborg’s interview with Chiara De Biase and Ali Nazmi Calik’s article to capture the key takeaways from this trial, simultaneously published in the NEJM, presented at the ESC Congress 2024 in London.

Author

Chiara De Biase
Jacob Lønborg

Author

Jacob Lønborg

Author

Ali Nazmi Calik
NOTION 3
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