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3140 results

Featured research - Left atrial appendage occlusion and paravalvular leak closure

16 Nov 2025 – From PCR London Valves 2025

This featured research session delves into innovative transcatheter interventions including left atrial appendage occlusion and paravalvular leak closure. It covers clinical and hemodynamic outcomes of atrial shunting in heart failure, endothelialisation issues post-paravalvular leak closure, and long-term patient follow-up. Advanced guidance modalities and simulation technologies for...

From diagnosis to device: decision-making and planning for mitral valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session offers a comprehensive overview of decision-making and procedural planning for transcatheter mitral valve interventions. It emphasizes patient-specific factors, advanced imaging for valve morphology assessment, device selection, and the integration of emerging technologies to tailor optimal treatment strategies for mitral valve disease.

From diagnosis to device: decision-making and planning for mitral valve interventions

Rapid fire on ortothopic TTVR

16 Nov 2025 – From PCR London Valves 2025

This rapid-fire session presents an overview of the latest orthotopic transcatheter tricuspid valve replacement (TTVR) devices. It features concise discussions on multiple innovative systems including Evoque, Laplace, VDyne, Topaz, and Cardiovalve, offering insights into their design characteristics and clinical applications in tricuspid valve disease management.

Featured research - Tricuspid valve interventions - Part 2

16 Nov 2025 – From PCR London Valves 2025

This session highlights recent advances in tricuspid valve interventions with a focus on complex clinical scenarios. Topics include percutaneous annuloplasty as a bridge to edge-to-edge repair, long-term outcomes from the TriCLASP study, novel stratification methods to guide intervention, liver stiffness prognostics, right atrial remodeling post-repair, and...

Early Career Research Award Final

17 Nov 2025 – From PCR London Valves 2025

Highlighting pioneering research in structural heart interventions, this session presents studies on the impact of transcatheter tricuspid valve replacement (TTVR) on left ventricular geometry and function, myocardial remodeling in aortic stenosis, physiological responses after mitral and tricuspid edge-to-edge repairs, advancing the understanding of device effects on...

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

Challenging TAVI

16 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities encountered in transcatheter aortic valve implantation (TAVI) in challenging anatomical settings. It reviews management of bicuspid valves with calcification, horizontal aorta, coronary artery anomalies, and navigation of difficult angles. Case studies illustrate techniques to optimize commissural alignment and strategies to address...

Featured research - Mitral valve interventions: Physiology & device innovation

17 Nov 2025 – From PCR London Valves 2025

This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...

Featured research - Mitral valve interventions: Physiology & device innovation

TAVI: unusual complications

16 Nov 2025 – From PCR London Valves 2025

This session examines rare and unusual complications arising from TAVI procedures. Topics include early recognition and management of frozen leaflets, ventricular septal perforation post-valve-in-valve TAVI, acute leaflet dysfunction, aorto-ventricular fistula formation, and percutaneous closure techniques for fistulas involving the right coronary sinus and right ventricle, emphasizing...

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Nightmare mitral interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex mitral valve intervention cases highlighting procedural challenges and innovative solutions. It includes management of embolised transcatheter mitral valve replacements (TMVR), bailout redo transcatheter edge-to-edge repair (TEER), complications such as acute hypoxia and atrial wall perforations, and the application of TAVI skills in...

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

TAVI in shock

17 Nov 2025 – From PCR London Valves 2025

This session presents advanced cases of TAVI performed in patients experiencing cardiogenic shock. It includes valve-in-valve TAVI under ECMO support, innovative antegrade-retrograde crossing techniques for legacy surgical bioprostheses, and management of acute aortic regurgitation following prosthesis failure or TAVI.

Featured research - Tricuspid valve intervention: latest advanced insights

17 Nov 2025 – From PCR London Valves 2025

This featured research session delves into advanced insights on tricuspid valve interventions, focusing on the significance of right ventricular function and dimension in patient outcomes. It explores prognostic factors such as right ventricular loading mismatch, innovations like the clover technique in Pascal TEER, myocardial work recovery,...

Featured research - Tricuspid valve intervention: latest advanced insights

How to perform angiographic check after large-sheath removal in single access procedures

18 Mar 2024

In the absence of other arterial access, this step-by-step tutorial shows how to perform anterograde angiography of the arterial axis after removal of the large sheath, making it easier to recognise and rapidly manage vascular complications such as arterial lesions and haemostasis failure.

Francesco Burzotta

Author

Francesco Burzotta
Lazzaro Paraggio

Author

Lazzaro Paraggio
Mattia Lunardi

Author

Mattia Lunardi
Cristina Aurigemma

Author

Cristina Aurigemma
Enrico Romagnoli

Author

Enrico Romagnoli

Author

Francesco Fracassi

Author

Antonino Buffon
C. Trani

Author

Carlo Trani
How to perform angiographic check after large-sheath removal in single access procedures

OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

08 Nov 2022

Ali Nazmi Calik provides his take on OPTION, which was presented during AHA 2022 in Chicago.

Author

Ali Nazmi Calik
OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

The top ten impactful papers from 2025 on tricuspid intervention we almost missed

13 Jan 2026

Transcatheter interventions have rapidly reshaped the management of tricuspid valve disease, with landmark trials establishing feasibility and early clinical benefit.

Beyond these pivotal studies, a series of less visible but highly informative papers addressed mechanisms, complications, patient phenotypes, and unintended consequences of intervention.

This curated selection highlights ten impactful tricuspid...

Alessandro Sticchi

Author

Alessandro Sticchi
The top ten impactful papers on tricuspid intervention we almost missed

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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