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First-in-human studies in cardiovascular devices: from first 10 patients to global innovation — How efficient early studies advance emerging technologies

20 May 2026 – From EuroPCR 2026

Understand the pivotal role of first-in-human studies in advancing cardiovascular device innovation through operational insights from early patient experiences. This session reviews cutting-edge technologies including percutaneous left ventricular assist devices, transcatheter leaflet augmentation, physiology-guided PCI, synchronized diaphragmatic stimulation, pulmonary artery denervation, and perspectives on translating early...

Innovation in transcatheter mitral valve interventions

21 May 2026 – From EuroPCR 2026

This comprehensive session presents the latest innovations in transcatheter mitral valve interventions, highlighting cutting-edge devices and clinical experiences. Topics include early feasibility studies of novel hemivalve systems, first-in-human experiences with new mitral valve replacement technologies, advances in transcatheter edge-to-edge repair (TEER) with one-year outcome data, and...

Routine primary PCI: what can go wrong?

21 May 2026 – From EuroPCR 2026

This session offers an in-depth examination of potential complications during routine primary PCI, focusing on prevention and management strategies. Key learning points include understanding no-reflow phenomena, managing STEMI in post-CABG patients, and handling thrombus burden effectively. Real-world cases illustrate decision-making processes and therapeutic approaches to optimize...

Routine primary PCI: what can go wrong?

Mitral paravalvular leak closure: case-bases strategies

20 May 2026 – From EuroPCR 2026

This session presents case-based strategies for mitral paravalvular leak closure, highlighting complex percutaneous approaches including multivalvular failure management, apical access techniques, and transatrial direct surgical valve-in-MAC procedures. It features challenging clinical scenarios demonstrating innovative solutions for hemolytic leaks and complex paravalvular defects.

Insight from recent evidence in coronary artery disease: value of DCB for de novo lesions (SELUTION) and imaging for left main PCI (OPTIMAL)

21 May 2026 – From EuroPCR 2026

This session reviews pivotal recent evidence impacting daily practice in coronary artery disease management. It discusses the role of drug-coated balloons (DCB) for de novo lesions as evaluated in the SELUTION trial and evaluates intracoronary imaging strategies for left main PCI as presented in the OPTIMAL...

Insight from recent evidence in coronary artery disease: value of DCB for de novo lesions (SELUTION) and imaging for left main PCI (OPTIMAL)

The structural bailout playbook: managing complications

21 May 2026 – From EuroPCR 2026

The session presents a practical structural bailout playbook focused on managing complex complications during structural heart interventions. It features challenging cases such as unusual atrial septal defect closure complications, navigation of a displaced patent ductus arteriosus stent in infants, percutaneous closure of mitral paravalvular leaks with...

The structural bailout playbook: managing complications

Revascularisation in patients with multivessel disease and severe left ventricular impairment

21 May 2026 – From EuroPCR 2026

This session focuses on revascularisation strategies for patients with multivessel coronary disease complicated by severe left ventricular impairment. It emphasizes patient selection criteria, the crucial role of the heart team in decision-making, and optimization of percutaneous revascularisation outcomes. The content includes comprehensive case presentations and discussions...

Revascularisation in patients with multivessel disease and severe left ventricular impairment

Advanced heart failure: left ventricular assist device as bridge to optimise guided-directed medical therapy

21 May 2026 – From EuroPCR 2026

This session explores advanced heart failure management with a focus on guided-directed medical therapy and the role of left ventricular assist devices (LVAD) as a bridge to therapy optimization. It discusses clinical, imaging, and biological parameters indicating LVAD use and highlights devices such as the Impella...

Advanced heart failure: left ventricular assist device as bridge to optimise guided-directed medical therapy

How to perform angiographic check after large-sheath removal in single access procedures

18 Mar 2024

In the absence of other arterial access, this step-by-step tutorial shows how to perform anterograde angiography of the arterial axis after removal of the large sheath, making it easier to recognise and rapidly manage vascular complications such as arterial lesions and haemostasis failure.

Francesco Burzotta

Author

Francesco Burzotta
Lazzaro Paraggio

Author

Lazzaro Paraggio
Mattia Lunardi

Author

Mattia Lunardi
Cristina Aurigemma

Author

Cristina Aurigemma
Enrico Romagnoli

Author

Enrico Romagnoli

Author

Francesco Fracassi

Author

Antonino Buffon
C. Trani

Author

Carlo Trani
How to perform angiographic check after large-sheath removal in single access procedures

Self-made steerable catheter to cross the aortic valve in severe aortic stenosis

15 Apr 2026

When standard catheters and wires repeatedly fail to cross a severely stenotic aortic valve, a simple modification of readily available equipment may provide a solution.

This step-by-step tutorial explains how to create and use a self-made steerable catheter system to facilitate valve crossing in complex TAVI anatomies.

Author

Osama Bisht
Won-Keun Kim

Author

Won-Keun Kim
Robert R. Flieger

Author

Robert R. Flieger
Self-made steerable catheter to cross the aortic valve in severe aortic stenosis

OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

08 Nov 2022

Ali Nazmi Calik provides his take on OPTION, which was presented during AHA 2022 in Chicago.

Author

Ali Nazmi Calik
OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

The top ten impactful papers from 2025 on tricuspid intervention we almost missed

13 Jan 2026

Transcatheter interventions have rapidly reshaped the management of tricuspid valve disease, with landmark trials establishing feasibility and early clinical benefit.

Beyond these pivotal studies, a series of less visible but highly informative papers addressed mechanisms, complications, patient phenotypes, and unintended consequences of intervention.

This curated selection highlights ten impactful tricuspid...

Alessandro Sticchi

Author

Alessandro Sticchi
The top ten impactful papers on tricuspid intervention we almost missed

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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