Calcified lesions

Find all the latest content on calcified lesions published on this website.

This section revolves around the complexity of calcified coronary lesions and their treatment, from specialised balloon technology to atherectomy devices and lithotripsy. Learn all about the value of invasive imaging and coronary physiology, with many clinical cases showing various treatment modalities and strategies.

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Cracking calcium in modern PCI

10 Dec 2025 – From GulfPCR-GIM 2025

Calcified coronary lesions are a major challenge in PCI. This PCRGulf-GIM 2025 session showcases a complex case with intravascular imaging, highlighting how IVUS 123 guides each step.

From planning the procedure and understanding calcium distribution, to lesion preparation with modern modification tools, and post-PCI assessment to confirm...

Cracking calcium in modern PCI

Seeing is believing: OCT-guided calcium modification in complex PCI

10 Dec 2025 – From GulfPCR-GIM 2025

Explore the management of heavily calcified LAD lesions in this PCRGulf-GIM 2025 session. Discover how OCT imaging guides lesion assessment, differentiates superficial from deep calcium, and informs the need for plaque modification. Learn when and how to use orbital atherectomy or intravascular lithotripsy, and follow the...

Seeing is believing: OCT-guided calcium modification in complex PCI

Abstracts session 1

10 Dec 2025 – From GulfPCR-GIM 2025

This abstracts session presents contemporary research and clinical insights in interventional cardiology, covering topics such as colchicine therapy post-stenting, ranolazine use in chronic coronary syndrome, artificial intelligence applications in quantitative coronary analysis, and optimization techniques in transcatheter aortic valve implantation. It also explores novel predictors of...

Abstracts session 1

Complex bifurcation interventions

10 Dec 2025 – From GulfPCR-GIM 2025

This session examines complex bifurcation interventions, addressing challenging cases such as isolated Medina 0,0,1 left main bifurcation and imaging-guided trifurcation angioplasty in acute coronary syndromes. It emphasizes strategic approaches and device selection to overcome anatomical complexities, manage complications, and achieve successful outcomes in bifurcation PCI.

Complex bifurcation interventions

Calcified lesions: caught between a rock and a hard place

10 Dec 2025 – From GulfPCR-GIM 2025

This session focuses on the challenges of treating calcified coronary lesions, emphasizing the use of intravascular ultrasound (IVUS)-guided rotablation and the limitations of rotatripsy in complex bifurcation angioplasty. It covers innovative strategies including off-label Shockwave lithotripsy in stented lesions, management of calcified nodules, and approaches to...

Calcified lesions: caught between a rock and a hard place

Challenging cases from the East

10 Dec 2025 – From GulfPCR-GIM 2025

This session from Eastern cardiology centers addresses complex interventional challenges including recurrent left internal mammary artery (LIMA) failure, management of transcatheter aortic valve implantation (TAVI) complications, and treatment of heavily calcified coronary lesions. Through detailed case presentations and key learnings, it offers valuable insights into successful...

Challenging cases from the East

A randomised, multicenter, non-inferiority comparison of intravascular lithotripsy and super-high-pressure non-compliant balloons for treatment of calcified and refractory coronary lesions - The VICTORY trial

27 Oct 2025

Mirvat Alasnag provides her take on the VICTORY trial presented by Matthias Bossard at TCT 2025 in San Francisco.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
VICTORY: Intravascular lithotripsy vs. super-high-pressure PTCA in calcified and refractory coronary lesions

Calcified coronary lesions

21 Oct 2025

This freshly updated chapter extensively describes percutaneous tools and techniques to assess and treat challenging calcified lesions.

Authors :

Farrel Hellig, Pieter Van Wyk, Emanuele Barbato, Shaheen Pandie
Calcified coronary lesions

Provisional stenting with a scaffold stent and DCB in calcified left main bifucation - LIVE Case

11 Oct 2025 – From AICT-AsiaPCR 2025

A 59-year-old male presented with CCS for three months, with diabetes and normal LV function (72%). Coronary angiography showed a calcified left main stenosis (Medina 1,1,1) and diffuse calcification of the proximal and mid LAD. The LCX QFR was 0.86.

Treatment included extensive lesion preparation with lithotripsy...

Provisional stenting with a scaffold stent and DCB in calcified left main bifucation - LIVE Case

Retrievals, foreign bodies and entrapments

11 Oct 2025 – From AICT-AsiaPCR 2025

This session addresses the complexities of retrievals, foreign bodies, and entrapments in interventional cardiology. It presents clinical cases illustrating percutaneous retrieval techniques, management of catheter fractures, iatrogenic dissections, and innovative solutions for challenging scenarios. Emphasis is placed on precision, prevention strategies, and effective problem-solving to mitigate...

Coronary complications and rescue cases

11 Oct 2025 – From AICT-AsiaPCR 2025

This compelling session addresses complex coronary complications and rescue cases encountered in the cath lab. Through a series of challenging case studies, it highlights critical scenarios such as silent coronary artery threats, procedural nightmares, coronary perforations, and innovative rescue strategies that transform high-risk situations into successful...

Coronary complications and rescue cases

PCR @ TCT 2025 - Get the international perspective!

15 Oct 2025

Thanks to the contribution of a team of interventional cardiologists from around the globe, get the international perspective on Late-breaking Clinical Trials and Science released at TCT 2025 - check out the list below.

PCRonline @ TCT 2025 - get the international perspective!

Calcium nodule in circumflex ostium: a complex problem

31 Oct 2025

Analyse this case of an 83-year-old male patient, hypertensive, ex-smoker, with severe COPD and peripheral arterial disease with unstable angina. Coronary angiography revealed a severely calcified lesion in a complex anatomical area, making revascularisation a therapeutic challenge.

Jorge Perea

Author

Jorge Perea
Javier Suarez de Lezo

Author

Javier Suarez de Lezo
Soledad Ojeda

Author

Soledad Ojeda
Prof. Manuel Pan

Author

Manuel Pan
Calcium nodule in circumflex ostium: a complex problem

Optical coherence tomography- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial

28 Aug 2025

In the overall population (n = 2,114), there was a significant interaction between the effect of randomisation to OCT guidance vs angiography guidance in lesions with moderate/severe calcification (n = 1,082) vs no/mild calcification (n = 1,032) on the 2-year rate of TVF (Pinteraction = 0.01).

Reviewer

Salvatore Brugaletta
OCT- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial

Hostile left main calcific stenosis in HFrEF

20 Aug 2025

Analyse this case to find out how to successfully manage a patient with a severely calcific left main stenosis and severely reduced ejection fraction.

Emanuele Gallinoro

Author

Emanuele Gallinoro
Riccardo Terzi

Author

Riccardo Terzi

Author

Francesca Di Lenarda
Hostile left main calcific stenosis in HFrEF

Remove the shaft technique: tips and tricks

30 Jul 2025

When a rota burr stalls in a calcified artery, quick thinking and the right technique are critical. Discover a proven method to recover the burr safely and avoid surgery.

Petros Dardas

Author

Petros Dardas
Nikolaos Mezilis

Author

Nikolaos Mezilis
Remove the shaft technique: tips and tricks

How to manage a stalled burr: tips and tricks

30 Jul 2025

A stalled rota burr is every operator’s nightmare — but being prepared can make all the difference. In this case, an 80-year-old patient with severe calcification in the proximal and mid LAD faces exactly that complication.

What’s your first step to safely retrieve the burr and complete...

Petros Dardas

Author

Petros Dardas
Nikolaos Mezilis

Author

Nikolaos Mezilis
How to manage a stalled burr: Tips and tricks

How to avoid using a new balloon for trapping?

10 Jul 2025

Trapping wires during complex PCI is essential but dedicated trapping balloons aren’t always on hand — and costs add up fast. This My Toolkit tip shows you how to safely reuse a standard PTCA balloon by stiffening its shaft with the original stylet, making valve crossing...

Helena Correia

Author

Helena Correia
João Silva Marques

Author

João Silva Marques
How to avoid using a new balloon for trapping?

When high calcium burden meets a 75 year-old patient with previous CABG + SAVR + MVr

02 Jul 2025

This case illustrates how a fragile patient with severe three-vessel disease involving LM/LAD was treated. Watch now to find out more, and share your thoughts!

Filippo Pensotti

Author

Filippo Pensotti
Luca Testa

Author

Luca Testa
When high calcium burden meets a 75 year-old patient with previous CABG + SAVR + MVr: an intricate PCI stands as the last line of defense

Best companion's case on intravascular lithotripsy

23 May 2025 – From EuroPCR 2025

Join this session focusing on intravascular lithotripsy in challenging cases, emphasizing device and drug synergy, IVUS guidance, and strategies to avoid exacerbating complications. Clinical cases demonstrate management of tough calcified lesions with novel approaches.

Best companion's case on intravascular lithotripsy