Calcified lesions

Find all the latest content on calcified lesions published on this website.

This section revolves around the complexity of calcified coronary lesions and their treatment, from specialised balloon technology to atherectomy devices and lithotripsy. Learn all about the value of invasive imaging and coronary physiology, with many clinical cases showing various treatment modalities and strategies.

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Intravascular lithotripsy in comparison to rotational atherectomy for calcified lesions: the ICARE OFDI randomised trial

01 Jun 2026

In patients with moderate-to-severe calcified coronary lesions, ICARE OFDI evaluates IVL versus rotational atherectomy as lesion preparation strategies, with OFDI-based assessment of stent results.

Emanuele Gallinoro

Reviewer

Emanuele Gallinoro
ICARE OFDI: IVL vs rotational atherectomy for calcified lesions

Shockwave C2 Aero: Early experience in complex calcified coronary lesions

27 May 2026

Dr. Yousif Ahmad and Dr. Brett Wanamaker discuss how improved deliverability may influence calcium modification strategies in complex PCI.

In this case-based discussion, Dr. Yousif Ahmad and Dr. Brett Wanamaker share their early experience with Shockwave C2 Aero in complex calcified coronary anatomy. Through challenging real-world cases,...

Shockwave C2 Aero: Early experience in complex calcified coronary lesions

Euro4C strides forward with a new president

21 May 2026

Euro4C – the Contemporary Care of patients with Calcified Complex lesions initiative – aims to improve clinical outcomes for patients with advanced, diffuse and calcified atherosclerotic CAD.

Euro4C strides forward with a new president

Breaking the calcium challenge: the power of Hertz with LithiX intravascular lithotripsy

20 May 2026 – From EuroPCR 2026

Calcified coronary lesions remain a major challenge in PCI, particularly when lesion rigidity limits device delivery and optimal stent expansion.

This EuroPCR 2026 session focuses on contemporary calcium modification strategies and the role of the Hertz contact intravascular lithotripsy (HC-IVL) system in simplifying treatment of complex calcified...

Breaking the calcium challenge: the power of Hertz with LithiX intravascular lithotripsy

High definition IVUS-guided treatment strategies in calcified stenoses

20 May 2026 – From EuroPCR 2026

Severely calcified coronary stenoses remain one of the most challenging subsets in contemporary PCI, requiring precise lesion assessment and tailored treatment strategies.

This EuroPCR 2026 session focuses on how high-definition intravascular ultrasound (IVUS) is changing the way these lesions are approached in daily practice.

HD-IVUS enables detailed detection...

High definition IVUS-guided treatment strategies in calcified stenoses

What is the future of intracoronary imaging for assessment of calcified lesions?

21 May 2026 – From EuroPCR 2026

In this conversation, Angela McInerney and Ziad Ali explore the evolving role of imaging in calcified coronary artery disease, the growing evidence supporting intracoronary imaging, particularly OCT and IVUS, and how detailed plaque characterisation and scoring systems can improve procedural planning and outcomes. Looking ahead, they...

What is the future of imaging for assessment of calcified lesions?

Calcium Skills Lab: EuroPCR 2026 highlights

19 May 2026 – From EuroPCR 2026

As the management of heavily calcified coronary lesions becomes increasingly complex, the need for practical, hands-on education continues to grow. At EuroPCR 2026, a brand-new initiative aims to address this challenge: the Calcium Skills Lab.

In this discussion, Angela McInerney and Mohamed Abdel-Wahab present this innovative programme...

Calcium Skills Lab: EuroPCR 2026 highlights

Coronary calcification versus thrombus: a deceptive ambiguity revealed in the aftermath of embolisation

07 Apr 2026

Discriminating between coronary calcification and thrombus in acute settings remains a diagnostic challenge with significant implications for interventional decision-making.

Imran Hanif Hashmi

Author

Imran Hanif Hashmi
Minahil Tariq Sheikh

Author

Minahil Tariq Sheikh
Ahmad Usama Wali

Author

Ahmad Usama Wali
Coronary calcification versus thrombus: a deceptive ambiguity revealed in the aftermath of embolisation

Modern approach to tackle rocky roads

02 Jun 2026

Complex PCI of a calcified vessel in a 72-year-old gentleman with NSTEACS and markedly reduced LV function.

This case highlights how to tackle a challenging access and a difficult coronary lesion in a patient with scarce hemodynamic reserve.

Author

Ivan Vosko

Author

Otar Kvavadze

Author

Gabor G Toth
 Modern approach to tackle rocky roads

Intravascular lithotripsy or mechanical debulking in complex calcified coronary arteries: multicenter, prospective ROLLING STONE study

19 Mar 2026

The ROLLING STONE registry compares intravascular lithotripsy (IVL) and atherectomy (rotational and orbital) for treating heavily calcified coronary arteries, assessing real-world safety and effectiveness in percutaneous coronary interventions (PCI).

Reviewer

Aaysha Cader
Intravascular lithotripsy or mechanical debulking in complex calcified coronary arteries: multicenter, prospective ROLLING STONE study

Contemporary approach in the treatment of calcified coronary artery disease

28 Feb 2026 – From Euro4C Annual Meeting 2026

Adopt a contemporary approach to managing calcified coronary artery disease by leveraging high-definition IVUS for lesion assessment and morphology evaluation. Learn to tailor calcium modification strategies based on IVUS findings and combine available tools to optimize treatment outcomes according to patient and lesion profiles.

Contemporary approach in the treatment of calcified coronary artery disease

Mechanical circulatory support protected PCI in complex calcified patients

28 Feb 2026 – From Euro4C Annual Meeting 2026

Explore the critical role of mechanical circulatory support with Impella in complex calcified patients undergoing PCI. This session delves into patient selection criteria, reviews the latest evidence, and discusses strategies to prevent and manage device-related complications, supported by case presentations focusing on imaging analysis, vascular access...

Mechanical circulatory support protected PCI in complex calcified patients

How to avoid and manage complications

28 Feb 2026 – From Euro4C Annual Meeting 2026

Build a comprehensive complication-management toolbox tailored for PCI in heavily calcified vessels. This session covers prevention and management techniques for complications arising from severely calcified lesions, illustrated by practical cases and expert insights into risky lesions and challenging devices.

How to avoid and manage complications

Drug-eluting balloon in calcified lesions and complex lesions

28 Feb 2026 – From Euro4C Annual Meeting 2026

This session explores the application of drug-eluting balloons (DCB) in managing calcified and complex coronary lesions. Emphasis is placed on identifying appropriate lesions for a DCB-only strategy, the critical role of vessel preparation prior to drug delivery, and the long-term physiological assessment following treatment, supported by...

Drug-eluting balloon in calcified lesions and complex lesions

It is a calcified left main: do it well, do it safely

28 Feb 2026 – From Euro4C Annual Meeting 2026

This session addresses the complexities of percutaneous coronary intervention (PCI) in calcified left main coronary artery disease. It covers comprehensive planning including mechanical circulatory support, intravascular imaging, and bifurcation strategies. Attendees will also learn to anticipate and manage potential complications and apply various tools to ensure...

It is a calcified left main: do it well, do it safely

ResilCard - A resilience assessment tool to ensure cardiovascular care continuity during crises

28 Feb 2026 – From Euro4C Annual Meeting 2026

Introducing ResilCard, a novel resilience assessment tool designed to maintain continuity of cardiovascular care during crises. This session highlights the importance of preparedness and adaptive strategies to ensure uninterrupted patient management in challenging healthcare environments.

ResilCard - A resilience assessment tool to ensure cardiovascular care continuity during crises

The best cases of the Euro4C PCRonline website

28 Feb 2026 – From Euro4C Annual Meeting 2026

This session presents some of the most instructive and challenging cases featured on the Euro4C PCRonline website. The cases encompass management of stalled rotational atherectomy burrs, combined use of intravascular lithotripsy and Impella in saphenous vein grafts, complexities of calcium in tortuous anatomy, and strategies for...

The best cases of the Euro4C PCRonline website

Closing Ceremony

28 Feb 2026 – From Euro4C Annual Meeting 2026

The closing ceremony marks the conclusion of the conference, providing a summary of key learnings, acknowledgments, and final reflections on the advancements and discussions presented throughout the event.

Euro4C Annual Meeting 2026 Closing Ceremony

Welcome to the Euro4C Annual Meeting 2026

27 Feb 2026 – From Euro4C Annual Meeting 2026

This introductory session sets the stage for a comprehensive exploration of interventional cardiology topics, providing attendees with an overview and framework for the upcoming educational content.

Welcome to the Euro4C

Algorithm approach for severe calcified lesion, what is new?

27 Feb 2026 – From Euro4C Annual Meeting 2026

This session presents the latest algorithmic approaches for managing severe calcified lesions. Attendees will learn to recognize plaque morphologies using intravascular imaging, evaluate the capabilities of current imaging technologies, and understand updated guideline recommendations for optimal treatment strategies.

Algorithm approach for severe calcified lesion, what is new?