David Hildick-Smith
Latest contributions
Ascending into the future with drug-coated balloons
21 May 2026 – From EuroPCR 2026
Step into the future of interventional cardiology with comprehensive insights into drug‑coated balloons (DCB). This session covers the new DCB ARC guidelines, previews findings from the impactful BASKET BALL randomised trial, and examines real-world evidence from the SCORE registry. It also addresses the optimisation of acute...
Long-term mortality following PCI with DES vs. CABG for left main disease
21 May 2026 – From EuroPCR 2026
This major late-breaking trial from EuroPCR 2026 presents a landmark patient-level meta-analysis comparing PCI with drug-eluting stents (DES) versus CABG for left main coronary artery disease. Combining long-term data from the EXCEL, NOBLE, PRECOMBAT, and SYNTAX trials, the analysis found remarkably similar mortality outcomes between the...
Mitral interventions: procedural risk assessment and interventions
21 May 2026 – From EuroPCR 2026
Focused on mitral valve interventions, this session covers procedural risk assessment and outcomes following transcatheter edge-to-edge repair (TEER). Topics include predictive risk scores, technical complexity, pulmonary artery pressure indices, right ventricle-pulmonary artery coupling, and novel imaging predictors influencing procedural success and patient prognosis.
Is DCB the new gold standard for side branch treatment in bifurcation?
21 May 2026 – From EuroPCR 2026
This session explores the emerging role of drug-coated balloons (DCB) as a potential new standard for side branch treatment in bifurcation lesions. It focuses on selecting appropriate indications, optimal vessel preparation and delivery timing, and executing stepwise DCB strategies versus hybrid approaches to maximize clinical outcomes.
Complex bifurcation PCI: LIVE Educational Case from Leipzig Heart Centre - Leipzig, Germany
21 May 2026 – From EuroPCR 2026
Through a live educational case from Leipzig Heart Centre, this session addresses the complexities of bifurcation PCI. It discusses criteria defining complex bifurcation lesions, management strategies for challenging side branch access, and evaluates treatment options for true bifurcation lesions. The session includes patient presentation, detailed imaging...
Major Late-Breaking Trials from EuroPCR 2026
20 May 2026 – From EuroPCR 2026
This session presents major late-breaking trials from EuroPCR 2026, reviewing contemporary evidence on coronary revascularization in TAVI patients, long-term outcomes of PCI versus CABG for left main disease, and comparative effectiveness of LAA closure versus NOAC in atrial fibrillation across age groups, with clinical practice implications.
DCB in contemporary PCI: evidence, technique and physiology-guided decision-making
19 May 2026 – From EuroPCR 2026
This EuroPCR 2026 session explores the evolving role of drug-coated balloons (DCB) in contemporary PCI, highlighting how growing clinical evidence, refined procedural strategies and physiology-guided tools are reshaping everyday practice.
The discussion reviews the latest data supporting DCB use, including long-term outcomes from major registries and trials...
TAVI and coronary artery disease: we need the COMPLETE answer!
19 May 2026 – From EuroPCR 2026
Addressing the intersection of transcatheter aortic valve implantation (TAVI) and coronary artery disease, this session reviews contemporary surgical and interventional literature to elucidate current practices. It underscores the need for a large international randomized controlled trial to provide definitive guidance for managing patients with concomitant aortic...
Complications of paravalvular leak closure
18 Nov 2025 – From PCR London Valves 2025
This session addresses the complexities and risks associated with paravalvular leak (PVL) closure. It offers detailed analysis of principal complications, prevention techniques, and practical management strategies shared by experienced operators. Case studies illustrate complications such as device embolisation, prosthetic valve disc impingement, and delivery failures, along...
The index valve matters: optimal index TAVI for a lifetime of possibilities
18 Nov 2025 – From PCR London Valves 2025
Discover how thoughtful index valve selection and implantation techniques can shape the long-term management of patients undergoing TAVI. This PCR London Valves 2025 session highlights treatment considerations for low- and intermediate-risk patients, explores how valve choice affects the feasibility of future interventions, and examines strategies to...
Myval THV series - Optimise patient outcomes with novel design, data and daily clinical practice
17 Nov 2025 – From PCR London Valves 2025
Discover the essential takeaways from the Myval THV series for improving TAVI outcomes. Learn from high-volume operators how pre-procedural planning, imaging, and sizing rationale guide optimal patient management. See step-by-step implantation of the next-gen Myval Octapro+, including the OctaAlign technique, and understand how precise deployment and...
Featured research - Mitral valve interventions: Physiology & device innovation
17 Nov 2025 – From PCR London Valves 2025
This session highlights groundbreaking research on mitral valve interventions featuring advanced transcatheter techniques. Topics include coronary physiology assessment with vFFR in severe mitral regurgitation, predictive versus actual outcomes in TMVR, innovative devices like Epygon and INNOVALVE, and novel approaches such as the ReNiva posterior leaflet replacement...
Paravalvular leaks and VSD percutaneous closure - Recorded cases
17 Nov 2025 – From PCR London Valves 2025
Recorded case 1: A 56-year-old female with a prior mechanical mitral valve replacement (Star GK, 2018), permanent AF, and normal LV function presented with recurrent HF admissions due to paravalvular leaks. She was treated with implantation of multiple plugs via a transseptal approach using a Destination...
Getting the full potential of the supra-annular valve in a changing landscape
16 Nov 2025 – From PCR London Valves 2025
This session explores the evolving landscape of transcatheter aortic valve implantation (TAVI) with a focus on supra-annular valve technology. It covers techniques for achieving commissural alignment, considerations for small aortic annuli, and advantages in treating bicuspid aortic valve disease, supported by clinical data and illustrative cases.
Managing difficult problems during TAVI procedures
22 May 2025 – From EuroPCR 2025
This session reviews difficult problems and complications encountered during TAVI procedures. Learn from real-world cases, expert treatment strategies, and key takeaways to enhance management and improve patient outcomes in challenging scenarios.
New devices for structural interventions
21 May 2025 – From EuroPCR 2025
Discover emerging devices transforming structural heart interventions. This session highlights biomimetic valve designs, new transcatheter aortic valve systems, novel devices for aortic insufficiency, leaflet resection, left atrial appendage closure, and short self-expanding TAVR valves with promising early results.
How do I confidently expand my drug-coated balloon practice?
21 May 2025 – From EuroPCR 2025
This EuroPCR 2025 session challenges the conventional approach to bifurcation PCI and dissection management. Learn why drug-coated balloons (DCB) may offer better long-term outcomes in cases where stents fall short, how DCBs can simplify bifurcation strategies, and why it’s time to rethink which dissections really need...
Paravalvular leak closure: challenges and percutaneous solutions
21 May 2025 – From EuroPCR 2025
This session addresses the challenges and percutaneous techniques for paravalvular leak closure following valve replacement. Through complex case studies, it explores managing unexpected anatomical defects, dealing with failed closure attempts, and strategies in malpositioned valves, providing practical guidance for successful intervention in difficult scenarios.
Through decisions in complex left main PCI - Isolated ostial left circumflex
21 May 2025 – From EuroPCR 2025
Navigate complex isolated ostial left circumflex lesions with a focus on the integration of imaging and physiological assessment. Learn treatment options and optimisation strategies to improve long-term outcomes in left main PCI through detailed case presentations and expert guidance.
Evolving bifurcation treatment practices: drug-coated balloons, angio-based FFR, and side branch optimisation
20 May 2025 – From EuroPCR 2025
Explore how bifurcation treatment is evolving with the integration of drug-coated balloons, angio-based FFR, and advanced side branch optimisation. This EuroPCR 2025 session highlights why DCB is gaining traction for bifurcation lesions and introduces the upcoming EBC-DCB trial comparing a stepwise DCB strategy to provisional DES...
Use of advanced coronary techniques in bailout of aortic valvuloplasty balloon entrapment
25 Mar 2025
Balloon entrapment in valvuloplasty can be life-threatening, especially after balloon rupture. Learn about a new technique involving balloon internalisation and safety snares for successful retrieval and sheath upsizing.
The top clinical cases in interventional cardiology
25 Nov 2024 – From PCR London Valves 2024
Curious about the latest in interventional cardiology? Don't miss this video!
You'll discover groundbreaking techniques for complex conditions, from treating mitral regurgitation after healed endocarditis to repairing the tricuspid valve in dextrocardia. You'll also see the latest advances (including the SAPIEN 3 Tendyne device) and gain expert...
Non-transfemoral TAVI - The toolkit
25 Nov 2024 – From PCR London Valves 2024
When should you consider alternative access for TAVI instead of the transfemoral route? This video dives right into the different non-transfemoral approaches, from transsubclavian to transcaval, and explains when each technique is most appropriate.
Learn how vascular modification can expand access options for more patients and discover...
Optimisation of your valve implantation to ensure lifelong outcomes using a novel self-expanding valve
24 Nov 2024 – From PCR London Valves 2024
Gain insights into the importance of valve optimization post-implantation to secure acute and long-term outcomes. In this session, you will discover the new features and benefits of the ACURATE Prime platform illustrated by a recorded case, and compare how different TAVI platforms perform when treating larger...
Breaking new ground in mitral valve interventions
24 Nov 2024 – From PCR London Valves 2024
What’s shaping the future of mitral valve therapies? This video from PCR London Valves 2024 unveils groundbreaking late-breaking trials that redefine the possibilities in mitral interventions.
You'll explore real-world insights from the OCEAN-Mitral registry on the MitraClip G4, uncover the link between tricuspid regurgitation and 3-year mortality...
Insights from the top late-breaking trials at PCR London Valves 2024
24 Nov 2024 – From PCR London Valves 2024
Looking to stay ahead in transcatheter valve therapies? Don't miss out this video showcasing the most impactful late-breaking trials from PCR London Valves 2024.
Discover pivotal findings, including one-year results comparing two balloon-expandable TAVI valves, outcomes of the TRISCEND II trial for tricuspid regurgitation and groundbreaking insights...
Stentless bifurcation PCI: what does the future hold?
25 Sep 2024
Watch the replay of this webinar on contemporary challenges in bifurcation PCI in case examples and so much more!
Imaging-guided left main PCI - LIVE case
Recommended by PCR
17 May 2024 – From EuroPCR 2024
A 53-year-old male with a history of advanced malignancy (lung adenoma) and mid LAD PCI last year, along with multiple risk factors (hypertension, dyslipidemia, diabetes, and smoking), presented with angina and a positive stress test and CT. The angiography and CT showed significant left main stenosis...
Complicated scenarios in LAA occlusion
15 May 2024 – From EuroPCR 2024
Explore this session to discover strategies for handling complications during and after LAA occlusion, examine scenarios where LAA occlusion can serve as a secondary intervention, and review complex cases like embolised occluders, combined MitraClip and LAA procedures, and unexpected events in patient management.
Go beyond metal: exploring drug-eluting balloon technology in de-novo coronary lesions
15 May 2024 – From EuroPCR 2024
Through the study of two cases, this session examines the need for stenting bifurcation lesions and the role of DEB technology in avoiding stent-related complications in long diffuse disease. It emphasizes the benefits of SELUTION SLR balloons for de novo lesions, discussing how sustained limus release...
