Francesco Burzotta

Francesco Burzotta

Interventional cardiologist / Cardiologist
Policlinico Universitario Agostino Gemelli - Roma, Italy

Latest contributions

Complex bifurcation PCI: LIVE Educational Case from Leipzig Heart Centre - Leipzig, Germany

21 May 2026 – From EuroPCR 2026

Through a live educational case from Leipzig Heart Centre, this session addresses the complexities of bifurcation PCI. It discusses criteria defining complex bifurcation lesions, management strategies for challenging side branch access, and evaluates treatment options for true bifurcation lesions. The session includes patient presentation, detailed imaging...

Complications during left main PCI: how to manage and how to avoid

20 May 2026 – From EuroPCR 2026

This session addresses the identification, prevention, and management of complications arising during left main percutaneous coronary intervention (PCI). Through detailed case presentations and analyses, it highlights anatomical and procedural risk factors, strategies to anticipate and recognize complications such as stent deformation and coronary perforation, and effective...

Choosing the right strategy for isolated ostial left anterior descending artery or circumflex coronary lesions

20 May 2026 – From EuroPCR 2026

This session examines optimal strategies for managing isolated ostial lesions in the left anterior descending and circumflex arteries, comparing left main crossover, ostial stenting, and drug-coated balloon (DCB) approaches. It emphasizes integrating multimodality imaging for informed decision-making, illustrated through detailed case discussions.

Evolving bifurcation treatment practices: DCB, angio-based FFR and side branch optimisation

19 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session explores the evolving landscape of bifurcation PCI, focusing on drug-coated balloon (DCB) strategies, angio-based fractional flow reserve (FFR) and side branch optimisation. It highlights how new evidence and physiology-guided tools are reshaping decision-making in this complex lesion subset.

Discussions include insights from the...

Evolving bifurcation treatment practices: DCB, angio-based FFR and side branch optimisation

Main vessel stenting in DK-Crush: lessons from stepwise provisional strategy

  • Optimisation of side branch stenting
  • How to optimally deploy the second stent

Commented by Goran Stankovic and William Wijns

Part 3 of a 3-part series. Previous episode: How to correct incomplete crush and how to prevent lack of carina coverage

Main vessel stenting in DK-Crush: lessons from stepwise provisional strategy

DK Crush like you’ve never seen it before

  • Multi-modality simulation to unveil the hidden parts & small obstacles that can result in complications
  • Angioscopy directly inside the coronary artery to provide a better understanding of 3D stent configuration

Commented by Goran Stankovic and William Wijns

Part 1 of a 3-part series.
Next episode: How to correct incomplete crush and...

DK Crush like you’ve never seen it before

Highlights of science and education in cardiovascular interventional medicine in 2025

22 Dec 2025

Dear Colleagues, dear PCR Companions,

As we welcome a New Year, it is the perfect time to reflect on what we achieved together over the past year - both as a celebration of our collective success and as motivation to continue improving in the year ahead.

2025 was...

PCI for complex bifurcation disease - LIVE Case

23 May 2025 – From EuroPCR 2025

A 60-year-old male patient presented with an inferior STEMI one month ago, which was treated with RCA and LCx PCI. He was referred for LAD/diagonal PCI. The LV function was reduced (EF 45 %). The team performed a DK crush PCI, guided by IVUS.

LIVE Educational Case...

PCI for complex bifurcation disease - LIVE Case

How to perform DK-Crush for left main bifurcation stenting

22 May 2025 – From EuroPCR 2025

Including: A clinical case performed live in Poznan, Poland, showing conventional guidance with angiography and intravascular imaging
Modern technology: machine learning, AI and 3D (multiple simulation techniques)

A series of 3 episodes

How to perform DK-Crush for left main bifurcation stenting

Through decisions in complex left main PCI – Left main trifurcation

22 May 2025 – From EuroPCR 2025

This session offers an in-depth analysis of complex left main trifurcation PCI, covering evaluation through imaging and physiology, lesion preparation strategies, and treatment options including stepwise provisional approaches, upfront two-stent techniques, and drug-coated balloons.

Through decisions in complex left main PCI – Left main trifurcation

High thrombus burden in STEMI

22 May 2025 – From EuroPCR 2025

This session addresses the management of high thrombus burden in STEMI patients. It reviews available tools and strategies for thrombus management, presents multiple case-based discussions illustrating treatment decisions, and explores the evolving role of thrombus aspiration in contemporary practice.

High thrombus burden in STEMI

How to correct incomplete crush and how to prevent lack of carina coverage

  • Differentiating between complete and incomplete crush
  • The importance of sequential crush and bigger balloons, adequately sized according to proximal vessel diameter

Commented by Goran Stankovic and William Wijns

Part 2 of a 3-part series:  
Previous episode: DK Crush like you’ve never seen it before
Coming up next: Main vessel stenting in DK-Crush, lessons...

How to correct incomplete crush and how to prevent lack of carina coverage

Left main and complex bifurcation stenting

22 May 2025 – From EuroPCR 2025

In this EuroPCR 2025 session, discover best practices for managing left main and challenging bifurcation lesions, from choosing a stepwise provisional side branch stenting strategy to using intracoronary imaging and physiology to guide and optimise PCI results.

Learn how the Ultimaster Nagomi™ sirolimus-eluting stent system builds on...

Left main and complex bifurcation stenting

Through decisions in complex left main PCI - Isolated ostial left circumflex

21 May 2025 – From EuroPCR 2025

Navigate complex isolated ostial left circumflex lesions with a focus on the integration of imaging and physiological assessment. Learn treatment options and optimisation strategies to improve long-term outcomes in left main PCI through detailed case presentations and expert guidance.

Through decisions in complex left main PCI - Isolated ostial left circumflex

How should I treat ostial left circumflex stenosis?

18 Feb 2025

Watch this webinar on Monday 3 March at 3:00pm (UTC+1) with G. Stankovic, M. Lesiak and F. Burzotta and learn how to evaluate left main 0,0,1 bifurcation lesion in terms of morphology and clinical relevance, and much more!

Imaging-guided left main PCI - LIVE case

17 May 2024 – From EuroPCR 2024

A 53-year-old male with a history of advanced malignancy (lung adenoma) and mid LAD PCI last year, along with multiple risk factors (hypertension, dyslipidemia, diabetes, and smoking), presented with angina and a positive stress test and CT. The angiography and CT showed significant left main stenosis...

Imaging-guided left main PCI

Non left main bifurcation - LIVE case

17 May 2024 – From EuroPCR 2024

A 53-year-old male presented with a late STEMI one month ago. Coronary angiography revealed three-vessel disease: CX occlusion (culprit lesion), RCA bifurcation stenosis, and severe mid LAD-D1 (1-1-1) stenosis. The operators performed RCA PCI during the STEMI hospitalization.
In this live case, they performed the LAD-D1 bifurcation...

Non left main bifurcation - LIVE case

How to approach isolated ostial left circumflex artery lesion?

15 May 2024 – From EuroPCR 2024

Thanks to this session, explore the role of imaging and physiology in assessing ostial circumflex lesions, examine treatment options for the ostial left circumflex artery, and discuss optimization strategies to enhance long-term outcomes.

How to approach isolated ostial left circumflex artery lesion?

Tools and technologies guiding decision making in bifurcation PCI

15 May 2024 – From EuroPCR 2024

In this session, discover that provisional stenting in routine non-LM bifurcation using Resolute Onyx DES yields good mid-term outcomes without side branch intervention, provided the stent is sized to the distal reference and the side branch remains patent after a systematic POT. Learn how bifurcation stenting...

Tools and technologies guiding decision making in bifurcation PCI

Left main and complex bifurcation stenting

14 May 2024 – From EuroPCR 2024

Watch this session focused on a patient with distal left main stenosis to understand that the stepwise provisional side branch (SB) stenting strategy is the standard approach for most left main trifurcation lesions. Discover the importance of optical frequency domain imaging for strategy determination and bifurcation...

Left main and complex bifurcation stenting

How to perform angiographic check after large-sheath removal in single access procedures

18 Mar 2024

In the absence of other arterial access, this step-by-step tutorial shows how to perform anterograde angiography of the arterial axis after removal of the large sheath, making it easier to recognise and rapidly manage vascular complications such as arterial lesions and haemostasis failure.

Francesco Burzotta

Author

Francesco Burzotta
Lazzaro Paraggio

Author

Lazzaro Paraggio
Mattia Lunardi

Author

Mattia Lunardi
Cristina Aurigemma

Author

Cristina Aurigemma
Enrico Romagnoli

Author

Enrico Romagnoli

Author

Francesco Fracassi

Author

Antonino Buffon
C. Trani

Author

Carlo Trani

How to perform simultaneous kissing balloon inflation with a single inflation device

05 Oct 2023

The idea is to simplify the clinical practice of kissing balloon inflation (KBI) by making this technique single-operator and automatically associated with simultaneous balloon deflation.

Francesco Burzotta

Author

Francesco Burzotta
Lazzaro Paraggio

Author

Lazzaro Paraggio
Cristina Aurigemma

Author

Cristina Aurigemma
Enrico Romagnoli

Author

Enrico Romagnoli

Author

Francesco Fracassi

Author

Antonino Buffon
C. Trani

Author

Carlo Trani

Left main and complex bifurcation stenting

18 May 2023 – From EuroPCR 2023

Want more training on bifurcation stenting? Learn from the case of this 75-year-old active man, a retired engineer, suffering from effort angina CCS 3 for 6 months, referred to the centre by his cardiologist for a coronary CT scan. He is a former smoker, has a...

Left main and complex bifurcation stenting

Can we use provisional stent strategy in complex bifurcation lesions?

18 May 2023 – From EuroPCR 2023

Watch this session to learn when a provisional stent strategy is appropriate for complex bifurcation lesions, discover optimization techniques for provisional stenting, and understand the scenarios that necessitate stenting the side branch.

Can we use provisional stent strategy in complex bifurcation lesions?

Bifurcation with provisional stent strategy - LIVE case

17 May 2023 – From EuroPCR 2023

Learn more about a 65-year-old diabetic male patient with BMI 31, NYHA III shortness of breath, and a mid-calcified lesion on proximal and mid-part of LAD. QFR and µFR were significant for the 2 LAD lesions (0.73 and 0.74). The proximal lesion was a bifurcation Medina 1-0-1...

Bifurcation with provisional stent strategy - LIVE case

Complex bifurcation PCI - LIVE case

17 May 2023 – From EuroPCR 2023

Study the case of this 69-year-old male patient with recent PCI on LAD presenting chronic coronary syndrome. Angiography showed calcified stenosis on bifurcation of proximal CX and large obtuse marginal 1, Medina 0-1-1.

The PCI strategy was an OCT-guided TAP technique: 

7F guiding catheter, predilatation with semi-compliant and non-compliant...

Complex bifurcation PCI - LIVE case

1st stent in left main PCI: simple but not too simple

03 Jan 2023

Watch the replay of the 1st webinar on bifurcation with Goran Stankovic. You’ll learn all about '1st stent in left main PCI'

TAVI challenges: session 1

27 Nov 2022 – From PCR London Valves 2022

Discover a series of TAVI challenges shared by your peers: a transfemoral TAVR through a severely tortuous and horizontal aorta in a morbidly obese patient, TAVI for pure non-calcified severe aortic regurgitation in a large annulus, peripheral access calcifications and more.

TAVI challenges: session 1

TAVI: vascular access and bleeding complications

27 Nov 2022 – From PCR London Valves 2022

To learn more about FAST ACCESS Pilot, transfemoral-only TAVI, next-generation suture-mediated closure device in TAVR, or percutaneous axillary TAVI under local anaesthesia, among others, watch this session from PCR LV 2022!

TAVI: vascular access and bleeding complications

How should I perform T and TAP to reduce the risks of metallic neo-carina?

22 Jul 2021

Watch the replay of this PCR Webinar with A. Banning F. Burzotta and G. Stankovic