
Latest contributions
TAVI for asymptomatic aortic stenosis after EARLY TAVI - TAVI and coronary artery disease after NOTION-3
21 May 2025 – From EuroPCR 2025
Critically assess the clinical implications of the EARLY TAVI and NOTION-3 trials with a focus on asymptomatic aortic stenosis and concomitant coronary artery disease. This session integrates recent evidence into patient-centered care pathways, offering case-based insights for optimizing timing and management strategies in TAVI patients.

New insights from the early and delayed aortic valve replacement implant patients: a sub-analysis of the Early TAVR trial
29 Mar 2025
Luigi Biasco provides his take on a sub-analysis of the Early TAVR trial about the early and delayed aortic valve replacement implant patients presented by Philippe Genereux at ACC.25 in Chicago.

Author

PCRonline @ ACC.25 Scientific Sessions
07 Feb 2025
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2025 Scientific Sessions #ACC25

Transcatheter aortic valve replacement for asymptomatic severe aortic stenosis: Results of the EARLY TAVR trial
29 Oct 2024
Luigi Biasco provides his take on the results of the EARLY TAVR trial, presented by Philippe Genereux at TCT 2024 in Washington.

Author

PCR @ TCT 2024 - Get the international perspective!
11 Oct 2024
Thanks to the contribution of a team of interventional cardiologists from around the globe, get the international perspective on Late-breaking Clinical Trials and Science released at TCT 2024 - check out the list below.

Unusual cases of PFO closure
15 May 2024 – From EuroPCR 2024
This session will feature selected EuroPCR 2024 Clinical Case submissions focused on unusual cases of patent foramen ovale (PFO) closure. Attendees will have the opportunity to explore challenging cases, such as unexplained hypoxemia in an elderly man post-lung cancer lobectomy, a case of persistent dyspnea and...

PCRonline @ ACC.24 Scientific Sessions
22 Mar 2024
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2024 Scientific Sessions #ACC24

TAVI versus SAVR in patients at low to intermediate risk: One year outcomes of the randomized DEDICATE-DZHK6 Trial
08 Apr 2024
Luigi Biasco interviews Moritz Seiffert about the one-year outcomes of the randomized DEDICATE-DZHK6 trial which he presented at ACC.24 in Atlanta.
TAVR was found non-inferior to SAVR in low-risk patients, showing decreased rates of death or stroke at one year. The trial supports TAVR's safety and efficacy, highlighting...

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Author

Artificial intelligence-derived risk score for mortality in secondary mitral regurgitation treated by transcatheter edge-to-edge repair: the EuroSMR risk score
13 Feb 2024
The study aim was to develop and validate a novel score for prediction of 1-year mortality and clinical outcomes through artificial intelligence (AI) application in patients undergoing M-TEER.

Reviewer

Reviewer

Mitral Late-Breaking Trials: CLASP IID, AltaValve transseptal programme, MitraSwiss in men and women, MiCLASP...
19 Nov 2023 – From PCR London Valves 2023
Discover the mitral late-breaking trials which were presented during PCR London Valves 2023:
- One-year outcomes of transcatheter mitral repair from the CLASP IID Registry
- AltaValve transseptal programme update
- Mitral TEER in men and women from MitraSwiss registry: is equality achieved?
- Combined impact of mitral valve gradients and mitral regurgitation reduction...

TRILUMINATE: Quality of life after transcatheter tricuspid-valve repair vs. medical therapy in severe TR
27 Oct 2023
Luigi Biasco interviews Suzanne V. Arnold about the results of the randomized TRILUMINATE pivotal trial which she presented during the TCT Congress 2023 in San Francisco

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PCRonline @ TCT 2023 - Get the international perspective!
17 Oct 2023
Thanks to the contribution of our team of interventional cardiologists from around the globe, view the international perspective on Late-breaking Clinical Trials and Science to be released at TCT 2023 - check out the list here!

PCRonline @ ESC Congress 2023: the interventional cardiology perspective!
07 Aug 2023
What was new and hot in interventional cardiology at #ESCCongress 2023!

NOTION 10 years - The nordic aortic valve intervention trial
28 Aug 2023
Luigi Biasco interviews Troels Højsgaard Jørgensen regarding the 10-year results of the NOTION trial which he presented at the ESC Congress 2023 in Amsterdam.
What can you learn about valve durability and life expectancy?

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Author

Impact of computational modeling on transcatheter left atrial appendage closure efficiency and outcomes: the PREDICT-LAA trial
24 Mar 2023
The results of PREDICT-LAA remain fascinating and point focus on a current topic such as the use of AI models in planning structural cardiac interventions.

Reviewer

Reviewer

Transcatheter vs surgical aortic valve replacement in aortic stenosis patients at low surgical risk: 3-year outcomes from the Evolut Low Risk trial
05 Mar 2023
Luigi Biasco provides his take on the clinical trial presented by John K. Forrest from Yale University School of Medicine, New Haven, Connecticut, USA during the 2023 ACC/WCC annual congress held in New Orleans, Louisiana.

Author

PCRonline @ ACC.23/WCC Scientific Sessions
23 Feb 2023
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology / World Heart Federation 2023 Scientific Sessions #ACC23 #WCCardio.

Edoxaban for thromboembolism prevention in pediatric patients with cardiac disease
30 Nov 2022
Pediatric patients requiring anticoagulation are a rare but extremely complex subgroup, with congenital (univentricular circulation, Fontan circulation, venous-to-systemic shunts) or acquired diseases (Kawasaki disease), which represents a therapeutic and logistic challenge.

Reviewer

PCRonline @ TCT 2022 - Get the international perspective!
12 Sep 2022
Thanks to the contribution of a team of interventional cardiologists from around the globe, view the international perspective on Late-breaking Clinical Trials and Science released at TCT 2022 - check out the list here!

Relative survival after mitral TEER in MitraSwiss patients
28 Aug 2022
Mirvat Alasnag interviews Luigi Biasco, first author of the MitraSwiss Registry which was presented at the ESC Congress 2022 in Barcelona. Together, they discuss the enrolled population, the inclusion criteria, the design and outcomes of MitraSwiss, its comparison with other European registries and the restoration of...

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Author

CLASP II D: A randomized comparison of TEER devices for degenerative mitral regurgitation
20 Sep 2022
Luigi Biasco interviews Scott Lim and Konstantinos P. Koulogiannis, Principal Investigators of CLASP IID.
The trial demonstrated safety and effectiveness of the PASCAL system and met non-inferiority endpoints, expanding transcatheter treatment options for prohibitive surgical risk patients with significant symptomatic degenerative mitral regurgitation.

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Balloon- versus self-expanding valve systems for treating small failed surgical aortic bioprostheses: the LYTEN trial
23 May 2022
Luigi provides us with the interventional cardiologist's point of view!
Currently, TAVR selection process is performed by matching the internal diameter of the surgically implanted bioprostheses to the external diameter of commercially available TAVR devices. Nonetheless, the impact of intrinsic design differences, such as supra vs intra-annular design,...

Reviewer

PCRonline @ ACC 2022 Scientific Sessions
29 Mar 2022
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2022 Scientific Sessions #ACC22.

One-year results of the Clasp TR Study: Transcatheter treatment of tricuspid regurgitation
22 Mar 2022
Alessandro Sticchi and Luigi Biasco provide their take on the 1-year results of the CLASP TR study which were presented by Dr Adan Greenbaum, co-director of the Emory Structural Heart and Valve Center (Atlanta, GA) during the 2022 American College of Cardiology annual Congress held in Washington D.C.

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Author

30-day outcomes following transfemoral transseptal transcatheter mitral valve replacement: Intrepid TMVR early feasibility study results
21 Jan 2022
The study by Zahr et al. reports the results of an interim analysis assessing procedural and clinical outcomes at 30-day in 15 patients treated with the newly developed Medtronic Intrepid 35-F trans-femoral transcatheter mitral valve replacement (TMVR) system.

Reviewer

Myocarditis after BNT162b2 mRNA vaccine against Covid-19 in Israel
26 Oct 2021
An active surveillance programme was initiated by the Israeli Ministry of Health to ascertain the possible causal relationship between the vaccine and myocarditis and evaluate incidence, clinical relevance, and related outcomes.

Reviewer

Amulet IDE: Amplatzer Amulet left atrial appendage occluder randomised controlled trial
31 Aug 2021
Luigi Biasco reports the best of Dj Lakkireddy (Overland Park, USA)'s presentation of the AMULET IDE trial at the Monday, August 30 Hot Line session of the ESC Congress 2021.

Author

PCRonline @ ESC Congress 2021: the interventional cardiology perspective!
21 Jul 2021
Make sure you stay up to date with what's new and hot in interventional cardiology at this year's #ESCCongress!

Moderate aortic stenosis in patients with heart failure and reduced ejection fraction
08 Jun 2021
The aim of this study was to determine the prognostic impact conferred by the presence of moderate AS on the outcomes of patients with HFrEF.

Reviewer
