Stable CAD (Coronary artery disease)

Latest stable coronary artery disease (stable CAD) content in interventional cardiology - research, practice, and education

A complex and changing disease state requiring wide expertise, stable CAD can involve a diverse range of underlying chronic or evolutionary stages involving full use of all available tools, devices and techniques like those for invasive imaging and functional assessment. Taking into account underlying comorbidities such as diabetes is critical. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks, all of which can be found here…

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PCRonline @ ACC.26 Scientific Sessions

12 Mar 2026

Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2026 Scientific Sessions #ACC26

PCRonline @ ACC.26 Scientific Sessions

Ticagrelor vs prasugrel in patients with diabetes and multivessel coronary artery disease: the TUXEDO-2 randomised clinical trial

17 Feb 2026

The TUXEDO-2 trial sought to directly compare prasugrel versus ticagrelor in diabetic patients undergoing percutaneous coronary intervention (PCI), with the aim of clarifying whether the non-inferiority of ticagrelor could be established.

Raffaele Piccolo

Reviewer

Raffaele Piccolo
TUXEDO-2 ticagrelor vs prasugrel in patients with diabetes and MVD CAD

Fractional flow reserve to guide revascularisation in patients with coronary artery disease undergoing TAVR

07 Jan 2026

The present analysis compared major adverse cardiac events in patients with significant coronary stenosis (FFR ≤ 0.80 or visual stenosis ≥ 90 %) versus those with non-significant stenosis (FFR > 0.80).

Ruxandra Sava

Reviewer

Ruxandra Sava
Alessandro Sticchi

Reviewer

Alessandro Sticchi
Fractional flow reserve to guide revascularisation in patients with coronary artery disease undergoing TAVR

Balloon lithotripsy added to conventional preparation before stent implantation in severely calcified coronary lesions

06 Jan 2026

In patients with severely calcified coronary lesions undergoing PCI, the BALI trial evaluated the benefit of the addition of intravascular lithotripsy to conventional lesion preparation on the composite endpoint of procedural failure and target vessel failure.

Nicola Ryan

Reviewer

Nicola Ryan
Balloon lithotripsy added to conventional preparation before stent implantation in severely calcified coronary lesions

NIRS-guided PCI: beyond calcium to precision PCI

11 Dec 2025 – From GulfPCR-GIM 2025

This session explores how near-infrared spectroscopy (NIRS) is redefining PCI by revealing what angiography cannot see. By identifying lipid-rich and vulnerable plaques, NIRS helps anticipate procedural risk and refine decision-making before stent implantation. The session shows how plaque composition, rather than calcium alone, can guide lesion...

NIRS-guided PCI: beyond calcium to precision PCI

Abstracts session 1

10 Dec 2025 – From GulfPCR-GIM 2025

This abstracts session presents contemporary research and clinical insights in interventional cardiology, covering topics such as colchicine therapy post-stenting, ranolazine use in chronic coronary syndrome, artificial intelligence applications in quantitative coronary analysis, and optimization techniques in transcatheter aortic valve implantation. It also explores novel predictors of...

Abstracts session 1

Challenging Cases

10 Dec 2025 – From GulfPCR-GIM 2025

This session presents a series of challenging cardiology cases that span a spectrum of clinical scenarios, including innovative approaches to hypertrophic obstructive cardiomyopathy management, rare coronary artery anomalies, fibrous lesions, and unusual acute coronary syndromes. These case studies highlight diagnostic complexities and therapeutic strategies essential for...

Challenging Cases

Impact of pullback pressure gradient on clinical outcomes after percutaneous coronary interventions

02 Dec 2025

While FFR traditionally reflects the severity of a lesion at a fixed location, PPG incorporates the pullback profile, enabling a more comprehensive understanding of disease distribution.

Emanuele Gallinoro

Reviewer

Emanuele Gallinoro
Nicola Ryan

Reviewer

Nicola Ryan
Impact of PPG on clinical outcomes after PCI

Renal, inflammation and protection strategies in PCI

11 Oct 2025 – From AICT-AsiaPCR 2025

Delve into renal protection and inflammation management strategies in PCI, with a focus on renal blood flow indicators in chronic heart failure, the protective role of exosomes in myocardial ischemia, and efficacy of renal guard devices against contrast-induced nephropathy. The session also examines radial artery occlusion...

Device-related complications and innovative solutions

10 Oct 2025 – From AICT-AsiaPCR 2025

Examine a comprehensive overview of device-related complications encountered during interventional cardiology procedures and the innovative solutions designed to overcome these challenges. This session features diverse case studies including stent dislodgement, aorto-ostial calcified vessel interventions, balloon entrapment, and rare anatomical fistula closures, illustrating practical management strategies.