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Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

Featured research - TAVI: Redo strategies, valve performance & access safety

17 Nov 2025 – From PCR London Valves 2025

This detailed session investigates critical aspects of TAVI procedures including the safety of selective and routine femoral access angiography post-TAVI, outcomes from the ReTAVI registry focusing on redo-TAVI in various valve frames, and a comparative analysis of JenaValve versus Evolut transcatheter heart valves in severe aortic...

Featured research - TAVI: Redo strategies, valve performance & access safety

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Transcatheter tricuspid valve replacement

16 Nov 2025 – From PCR London Valves 2025

This session reviews contemporary advances in transcatheter tricuspid valve replacement (TTVR). It highlights long-term follow-up data from tricuspid valve-in-valve cases, introduces the novel Vdyne valve device for tricuspid regurgitation, and discusses timing considerations for interventions following surgical aortic valve replacement. Additionally, it evaluates the role of...

Curious mitral and tricuspid scenarios

16 Nov 2025 – From PCR London Valves 2025

This session presents a series of challenging and unusual clinical scenarios involving mitral and tricuspid valve disease. Topics include management of acute primary mitral regurgitation in high-surgical-risk patients, technical challenges in transcatheter mitral valve replacement (TMVR), and complex cases where cardiac rhythm disturbances interplay with valvular...

Featured research: latest advances in mitral TEER and valve repair technologies

16 Nov 2025 – From PCR London Valves 2025

This session presents featured research on mitral valve interventions, including two-year outcomes from the MitraClip G4 EXPAND study, comparative data of mitral TEER versus redo surgery in failed surgical repair, evidence from novel TEER programs in non-surgical centers, and safety and efficacy results of the NeoNova...

Featured research: latest advances in mitral TEER and valve repair technologies

Featured research: innovations, safety and evolving pathways in modern TAVI care

16 Nov 2025 – From PCR London Valves 2025

This session addresses contemporary challenges in TAVI, including management of acute valve syndrome through service innovations and the application of Valvosoft non-invasive ultrasound therapy in severe aortic stenosis. It also explores complications such as infective endocarditis post-TAVI, evaluates the feasibility of same-day discharge protocols, and assesses...

Featured research: innovations, safety and evolving pathways in modern TAVI care

How to perform angiographic check after large-sheath removal in single access procedures

18 Mar 2024

In the absence of other arterial access, this step-by-step tutorial shows how to perform anterograde angiography of the arterial axis after removal of the large sheath, making it easier to recognise and rapidly manage vascular complications such as arterial lesions and haemostasis failure.

Francesco Burzotta

Author

Francesco Burzotta
Lazzaro Paraggio

Author

Lazzaro Paraggio
Mattia Lunardi

Author

Mattia Lunardi
Cristina Aurigemma

Author

Cristina Aurigemma
Enrico Romagnoli

Author

Enrico Romagnoli

Author

Francesco Fracassi

Author

Antonino Buffon
C. Trani

Author

Carlo Trani
How to perform angiographic check after large-sheath removal in single access procedures

Self-made steerable catheter to cross the aortic valve in severe aortic stenosis

15 Apr 2026

When standard catheters and wires repeatedly fail to cross a severely stenotic aortic valve, a simple modification of readily available equipment may provide a solution.

This step-by-step tutorial explains how to create and use a self-made steerable catheter system to facilitate valve crossing in complex TAVI anatomies.

Author

Osama Bisht
Won-Keun Kim

Author

Won-Keun Kim
Robert R. Flieger

Author

Robert R. Flieger
Self-made steerable catheter to cross the aortic valve in severe aortic stenosis

OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

08 Nov 2022

Ali Nazmi Calik provides his take on OPTION, which was presented during AHA 2022 in Chicago.

Author

Ali Nazmi Calik
OPTION – Indobufen or aspirin on top of clopidogrel after coronary drug-eluting stent implantation

The top ten impactful papers from 2025 on tricuspid intervention we almost missed

13 Jan 2026

Transcatheter interventions have rapidly reshaped the management of tricuspid valve disease, with landmark trials establishing feasibility and early clinical benefit.

Beyond these pivotal studies, a series of less visible but highly informative papers addressed mechanisms, complications, patient phenotypes, and unintended consequences of intervention.

This curated selection highlights ten impactful tricuspid...

Alessandro Sticchi

Author

Alessandro Sticchi
The top ten impactful papers on tricuspid intervention we almost missed

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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