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Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

Featured research - TAVI: Redo strategies, valve performance & access safety

17 Nov 2025 – From PCR London Valves 2025

This detailed session investigates critical aspects of TAVI procedures including the safety of selective and routine femoral access angiography post-TAVI, outcomes from the ReTAVI registry focusing on redo-TAVI in various valve frames, and a comparative analysis of JenaValve versus Evolut transcatheter heart valves in severe aortic...

Featured research - TAVI: Redo strategies, valve performance & access safety

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

Beyond TAVI

16 Nov 2025 – From PCR London Valves 2025

This session offers a glimpse into cutting-edge structural heart interventions beyond TAVI. It introduces novel devices in early development stages targeting aortic valve stenosis and leaflet modification, discusses strategies to facilitate or defer TAVI, and provides opportunities for engagement with early-stage start-up partners innovating in structural...

Transcatheter tricuspid valve replacement

16 Nov 2025 – From PCR London Valves 2025

This session reviews contemporary advances in transcatheter tricuspid valve replacement (TTVR). It highlights long-term follow-up data from tricuspid valve-in-valve cases, introduces the novel Vdyne valve device for tricuspid regurgitation, and discusses timing considerations for interventions following surgical aortic valve replacement. Additionally, it evaluates the role of...

Curious mitral and tricuspid scenarios

16 Nov 2025 – From PCR London Valves 2025

This session presents a series of challenging and unusual clinical scenarios involving mitral and tricuspid valve disease. Topics include management of acute primary mitral regurgitation in high-surgical-risk patients, technical challenges in transcatheter mitral valve replacement (TMVR), and complex cases where cardiac rhythm disturbances interplay with valvular...

Featured research: latest advances in mitral TEER and valve repair technologies

16 Nov 2025 – From PCR London Valves 2025

This session presents featured research on mitral valve interventions, including two-year outcomes from the MitraClip G4 EXPAND study, comparative data of mitral TEER versus redo surgery in failed surgical repair, evidence from novel TEER programs in non-surgical centers, and safety and efficacy results of the NeoNova...

Featured research: latest advances in mitral TEER and valve repair technologies

Featured research: innovations, safety and evolving pathways in modern TAVI care

16 Nov 2025 – From PCR London Valves 2025

This session addresses contemporary challenges in TAVI, including management of acute valve syndrome through service innovations and the application of Valvosoft non-invasive ultrasound therapy in severe aortic stenosis. It also explores complications such as infective endocarditis post-TAVI, evaluates the feasibility of same-day discharge protocols, and assesses...

Featured research: innovations, safety and evolving pathways in modern TAVI care

BYPASS-CTCA: The value of computed tomography cardiac angiography in improving patient satisfaction and reducing contrast load, procedural duration and complications in patients who had previous CABG undergoing invasive coronary angiography

19 Sep 2022

Nicola Ryan provides her take on the BYPASS-CTCA Study which was presented by Daniel A. Jones at the TCT Congress 2022.

It must be understood that the paper has yet to be published for this study therefore all assumptions are based upon the presented data.

Nicola Ryan

Author

Nicola Ryan
Trial Computed Tomography Cardiac Angiography Contrast Load Procedural Duration CABG Invasive Coronary Angiography

A large-scale, randomized trial of orbital atherectomy vs. conventional balloon angioplasty in severely calcified coronary arteries prior to DES implantation (ECLIPSE)

30 Oct 2024

Nicola Ryan provides her take on the ECLIPSE trial presented by Ajay J. Kirtane at TCT 2024 in Washington.

Nicola Ryan

Author

Nicola Ryan
A large-scale, randomized trial of orbital atherectomy vs. conventional balloon angioplasty in severely calcified coronary arteries prior to DES implantation (ECLIPSE)

UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial

19 Sep 2022

Ali Nazmi Calik provides his take on UNIVERSAL randomized clinical trial, which questioned whether routine ultrasonography guidance for CFA access for cardiac procedures reduces bleeding or vascular complications. This trial was presented by Sanjit S. Jolly during TCT 2022.

Author

Ali Nazmi Calik
UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial

When transfemoral TAVI is not an option: rethinking alternative access strategies

18 Jun 2026

In this article, Ulrich Schäfer explores the evolving landscape of access strategies in transcatheter aortic valve implantation (TAVI). While the transfemoral approach remains the gold standard, a significant proportion of patients are not suitable due to peripheral vascular disease or anatomical constraints.
Drawing on clinical evidence and...

Author

Ulrich Schaefer
Alternative access, if transfemoral is not working

HOST-EXAM:10-year follow-up of clopidogrel vs aspirin monotherapy in stable CAD after PCI with drug-eluting stent

30 Mar 2026

Nicola Ryan provides her take on the 10-year follow-up of the HOST-EXAM, which was presented by Hyo-Soo Kim at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
10-year follow-up of clopidogrel vs aspirin monotherapy in stable coronary artery disease after percutaneous coronary intervention with drug-eluting stent

Transcatheter edge-to-edge repair in patients with severe mitral regurgitation and cardiogenic shock: Insights from the TVT Registry

17 Sep 2022

Mirvat Alasnag provides her take on the TEER Shock study which was presented at TCT 2022 by Mohamad A. Alkhouli.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
Transcatheter Edge-to-Edge Repair in Patients With Severe Mitral Regurgitation and Cardiogenic Shock: Insights From the TVT Registry

Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes: The multicenter, randomized, blinded, IVUS-ACS Trial

09 Apr 2024

Marco Spagnolo and Daniele Giacoppo report the main results of the IVUS-ACS trial presented by Shao-Liang Chen, from the Nanjing First Hospital, Nanjing Medical University, Nanjing, in a Featured Clinical Research session at ACC.24 in Atlanta and simultaneously published in The Lancet.(1)

Daniele Giacoppo

Author

Daniele Giacoppo
Marco Spagnolo

Author

Marco Spagnolo
IVUS-guided vs angiography-guided PCI in acute coronary syndromes
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