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Challenging TAVI

16 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities encountered in transcatheter aortic valve implantation (TAVI) in challenging anatomical settings. It reviews management of bicuspid valves with calcification, horizontal aorta, coronary artery anomalies, and navigation of difficult angles. Case studies illustrate techniques to optimize commissural alignment and strategies to address...

Paravalvular leak closure - Part 1

17 Nov 2025 – From PCR London Valves 2025

This session focuses on paravalvular leak closure challenges and solutions. It features complex cases such as extraction of plugs jailed between mechanical valves, managing leaks associated with severe annular calcification, aorto-mitral curtain leaks, device embolisation post-TMVR, and device-related haemolysis after closure procedures.

TAVI: unusual complications

16 Nov 2025 – From PCR London Valves 2025

This session examines rare and unusual complications arising from TAVI procedures. Topics include early recognition and management of frozen leaflets, ventricular septal perforation post-valve-in-valve TAVI, acute leaflet dysfunction, aorto-ventricular fistula formation, and percutaneous closure techniques for fistulas involving the right coronary sinus and right ventricle, emphasizing...

TAVI valve-in-valve - Part 4

17 Nov 2025 – From PCR London Valves 2025

This advanced session addresses complex valve-in-valve TAVI procedures, including management of challenging cases involving combined valve-in-valve TAVI and thoracic endovascular aortic repair. It also discusses technical considerations such as retrieval of lost stents in the left main coronary artery and critical aspects of TAV-in-TAV selection, sizing,...

Nightmare mitral interventions

16 Nov 2025 – From PCR London Valves 2025

This session presents complex mitral valve intervention cases highlighting procedural challenges and innovative solutions. It includes management of embolised transcatheter mitral valve replacements (TMVR), bailout redo transcatheter edge-to-edge repair (TEER), complications such as acute hypoxia and atrial wall perforations, and the application of TAVI skills in...

Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

Featured research - TAVI: Redo strategies, valve performance & access safety

17 Nov 2025 – From PCR London Valves 2025

This detailed session investigates critical aspects of TAVI procedures including the safety of selective and routine femoral access angiography post-TAVI, outcomes from the ReTAVI registry focusing on redo-TAVI in various valve frames, and a comparative analysis of JenaValve versus Evolut transcatheter heart valves in severe aortic...

Featured research - TAVI: Redo strategies, valve performance & access safety

Tricuspid valve interventions in complex scenarios

16 Nov 2025 – From PCR London Valves 2025

This session explores tricuspid valve interventions in complex clinical scenarios, emphasizing emerging techniques such as electrosurgical laceration to enable TTVR, emergency TEER for papillary muscle rupture, and expanded options for difficult valve disease. It also addresses procedural challenges when conventional implantation maneuvers fail, transcatheter alternatives for...

SEISMIC-HF I - Exploring non-invasive methods for monitoring intracardiac filling pressures

16 Nov 2024

Luis Ortega provides his take on the SEISMIC-HF I study presented by Liviu Klein at AHA 2024, in Chicago.

Luis Ortega-Paz

Author

Luis Ortega-Paz
SEISMIC HF-I

ECMO-CS – Extracorporeal membrane oxygenation in the therapy of cardiogenic shock: primary results from the multicenter, randomized ECMO-CS trial

07 Nov 2022

Mirvat Alasnag provides her take on the ECMO-CS trial, which was presented during AHA 2022 in Chicago, and simultaneously published in Circulation. 

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
ECMO-CS – Extracorporeal membrane oxygenation in the therapy of cardiogenic shock: primary results from the multicenter, randomized ECMO-CS trial

The PRE18FFIR trial: Coronary Plaque Activity to Predict Recurrent Events

01 Sep 2022

Alex Sticchi provides his take on the PRE18FFIR trial: Prediction of recurrent events with 18F-Sodium Fluoride to identify ruptured and high-risk coronary artery plaques in patients with myocardial infarction.

Alessandro Sticchi

Author

Alessandro Sticchi
The PRE18FFIR trial: Coronary Plaque Activity to Predict Recurrent Events

Coronary OCT and CMR imaging to determine sex differences in underlying causes of myocardial infarction with no obstructive coronary arteries

29 Mar 2026

Nicola Ryan provides her take on the trial evaluating multi-modality imaging to determine underlying causes of MINOCA in women and men. The trial results were presented by Harmony R. Reynolds at ACC.26 in New Orleans and simultaneously published in Circulation.

Nicola Ryan

Author

Nicola Ryan
Coronary optical coherence tomography and cardiac magnetic resonance imaging to determine sex differences in underlying causes of myocardial infarction with no obstructive coronary arteries

UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial

19 Sep 2022

Ali Nazmi Calik provides his take on UNIVERSAL randomized clinical trial, which questioned whether routine ultrasonography guidance for CFA access for cardiac procedures reduces bleeding or vascular complications. This trial was presented by Sanjit S. Jolly during TCT 2022.

Author

Ali Nazmi Calik
UNIVERSAL: routine ultrasonography guidance for femoral vascular access for cardiac procedures - A randomized clinical Trial

The 2023 ESH Hypertension Guidelines revisit the role of renal denervation

05 Sep 2023

The 2023 European Society of Hypertension (ESH) guidelines were recently presented at the 32nd annual European Meeting on Hypertension and Cardiovascular Protection and simultaneously published in the Journal of Hypertension.1 While wide parts of the guidelines do not substantially differ from the previous 2018 European Society...

Lucas Lauder

Author

Lucas Lauder

Author

Felix Mahfoud
The 2023 ESH Hypertension Guidelines revisit the role of renal denervation

The AQUATIC trial: Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation

01 Sep 2025

Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

Author

Chiara De Biase
The AQUATIC trial [Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial]

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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