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TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

17 Nov 2025 – From PCR London Valves 2025

This session presents critical case analyses of complicated TAVI procedures, highlighting unexpected and severe intra-procedural events such as annular perforation, leaflet modification complications, coronary obstructions, and device failures. It emphasizes prevention strategies, bailout techniques, and acute management to prepare clinicians for handling TAVI-related emergencies effectively.

TAVI: nightmare in the cathlab - Annular perforation, coronary obstruction & balloon rupture

Featured Research - TAVI: valve positioning & aortic anatomy

17 Nov 2025 – From PCR London Valves 2025

This session presents pioneering research on transcatheter aortic valve implantation (TAVI), exploring key topics such as the rise of osteogenic progenitors post-TAVI, the impact of transcatheter aortic valve planar tilt on outcomes, and the comparative results of self- versus balloon-expandable valves in patients with dilated ascending...

Featured Research - TAVI: valve positioning & aortic anatomy

TAVI valve-in-valve - Part 4

17 Nov 2025 – From PCR London Valves 2025

This advanced session addresses complex valve-in-valve TAVI procedures, including management of challenging cases involving combined valve-in-valve TAVI and thoracic endovascular aortic repair. It also discusses technical considerations such as retrieval of lost stents in the left main coronary artery and critical aspects of TAV-in-TAV selection, sizing,...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

17 Nov 2025 – From PCR London Valves 2025

This session examines the feasibility and technical considerations of mitral transcatheter edge-to-edge repair (TEER) in complex anatomical and pathological scenarios. Topics include applications in Barlow's disease, fibro-elastic deficiency, congenital heart anomalies, Anderson-Fabry disease, and post-cardiac transplantation, providing valuable insights into expanding TEER indications and overcoming anatomical...

Challenging mitral TEER: Barlow's disease, fibro-elastic deficiency & abnormal valve morphology

TAVI in challenging scenarios

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and emergent scenarios in TAVI, featuring cases such as emergent transfemoral TAVI in failing homograft roots complicated by extensive aortic dissection, the use of BASILICA in high-risk left main occlusion terrain, and the aorto-mitral challenges during TAVR. It also covers innovative coronary...

TAVI in challenging annular anatomy

17 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities of performing TAVI in challenging annular anatomies. It features case studies such as TAVI-in-TAVI in a patient with Morquio syndrome, strategies for managing severe annular calcification including calcium cracking techniques, and the use of large-diameter Myval valves for very large annuli...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

17 Nov 2025 – From PCR London Valves 2025

This session examines valve-in-valve interventions in TAVI, highlighting management of concomitant left main disease, unique case narratives such as "The Highlander story," and the unpredictability inherent in these procedures. It also reviews successful transfemoral TAV-in-SAV interventions in acute heparin-induced thrombocytopenia and addresses treatment of degenerated sutureless...

TAVI Valve-in-Valve: Managing unexpected anatomical challenges

Unravel the complexity of multi-valve disease

17 Nov 2025 – From PCR London Valves 2025

This session unpacks the complexities inherent in multi-valve disease involving combined mitral and tricuspid regurgitation. It emphasizes diagnostic challenges, the critical role of invasive hemodynamics in decision-making, and strategies for optimal timing and staging of interventions, demonstrated through illustrative patient cases.

Learning from lived experience and contemporary evidence: shaping the treatment of women with heart valve disease

17 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth exploration of the lived experiences of women with valvular heart disease, emphasizing the unique challenges in detection, diagnosis, treatment, and follow-up. It integrates contemporary evidence and the forthcoming 2025 ESC/EACTS guidelines to offer practice-ready strategies tailored to the management of valvular...

Featured research - Tricuspid valve intervention: latest advanced insights

17 Nov 2025 – From PCR London Valves 2025

This featured research session delves into advanced insights on tricuspid valve interventions, focusing on the significance of right ventricular function and dimension in patient outcomes. It explores prognostic factors such as right ventricular loading mismatch, innovations like the clover technique in Pascal TEER, myocardial work recovery,...

Featured research - Tricuspid valve intervention: latest advanced insights

TAVI: complex vascular access

17 Nov 2025 – From PCR London Valves 2025

This session addresses the challenges of complex vascular access in transcatheter aortic valve implantation (TAVI). It discusses strategies for navigating difficult thoraco-abdominal aortic anatomies, managing double aortic arches, and overcoming hostile femoral access. Case studies illustrate meticulous planning and innovative solutions essential for successful TAVI in...

Left atrial appendage occlusion

17 Nov 2025 – From PCR London Valves 2025

This session focuses on the complexities and innovations in left atrial appendage occlusion (LAAO) procedures. It covers transesophageal ICE monitoring, challenges posed by existing atrial septal occluders, combined surgical and percutaneous approaches, and the practical experience with the Ultraseal device. These insights advance understanding of procedural...

Valve interventions in grown-up congenital heart disease

17 Nov 2025 – From PCR London Valves 2025

This session presents complex valve interventions in patients with grown-up congenital heart disease, showcasing innovative transcatheter approaches including combined TAVI and pulmonary valve implantation in high-risk patients. Cases highlight management strategies in elderly patients with concomitant conditions such as patent ductus arteriosus and severe left ventricular...

Featured research - TAVI: cutting-edge developments

17 Nov 2025 – From PCR London Valves 2025

This featured research session reviews cutting-edge developments in TAVI, addressing challenges and outcomes in young patients with bicuspid aortic valve stenosis, prognostic significance of concomitant valvular disease, and long-term results of prophylactic chimney stenting and prosthetic valve performance in bicuspid stenosis.

Featured research - TAVI: cutting-edge developments

Featured research - TAVI - Part 10

17 Nov 2025 – From PCR London Valves 2025

Delve into comprehensive analyses of TAVI procedural outcomes and innovations in this session. Topics include the impact of intercoronary angles on coronary overlap with Evolut valves, mechanisms behind superior outcomes with the latest balloon-expandable valves, and predictive modeling of hemodynamics using physics-enhanced digital twins. Additionally, sex-specific...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

Transcatheter tricuspid valve replacement - Part 3

18 Nov 2025 – From PCR London Valves 2025

This session explores advanced transcatheter tricuspid valve replacement techniques and outcomes. It features cases of TricValve dysfunction due to intrinsic regurgitation, pioneering 'chimney technique' implantation in complex patients, right heart remodeling post-intervention, and innovative solutions including percutaneous heterotopic bicaval valve implantation following pericardiectomy.

TAVI in challenging anatomies

18 Nov 2025 – From PCR London Valves 2025

This session focuses on the challenges of performing TAVI in complex anatomical settings. It covers issues such as valve compression, hypertrophic cardiomyopathy-related left ventricular responses, alternative management strategies during crises, and handling anatomical complexities like membranous septal aneurysm at the annulus and sinus of Valsalva in...

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

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