Focus on drug coated balloons: evidence and practice
In this special report, learn about The Essentials of DCBs
DCBs have undergone extensive development to meet the challenges of minimizing restenosis and maintaining vessel patency. Unlike stents, DCBs deliver an antiproliferative drug directly to the arterial wall without leaving a permanent implant. This approach has proven effective in treating small-vessel disease, in-stent restenosis, and de novo lesions, supported by a growing body of clinical evidence demonstrating sustained efficacy in reducing late lumen loss. Read more

Learning objectives
- To understand the technology behind DCB
- To know the published studies in the field
- To learn how, when and why to use DCB
Table of Contents
In this article, Bruno Scheller explores advances in local drug delivery, from drug-coated balloons to novel antiproliferative agents. These innovations aim to reduce restenosis, minimize permanent implants, and pave the way for patient-specific coronary artery disease treatments.
This tutorial by Valeria Paradies and Gianluca Mincione highlights key steps and best practices for performing DCB angioplasty, ensuring effective drug delivery and improving patient outcomes.
Authored by Hector Garcia-Garcia and Jorge Sanz-Sanchez, this article examines pivotal randomized clinical trials on drug-coated balloons in coronary artery disease. It highlights their role in managing in-stent restenosis, de novo small vessel lesions, and large vessel lesions while exploring future directions through ongoing trials.
A 73-year-old male with complex recurrent in-stent restenosis of the left main underwent an innovative treatment approach. Discover how Piotr Buszman and Mateusz Kachel tackled this challenging case.
Fernando Alfonso and Javier Cuesta discuss the growing role of drug-coated balloons as an alternative to stents in percutaneous coronary interventions. Highlighting advantages like reduced in-stent restenosis, they emphasize the need for robust clinical studies to refine DCB use.
This series aims to provide you with insights into DCB technology, its application in native vessel disease, and its role in managing complex coronary lesions and in-stent restenosis (ISR). Join us for expert discussions, clinical case reviews, and the latest evidence to enhance your practice.
This special report is available thanks to the support of Concept Medical.
PCR develops independent educational programmes.