PCRonline @ TCT Connect 2020

Condensed take-home messages from the #TCT2020 Scientific Sessions

TCT CONNECT - October 14-18, 2020

Mirvat Al Asnag, Francesco Costa, Carlos Collet, Romain Didier, Nicolas Dumonteil, Hector Garcia-Garcia, Daniele Giacoppo, Nicole Karam, Vijay Kunadian, Dejan Milasinovic and Luis Ortega-Paz provide their take on a selection of major Late-breaking Clinical Trials in Interventional Cardiology released at the 2020 Transcatheter Cardiovascular Therapeutics Scientific Sessions.

Late-breaking Clinical Trials covered:

• PROSPECT II: A Prospective Natural History Study Using NIRS-IVUS Imaging in Patients With Acute Myocardial Infarction, David Erlinge
• COMBINE (OCT–FFR): A Prospective Natural History Study Using OCT Imaging in Patients With Diabetes, Elvin Kedhi
• PROSPECT ABSORB: A Randomized Trial of Interventional Treatment of Vulnerable Plaques, Gregg Stone
• COMPARE CRUSH: A Randomized Trial of Prehospital Crushed vs Uncrushed Prasugrel in STEMI, with an interview of Georgios Vlachojannis
• TICO-STEMI: A Randomized Trial of Ticagrelor Monotherapy vs Ticagrelor With Aspirin in STEMI, Byeong-Keuk Kim
• SCOPE II: A Randomized Trial of Two Self-expanding TAVR Bioprostheses, Corrado Tamburino
• REFLECT II: A Randomized Trial of a Cerebral Embolic Protection Device During TAVR, Jeffrey Moses
• Disrupt CAD III: Safety and Effectiveness of Intravascular Lithotripsy for Treatment of Severe Coronary Calcification, Dean Kereiakes
• XIENCE 90/28: Assessment of Three-Month and One-Month DAPT After Everolimus-Eluting Stents in High-Bleeding Risk Patients, Roxana Mehran, Marco Valgimigli, with an interview of Roxana Mehran
• TARGET FFR: A Randomized Trial of Physiology-Guided PCI Optimization, Damien Collison
• DEFINE-FLOW: An Observational Study of Deferred Lesions After FFR and CFR Assessment, Nils Johnson
• SOLVE-TAVI: One-Year Outcomes of a Factorial Randomized Trial of Self-expandable vs Balloon-expandable TAVR and General vs Local Anesthesia, with an interview of Hans-Josef Feistritzer
• STS/ACC TVT Registry: Cerebral Embolic Protection and TAVR Outcomes, David J. Cohen
• OPTIMIZE: A Randomized Trial of a Novel, Ultra Low Profile Fixed-Wire DES, Dean Kereiakes
• IREMMI: Outcomes of MitraClip in Patients With Acute Mitral Regurgitation in AMI With and Without Cardiogenic Shock, Rodrigo Estevez-Loureiro
• TRANSIT: Treatment of Failed TAVR With TAVR, Luca Testa
• #TCTConnect 2020 Summary and take-home messages