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Controlled trial of high-risk coronary intervention with percutaneous left ventricular unloading (CHIP-BCIS3)

01 Apr 2026

Aaysha Cader interviews Divaka Perera on the CHIP-BCIS3 randomised trial, which evaluated whether elective left ventricular (LV) unloading during high-risk PCI improves outcomes in patients with severe LV dysfunction, extensive coronary disease, and complex procedures, as presented at ACC.26 in New Orleans.

Author

Aaysha Cader

Author

Divaka Perera
Controlled trial of high-risk coronary intervention with percutaneous left ventricular unloading (CHIP-BCIS3)

HOST-EXAM:10-year follow-up of clopidogrel vs aspirin monotherapy in stable CAD after PCI with drug-eluting stent

30 Mar 2026

Nicola Ryan provides her take on the 10-year follow-up of the HOST-EXAM, which was presented by Hyo-Soo Kim at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
10-year follow-up of clopidogrel vs aspirin monotherapy in stable coronary artery disease after percutaneous coronary intervention with drug-eluting stent

When a surgical valve needs a second life

27 Feb 2026

A 79-year-old patient previously treated with surgical aortic valve replacement was referred after an episode of acute cardiac decompensation. Although clinically stabilised, further evaluation revealed degeneration of the bioprosthesis, and mixed aortic valve pathology.

This case focuses on the diagnostic assessment and the strategic considerations guiding the...

Christina Grothusen

Author

Christina Grothusen
When a surgical valve needs a second life

Ivus or angiography guidance for PCI in complex coronary bifurcation lesions (DKCRUSH-VIII)

31 Mar 2026

Nicola Ryan provides her take on DKCRUSH-VIII, a randomised controlled trial comparing IVUS versus angiography guidance for PCI, predominantly using the DKCRUSH technique in patients with complex bifurcation lesions, as presented by Shaoliang Chen at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
DKCrush VIII: Ivus or angiography guidance for PCI in complex coronary bifurcation lesions

Intravascular ultrasound-guided or angiography-guided complex high-risk PCI – The IVUS CHIP trial

28 Mar 2026

Daniele Giacoppo reports and provides his perspective on the main results of the IVUS-CHIP trial, presented by Roberto Diletti from the Erasmus University Medical Center, Rotterdam, the Netherlands, during a Late-Breaking Trials session at the ACC.26 in New Orleans, and simultaneously published in the New England Journal of...

Daniele Giacoppo

Author

Daniele Giacoppo
Intravascular ultrasound guidance for complex high-risk indicated procedures – The Ivus Chip trial

Protect the head to head trial: Randomized comparison of emboliner embolic protection catheter vs. sentinel cerebral protection system during transcatheter aortic valve replacement

28 Mar 2026

Alex Sticchi interviews Adam B. Greenbaum on the PROTECT head-to-head trial, comparing the new full-body Emboliner device with the first-generation Sentinel during TAVR, as presented at ACC.26 in New Orleans.

Alessandro Sticchi

Author

Alessandro Sticchi
Adam Greenbaum

Author

Adam Greenbaum
Protect the head to head trial: Randomized comparison of emboliner embolic protection catheter vs. sentinel cerebral protection system during transcatheter aortic valve replacement

Transcatheter aortic valve implantation without routine percutaneous coronary intervention: A randomized controlled trial (PRO-TAVI Trial)

29 Mar 2026

Jonathan Curio provides his take on the PRO-TAVI trial presented by Michiel Voskuil at ACC.26 in New Orleans and simultaneously published in The Lancet.

Jonathan Curio

Author

Jonathan Curio
TAVI without routine PCI: PRO-TAVI randomized controlled trial

Redo-surgery versus transcatheter valve-in-valve for mitral bioprosthetic dysfunction: The SURVIV trial

03 Apr 2026

Yohei Ohno provides his takeaways from the results of the SURVIV trial, which were presented by Dimytri Siqueira during the ACC.26 in New Orleans.

Yohei Ohno

Author

Yohei Ohno
Redo-surgery versus transcatheter valve-in-valve for mitral bioprosthetic dysfunction: The SURVIV trial

FFR or 3d-quantitative coronary angiography-based vessel-FFR guided revascularisation – The FAST III trial

28 Mar 2026

Chiara De Biase provides her take on the FAST III Trial presented by Joost Daemen at ACC.26 in New Orleans. She reviews the comparison between vFFR and FFR, highlighting key findings and their impact on revascularisation strategies.

Author

Chiara De Biase
FAST III: FFR vs 3D-QCA vessel-guided revascularisation

A randomized, placebo-controlled trial of chronic total occlusion PCI in stable angina - ORBITA-CTO trial

03 Apr 2026

Kalaivani Mahadevan provides an in-depth analysis of the ORBITA-CTO trial: a first-ever randomised, double-blind, placebo-controlled trial evaluating CTO PCI in stable angina patients.
She also interviewed principal investigators Sarosh Khan and John Davies following the LBCT Scientific Session at ACC.26 in New Orleans and simultaneous publication in...

John Davies

Author

John Davies
Kalaivani Mahadevan

Author

Kalaivani Mahadevan
Sarosh Khan

Author

Sarosh Khan
ORBITA-CTO: Chronic total occlusion PCI in stable angina