84 results
The future of aortic valve replacement - From index procedure to lifetime management
28 Apr 2026
A 68-year-old woman presents with symptomatic aortic stenosis and tricuspid valve anatomy, with no significant comorbidities and no evidence of coronary artery disease. Given her strong preference for a less invasive strategy, the Heart Team considers a transcatheter approach.
How would you treat this patient—and in case...

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TRISCEND II: Two-year outcomes of transcatheter tricuspid valve replacement for severe tricuspid regurgitation
31 Mar 2026
Jonathan Curio provides his take on TRISCEND II trial results presented by Vinod H. Thourani at ACC.26 in New Orleans.

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ALL-RISE: A large-scale, global randomized trial of coronary physiology derived from conventional angiography compared with an invasive pressure wire-based approach to guide PCI
28 Mar 2026
Mirvat Al Asnag provides her take on the ALL-RISE randomised trial presented by Ajay J. Kirtane at ACC.26 in New Orleans.

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Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial
28 Mar 2026
During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

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IVUS-guided versus angiography-guided PCI in unprotected left main coronary artery disease – The OPTIMAL trial
31 Mar 2026
Ali Nazmi Calik provides his take on the results of the OPTIMAL trial presented by Luca Testa at ACC.26 in New Orleans.

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Two-year outcomes after transcatheter tricuspid repair without cross-over in the randomised TRI-FR trial
28 Mar 2026
Alex Sticchi interviews Erwan Donal on the 2-year outcomes of the TRI-FR randomised trial evaluating transcatheter tricuspid edge-to-edge repair (T-TEER) versus medical therapy alone, as presented at ACC.26 in New Orleans.

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Controlled trial of high-risk coronary intervention with percutaneous left ventricular unloading (CHIP-BCIS3)
01 Apr 2026
Aaysha Cader interviews Divaka Perera on the CHIP-BCIS3 randomised trial, which evaluated whether elective left ventricular (LV) unloading during high-risk PCI improves outcomes in patients with severe LV dysfunction, extensive coronary disease, and complex procedures, as presented at ACC.26 in New Orleans.

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HOST-EXAM:10-year follow-up of clopidogrel vs aspirin monotherapy in stable CAD after PCI with drug-eluting stent
30 Mar 2026
Nicola Ryan provides her take on the 10-year follow-up of the HOST-EXAM, which was presented by Hyo-Soo Kim at ACC.26 in New Orleans.

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When a surgical valve needs a second life
27 Feb 2026
A 79-year-old patient previously treated with surgical aortic valve replacement was referred after an episode of acute cardiac decompensation. Although clinically stabilised, further evaluation revealed degeneration of the bioprosthesis, and mixed aortic valve pathology.
This case focuses on the diagnostic assessment and the strategic considerations guiding the...

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Ivus or angiography guidance for PCI in complex coronary bifurcation lesions (DKCRUSH-VIII)
31 Mar 2026
Nicola Ryan provides her take on DKCRUSH-VIII, a randomised controlled trial comparing IVUS versus angiography guidance for PCI, predominantly using the DKCRUSH technique in patients with complex bifurcation lesions, as presented by Shaoliang Chen at ACC.26 in New Orleans.

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