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The future of aortic valve replacement - From index procedure to lifetime management

28 Apr 2026

A 68-year-old woman presents with symptomatic aortic stenosis and tricuspid valve anatomy, with no significant comorbidities and no evidence of coronary artery disease. Given her strong preference for a less invasive strategy, the Heart Team considers a transcatheter approach.
How would you treat this patient—and in case...

Dominik Buckert

Author

Dominik Buckert

Author

Alper Öner
Arif Khokhar

Author

Arif Khokhar
The Future of Aortic Valve Replacement - From Index Procedure to Lifetime Management

TRISCEND II: Two-year outcomes of transcatheter tricuspid valve replacement for severe tricuspid regurgitation

31 Mar 2026

Jonathan Curio provides his take on TRISCEND II trial results presented by Vinod H. Thourani at ACC.26 in New Orleans.

Jonathan Curio

Author

Jonathan Curio
TRISCEND II: Two-Year Outcomes Of Transcatheter Tricuspid Valve Replacement For Severe Tricuspid Regurgitation

ALL-RISE: A large-scale, global randomized trial of coronary physiology derived from conventional angiography compared with an invasive pressure wire-based approach to guide PCI

28 Mar 2026

Mirvat Al Asnag provides her take on the ALL-RISE randomised trial presented by Ajay J. Kirtane at ACC.26 in New Orleans.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
A large-scale, global randomized trial of coronary physiology derived from conventional angiography compared with an invasive pressure wire-based approach to guide percutaneous coronary intervention

Outcomes in patients with atrial fibrillation randomized to receive LAA closure or oral anticoagulation: Primary results of the CHAMPION-AF clinical trial

28 Mar 2026

During the first Late-Breaking Trial session of the 2026 ACC Congress held in New Orleans, Saibal Kar, principal investigator of the CHAMPION-AF trial, presented the 3-year results of this groundbreaking study, which were simultaneously published in the NEJM (DOI: 10.1056/NEJMoa2517213).

Luigi Biasco

Author

Luigi Biasco
CHAMPION-AF: LAAC vs oral anticoagulation in atrial fibrillation

IVUS-guided versus angiography-guided PCI in unprotected left main coronary artery disease – The OPTIMAL trial

31 Mar 2026

Ali Nazmi Calik provides his take on the results of the OPTIMAL trial presented by Luca Testa at ACC.26 in New Orleans.

Ali Nazmi Calik

Author

Ali Nazmi Calik
Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in unprotected left main coronary artery disease – The OPTIMAL trial

Two-year outcomes after transcatheter tricuspid repair without cross-over in the randomised TRI-FR trial

28 Mar 2026

Alex Sticchi interviews Erwan Donal on the 2-year outcomes of the TRI-FR randomised trial evaluating transcatheter tricuspid edge-to-edge repair (T-TEER) versus medical therapy alone, as presented at ACC.26 in New Orleans.

Alessandro Sticchi

Author

Alessandro Sticchi
Erwan Donal

Author

Erwan Donal
Two-year outcomes after transcatheter tricuspid repair without cross-over in the randomised TRI-FR trial

Controlled trial of high-risk coronary intervention with percutaneous left ventricular unloading (CHIP-BCIS3)

01 Apr 2026

Aaysha Cader interviews Divaka Perera on the CHIP-BCIS3 randomised trial, which evaluated whether elective left ventricular (LV) unloading during high-risk PCI improves outcomes in patients with severe LV dysfunction, extensive coronary disease, and complex procedures, as presented at ACC.26 in New Orleans.

Author

Aaysha Cader

Author

Divaka Perera
Controlled trial of high-risk coronary intervention with percutaneous left ventricular unloading (CHIP-BCIS3)

HOST-EXAM:10-year follow-up of clopidogrel vs aspirin monotherapy in stable CAD after PCI with drug-eluting stent

30 Mar 2026

Nicola Ryan provides her take on the 10-year follow-up of the HOST-EXAM, which was presented by Hyo-Soo Kim at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
10-year follow-up of clopidogrel vs aspirin monotherapy in stable coronary artery disease after percutaneous coronary intervention with drug-eluting stent

When a surgical valve needs a second life

27 Feb 2026

A 79-year-old patient previously treated with surgical aortic valve replacement was referred after an episode of acute cardiac decompensation. Although clinically stabilised, further evaluation revealed degeneration of the bioprosthesis, and mixed aortic valve pathology.

This case focuses on the diagnostic assessment and the strategic considerations guiding the...

Christina Grothusen

Author

Christina Grothusen
When a surgical valve needs a second life

Ivus or angiography guidance for PCI in complex coronary bifurcation lesions (DKCRUSH-VIII)

31 Mar 2026

Nicola Ryan provides her take on DKCRUSH-VIII, a randomised controlled trial comparing IVUS versus angiography guidance for PCI, predominantly using the DKCRUSH technique in patients with complex bifurcation lesions, as presented by Shaoliang Chen at ACC.26 in New Orleans.

Nicola Ryan

Author

Nicola Ryan
DKCrush VIII: Ivus or angiography guidance for PCI in complex coronary bifurcation lesions