PCR Trials: Ticagrelor versus Clopidogrel in ACS and invasive management (TICAKOREA)

EuroIntervention Journal

The objective of this study is to compare the safety and efficacy of ticagrelor with clopidogrel in patients with ACS.

Study: multicentre, open-label randomised trial
Population: patients with ACS (with or without ST-Elevation) and intended invasive R x (85%)
Endpoints: clinically significant bleeding (composite of major or minor bleeding according to PLATO) at 12 months
onclusion: ticagrelor was associated with a significant higher bleeding rate than clopidogrel in patients with ACS and intended invasive management

Authors

Park et al. Circulation. 2019;140:1865-77