Prof. Antonio Colombo

Antonio Colombo

Interventional cardiologist / Cardiologist
Istituto Clinico Humanitas - Rozzano, Italy

This respected operator is the master « thinking tinkerer ». Every patient is a source of inspiration. No dogma is robust enough not to be challenged. The lessons from his Seminal IVUS observation on the stent underdeployment remain the foundation of proper interventional technique.

Latest contributions

Preventing distal particles embolization after DCB angioplasty

21 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Aloke Finn and Antonio Colombo share their insights on a specific and often overlooked complication of drug-coated balloon (DCB) angioplasty: particulate embolization.

They begin by clarifying the distinction between this phenomenon and traditional distal embolization, explaining that particulate embolization is iatrogenic and device-related—it is...

Preventing distal particles embolization after DCB angioplasty

Transforming PCI: mastering the implementation of drug-eluting balloons

22 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session provides a comprehensive overview of drug-eluting balloons (DEBs) and their growing role in percutaneous coronary intervention (PCI). Gain a clear understanding of the clinical evidence and rationale supporting DEBs, including how these devices minimize metal implantation and effectively treat both standard and...

Transforming PCI: mastering the implementation of drug-eluting balloons

RevoEdge high pressure cutting balloon in PCI: innovate, cut, and conquer

20 May 2025 – From EuroPCR 2025

Discover how the next-generation RevoEdge high-pressure cutting balloon is transforming PCI with innovative design and proven clinical outcomes. This session presents a multicenter randomised trial and real-world case discussions, showcasing RevoEdge’s effectiveness in tackling resistant, complex lesions—including long, tortuous, and fibrotic cases. Learn practical tips, tricks,...

RevoEdge high pressure cutting balloon in PCI: innovate, cut, and conquer

Sirolimus coated balloon for coronary artery disease and peripheral artery disease treatment: the new frontier

20 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session delivers a comprehensive update on the MagicTouch sirolimus-coated balloon (SCB) and its expanding role in treating both coronary and peripheral artery disease (CAD/PAD). The session covers the extensive clinical trial program supporting MagicTouch as a versatile treatment option across multiple indications. It...

Sirolimus coated balloon for coronary artery disease and peripheral artery disease treatment: the new frontier

DCB in de novo lesions: new valid option?

20 May 2025 – From EuroPCR 2025

Explore the emerging role of drug-coated balloons (DCB) in treating de novo coronary lesions. This session discusses complexity management, comparisons with drug-eluting stents (DES), and the potential of DCBs as valuable alternatives, especially in high bleeding risk patients.

DCB in de novo lesions: new valid option?

Perspectives on drug coated balloons from EuroPCR 2024

16 May 2024 – From EuroPCR 2024

In this roundtable discussion, Azeem Latib and Antonio Colombo discuss the role of drug-coated balloons (DCBs) in their current practice, including their indications, the different types of DCBs, and how to choose between them. They also cover ongoing studies in the US aimed at bringing this...

Perspectives on drug coated balloons from EuroPCR 2024

Physiology guided post-DCB treatment to safely limit stenting. Validation in complex clinical settings with the optical Optowire III pressure guidewire

16 May 2024 – From EuroPCR 2024

Follow this session to discover how accurate resting index can inform decision-making for DCB in CTO patients and understand the role of physiology in a new PCI workflow for complex MVD. Thus, you will learn about a DCB intention-to-treat strategy guided by post-PCI coronary physiology in...

Physiology guided post-DCB treatment to safely limit stenting. Validation in complex clinical settings with the optical Optowire III pressure guide

First results of randomised trials on advanced plaque modification techniques and intracoronary imaging

16 May 2024 – From EuroPCR 2024

This session presents the first results of randomized trials investigating the use of advanced plaque modification techniques, such as rotational atherectomy, lithotripsy, and laser atherectomy, as well as the role of intracoronary imaging (OCT and IVUS) in guiding percutaneous coronary intervention (PCI). The session aims to...

First results of randomised trials on advanced plaque modification techniques and intracoronary imaging

Sirolimus-coated balloon: expanding the scope of indications for complex coronary artery disease treatment

14 May 2024 – From EuroPCR 2024

Watch this session to gain case-based insights on using DCBs in complex settings. Learn valuable tips and tricks for optimal DCB application, including the best timing and situations for their use. Discover how to effectively implement a hybrid strategy that combines DES and DCB when needed.

Sirolimus-coated balloon: expanding the scope of indications for complex coronary artery disease treatment

Bioadaptor RCT 2 years: could we further improve long-term CAD outcomes vs DES?

14 May 2024 – From EuroPCR 2024

Follow this exchange between Antonio Colombo, Stefan Verheye, and Davide Capodanno as they discuss the past, present, and future of drug-eluting stents. They address the current limitations, emphasizing the issue of vessel caging, and suggest improvements, particularly highlighting the new Bioadaptor with uncaging bioresorbable elements that...

Percutaneous coronary intervention versus coronary artery bypass grafting in patients with left main disease with and without diabetes: findings from a pooled analysis of 4 randomized clinical trials

30 Apr 2024

This analysis shows that diabetic patients undergoing revascularization face substantially higher 5-year rates of all-cause mortality, myocardial infarction, repeat revascularizations, and stroke compared to non-diabetic patients.

Alessandro Sticchi

Reviewer

Alessandro Sticchi
Prof. Antonio Colombo

Reviewer

Antonio Colombo

Current indications for DCB in de novo lesions

18 May 2023 – From EuroPCR 2023

If you are interested in learning more about drug-coated balloon angioplasty in de novo disease, don't miss this informative session, which incorporates real-life cases. The session begins with a comprehensive review of the top five papers published in the past year, focusing on this topic. Additionally,...

Current indications for DCB in de novo lesions

Restoring vessel physiology and function with Dynamx Bioadaptor - The holy grail of PCI

17 May 2023 – From EuroPCR 2023

Join this session to explore the revolutionary Dynamx Bioadaptor and its role in restoring vessel physiology and function. Learn about the specific patient and lesion characteristics that can be safely and effectively treated with this innovative device, gain confidence in the delivery and deployment techniques, understand...

Going down the road of coronary artery disease treatment: sirolimus-coated balloon and DES + DCB stent platform

16 May 2023 – From EuroPCR 2023

What better way to talk about sirolimus-coated balloons than with real-life clinical cases? In this session, study the case of a 78-year-old man with crescendo angina and inferior wall ischaemia, or a 48-year-old woman with crescendo angina, type 2 DM and anterior wall hypokinesia with mild...

Learning from the Masters: Antonio Colombo - why did I choose to become an interventional cardiologist?

31 Oct 2022

Discover our new series entitled "Learning from the Masters"!
The aim of this series is to contribute to the understanding of the NextGen of how the field has evolved over the past decades, as they look toward the future of interventional cardiology & cardiac surgery.

In this...

Learning from the Masters: Antonio Colombo - why did I choose to become an interventional cardiologist

Complex PCI with left ventricular support - Session with LIVE case

07 Oct 2022 – From AICT-AsiaPCR 2022

Look at this case of a 73-year-old man, heavy smoker, with hypertension, type 2 DM, and hyperlipidemia, who recently suffered class III effort-related angina and non-ST elevation MI, who presented with a totally occluded RCA, ulcerated LM, occluded LAD, and stenotic LCx, and study LIVE a complex PCI...

Complex PCI with left ventricular support

EuroPCR 2022 Hotlines / Late-Breaking Trials in Drug-eluting balloons: U-REDUCE STENT, HYPER, IMPROVED-CTO, and more!

19 May 2022 – From EuroPCR 2022

Find out more about various studies & registries in drug-eluting balloons! A Sirolimus-coated balloon with micro-reservoir technology in coronary lesions, utilisation of DEB guided by post-PCI pressure gradient, DEB in combination with DES in the treatment of diffuse coronary artery disease,DEB for in-stent restenosis and plaque...

EuroPCR 2022 Hotlines / Late-Breaking Trials in Drug-eluting balloons: U-REDUCE STENT, HYPER, IMPROVED-CTO, and more!

TAVI best practice: implementing cusp overlap and commissural alignment

19 May 2022 – From EuroPCR 2022

Watch this session to understand why commissural alignment should become a standard procedure, why cusp overlap is fundamental for self-expandable devices, and why simulation-based learning is an advanced way to reduce the learning curve.

TAVI best practice: implementing cusp overlap and commissural alignment

Nothing to fear - a guide to combine DCB and DES in hybrid PCI

19 May 2022 – From EuroPCR 2022

DCB in in-stent restenosis, DCB and DES, DCB in ACS, and a guide to use DCB in de novo lesions and bifurcations: this is the programme of this EuroPCR 2022 session devoted, not surprisingly, to drug-coated balloons.

Nothing to fear - a guide to combine DCB and DES in hybrid PCI

Redefining indications for drug-eluting balloons in complex PCI - The role of sustained limus release

18 May 2022 – From EuroPCR 2022

Thanks to this EuroPCR 2022 session, discuss how sustained limus release technology can broaden DEB indications, learn about the decision-making process on the use of DEB adjacent to DES in complex PCI, and review DEB specific implantation techniques to achieve optimal outcomes for the patient.

Redefining indications for drug-eluting balloons in complex PCI - The role of sustained limus release

Cre8 EVO: the "sweetest advancement" that a diabetic patient is waiting for

18 May 2022 – From EuroPCR 2022

Thanks to a mix between cases and live lectures and discussions, this EuroPCR 2022 session will enable you to review the challenges of a PCI and the one-year results of the SUGAR RCT in diabetes mellitus patients, and to understand how to maximise PCI outcomes, especially by using Cre8 EVO...

Cre8 EVO: the 'sweetest advancement' that a diabetic patient is waiting for

Innovative devices for innovative procedures

17 May 2022 – From EuroPCR 2022

This session focuses on innovations to invent or improve therapeutic modalities in the cath lab based on unmet needs in PCI, LAAO, CHF interventions, intravascular imaging and therapeutics, TAVI, and peripheral vascular interventions.

Innovative devices for innovative procedures

Sirolimus coated balloon and coronary artery disease: expanding the treatment indications

17 May 2022 – From EuroPCR 2022

Through a case presentation, as well as upcoming studies and rationale for the Food and Drug Administration, the aim of this EuroPCR 2022 session is to help you answer the following questions: how can the use of a sirolimus-coated DCB be expanded in new and challenging treatment indications? Why is...

Sirolimus coated balloon and coronary artery disease: expanding the treatment indications

Unusual case of STEMI - To stent or not to stent or any other alternative?

07 Mar 2022

A 70-year-old gentleman with background of hypertension and smoking presented with STEMI. Coronary angiogram showed ectasia in the mid and distal segment with heavy thrombus burden.

Sandeep Basavarajaiah

Author

Sandeep Basavarajaiah

How should I treat? - An innovative approach to treat diffuse disease

23 Feb 2022

An 81-year-old gentleman with a history of dyslipidemia, hypertension, presenting a new onset of angina and dyspnea in the last 2 years underwent exertional test which resulted positive for ischemia.

Alessandro Sticchi

Author

Alessandro Sticchi

Empowering DES performance in complex patients to maximise efficacy and safety outcomes

20 May 2021 – From EuroPCR 2021

Watch this session presented by Marco Valgimigli, Istvan Ferenc Edes, Antonio Colombo, Rafael Romaguera, Gennaro Sardella and Pieter Stella in order to identify the key elements and actions to be considered to maximise complex PCI outcomes in diabetes mellitus and high bleeding risks patients, to understand how re-PCI impacts...

Empowering DES performance in complex patients to maximise efficacy and safety outcomes

MagicTouch sirolimus coated balloon continues to be the choice of treatment for CAD

19 May 2021 – From EuroPCR 2021

Watch this session presented by Antonio Colombo, Aloke Finn, Sandeep Basavarajaiah, Gianluca Caiazzo and Bernardo Cortese in order to know where to use a DCB in today's clinical practice, to learn about real-world case-based experience and interesting data presentation from various registries and clinical studies, and to understand the technology...

MagicTouch sirolimus coated balloon continues to be the choice of treatment for CAD

The future of PCI seems bright - The MagicTouch sirolimus-coated balloon

18 May 2021 – From EuroPCR 2021

Watch this session presented by Antonio Colombo, Bernardo Cortese and Sandeep Basavarajaiah in order to understand the strategy behind using a DCB as a proper solution for CAD and the result and potential of using a Sirolimus DCB in coronary intervention, as well as to get insights into real...

The future of PCI seems bright - The MagicTouch sirolimus-coated balloon

The latest on the prevail drug-coated balloon

18 May 2021 – From EuroPCR 2021

Watch this session presented by Azeem Latib and Antonio Colombo in order to reflect on the latest information on Prevail DCB and study, to explore DCB technology and hear the expert-recommended indications, and to gain insights through an interesting PI case using Prevail DCB.

The latest on the prevail drug-coated balloon

The impact of COVID-19 pandemic on interventional cardiologists in training

23 Oct 2020

In collaboration with EuroIntervention Journal

The authors decided to create a survey tailored for ICTs in order to assess the changes in their training. Capturing the essence of the responses may help to identify the most appropriate strategies to provide the highest standards and skills achievements in COVID-19...