Ole De Backer

Ole De Backer

Interventional cardiologist / Cardiologist
Rigshospitalet - Copenhagen, Denmark

Latest contributions

All about PCR’s Teaching Assessment Board (TAB)

03 Dec 2025

Learn how session feedback is compiled to create a virtuous cycle of continuous refinement for education in #interventionalcardiology

When the first TAVI fails: no panic, just planning

02 Dec 2025

An 81-year-old man with history of severe aortic stenosis previously treated with a balloon-expandable transcatheter valve was referred for progressive exertional dyspnea due to bioprosthetic valve degeneration.

How would you treat this patient?

Barbara Bellini

Author

Barbara Bellini

Iatrogenic atrial septum defect closure: a necessary procedure?

18 Nov 2025 – From PCR London Valves 2025

This session addresses the clinical considerations surrounding iatrogenic atrial septal defects (ASDs) resulting from transseptal procedures. It covers prevention of residual defects, diagnostic evaluation, criteria for closure, procedural timing, and management strategies for related complications, supported by illustrative clinical cases demonstrating decision-making nuances.

Single operator TAVI: where expertise meets consistency

18 Nov 2025 – From PCR London Valves 2025

This session addresses the concept of single operator transcatheter aortic valve implantation (TAVI), emphasizing the integration of expertise with procedural consistency. Follow a discussion on the benefits of simplifying TAVI to a single operator approach facilitated by an electronically enabled delivery system. The session offers a...

Single operator TAVI: where expertise meets consistency

Exceptional engineering, predictable outcomes - Latest development of the VitaFlow TAVI device

17 Nov 2025 – From PCR London Valves 2025

Discover the latest advancements in the VitaFlow transcatheter aortic valve implantation (TAVI) device. This session highlights the electronically enabled VitaFlow Liberty system, delivering consistent immediate and mid-term clinical results. Watch real-world demonstrations of complex cases, including heavily calcified aortas and pure aortic regurgitation, and get a...

Exceptional engineering, predictable outcomes - Latest development of the VitaFlow TAVI device

Planning a lifetime of care in younger patients with Evolut FX+: from index valve to future options

17 Nov 2025 – From PCR London Valves 2025

Watch this PCR London Valves 2025 session to take a deep look at the latest evidence in low-risk aortic stenosis, the durability of contemporary valves, and how anatomy — especially in women and patients with small annuli — shapes long-term strategy.

From index TAVI with Evolut FX+...

Planning a lifetime of care in younger patients with Evolut FX+: from index valve to future options

Complications of LAA closure - Avoidance and management

17 Nov 2025 – From PCR London Valves 2025

Focused on the prevention and management of complications in left atrial appendage (LAA) closure, this session covers recognition of key procedural risks, techniques for safe transseptal puncture, and strategies to prevent and address device embolisation, pericardial effusion, residual leaks, and device-related thrombus, ensuring procedural safety and...

Complications of LAA closure - Avoidance and management

Prevention and management of TAVI complications

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to the prevention and management of complications associated with transcatheter aortic valve implantation (TAVI). Participants gain critical knowledge on managing vascular access challenges, anticipating and preventing valve malposition, handling device embolism, and evaluating coronary obstruction risks with effective prevention and bailout strategies.

Prevention and management of TAVI complications

Mitral TEER and LAA closure - LIVE case

17 Nov 2025 – From PCR London Valves 2025

This educational session presents a live case from Clinique Pasteur, Toulouse, France, focusing on Mitral Transcatheter Edge-to-Edge Repair (TEER) combined with Left Atrial Appendage (LAA) closure. Attendees gain insights into patient evaluation, operator strategies, device selection, and procedural execution, complemented by a recorded case from Upper...

Mitral TEER and LAA closure: LIVE Educational Case from Clinique Pasteur - Toulouse, France

Align for the future with next gen Myval transcatheter heart valve series

16 Nov 2025 – From PCR London Valves 2025

Discover how the latest Myval transcatheter heart valve (THV) innovations are shaping TAVI outcomes. This PCR London Valves 2025 session highlights the clinical evidence behind the next-gen Myval THV series, best practices for implantation, and upcoming innovations set to improve patient care. Learn step-by-step techniques for deploying Myval...

Align for the future with next gen Myval transcatheter heart valve series

Getting the full potential of the supra-annular valve in a changing landscape

16 Nov 2025 – From PCR London Valves 2025

This session explores the evolving landscape of transcatheter aortic valve implantation (TAVI) with a focus on supra-annular valve technology. It covers techniques for achieving commissural alignment, considerations for small aortic annuli, and advantages in treating bicuspid aortic valve disease, supported by clinical data and illustrative cases.

Getting the full potential of the supra-annular valve in a changing landscape

Valve selection in urgent TAVI: evidence from small annulus studies - Hotline

16 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research comparing self-expanding and balloon-expandable valves in urgent and emergent TAVI settings, with a focus on small aortic annuli. It includes data from the NAVULTRA and LANDMARK trials, featuring novel biomimetic balloon-expandable valves and early feasibility studies that shed light on valve...

Hotline - TAVI - Part 2

LAAC: current and future indications

03 Jun 2025

Watch the replay of this webinar and learn about the evidence (current guidelines and indications) for LAAC in 2025, and so much more!

Combined LAA closure and transcatheter mitral valve repair - LIVE Case

22 May 2025 – From EuroPCR 2025

An 82-year-old male patient with a history of PM (pacemaker) implantation in 2024, and ischaemic cardiomyopathy presented with symptomatic heart failure due to severe secondary mitral regurgitation and impaired LV function (EF 40 %). He also presented with recurrent gastro-intestinal bleeding while on DOAC for atrial...

Combined LAA closure and transcatheter mitral valve repair - LIVE Case

All you need to know on aorto iliac disease during TAVI: from access to complications management

22 May 2025 – From EuroPCR 2025

Gain expertise in managing aorto-iliac disease during TAVI procedures, from access planning to complication management. This session covers key imaging techniques, decision-making regarding stenting and lesion modification, approaches to access-related complications, and criteria for involving vascular surgeons, ensuring procedural safety and success.

All you need to know on aorto iliac disease during TAVI: from access to complications management

Successful finale - Latest best practices and technologies for large hole arterial and venous closure

22 May 2025 – From EuroPCR 2025

This session covers the latest best practices and technologies for large hole arterial and venous closure, focusing on minimising vascular complications.

Learn about a novel patch-based closure system with encouraging early results in TAVI cases, highlighting the importance of deployment angle and ultrasound guidance.

The venous case presentation...

Successful finale - Latest best practices and technologies for large hole arterial and venous closure

Which valve is best for my patient?

21 May 2025 – From EuroPCR 2025

This session guides clinicians in selecting the most appropriate transcatheter aortic valve tailored to individual patient characteristics. Through diverse case discussions, including patients with coronary artery disease, small anatomies, bicuspid valves, and surgical bioprostheses, it elucidates decision-making processes and planning for complex TAVI anatomies.

Which valve is best for my patient?

Innovations in TMVR and Intrepid trial updates

21 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session highlights the evolving role of transcatheter mitral valve replacement, focusing on the clinical potential of mitral regurgitation elimination. Get an overview of the current status of the Intrepid TMVR programme, learn about the transition to the 29Fr transfemoral system, and explore how...

Innovations in TMVR and Intrepid trial updates

Hotline TAVI 1: extended analysis of the randomised trials

21 May 2025 – From EuroPCR 2025

Gain comprehensive insights from extended analyses of randomized TAVI trials. This session reviews five-year UK TAVI outcomes, cardiac damage evolution in asymptomatic aortic stenosis, one-year results from the LANDMARK trial, and three-year comparisons of balloon-expandable valves, highlighting critical clinical implications.

Hotline TAVI 1: extended analysis of the randomised trials

Case-based learning on different aspects of transcatheter LAA closure

21 May 2025 – From EuroPCR 2025

Engage in case-based learning focused on transcatheter left atrial appendage (LAA) closure. This session covers safe transseptal puncture techniques, state-of-the-art standard LAA closure procedures, management of challenging LAA anatomies, and optimization of post-procedure antithrombotic therapy in high-risk patients.

Case-based learning on different aspects of transcatheter LAA closure

Challenges and solutions in an expanding TAVI world

20 May 2025 – From EuroPCR 2025

This EuroPCR 2025 session addresses key challenges and emerging solutions in today’s rapidly evolving TAVI landscape. It presents the latest evidence on valve replacement in low-risk patients with aortic stenosis, alongside strategies for navigating the complexities of lifetime management in TAVI candidates. The programme features a...

Challenges and solutions in an expanding TAVI world

Learnings from Evolut Low Risk 5-year and SMART 2-year trials : from evidence to practice

21 May 2025 – From EuroPCR 2025

At EuroPCR 2025, Angela McInerney, Didier Tchétché, and Ole De Backer discuss key results from the SMART and Evolut Low Risk trials. The SMART trial compared balloon-expandable and self-expanding valves in small annulus patients, showing better hemodynamics with the Evolut platform at 2 years. The Evolut...

Learnings from Evolut Low Risk 5-year and SMART 2-year trials : from evidence to practice

What are the essential aspects of transcatheter LAA closure?

20 May 2025 – From EuroPCR 2025

Ole De Backer and Philippe Garot discuss the rapid evolution of transcatheter left atrial appendage (LAA) occlusion.

They begin by contrasting patient selection in Europe and the US, where approaches diverge significantly: in Europe, very high bleeding risk remains the main criterion, while in the US, LAA...

What are the essential aspects of transcatheter LAA closure?

Heart to Heart Conversations podcasts – expert insights in interventional cardiology, anytime, anywhere

06 Feb 2025

Stay ahead in interventional cardiology with Heart-to-heart podcasts, the audio companion to our acclaimed webinar series.

Transcatheter mitral intervention for failed surgical valves and rings - The toolkit

26 Nov 2024 – From PCR London Valves 2024

Looking to enhance your approach to failed surgical mitral valves and rings? This video is a must-watch!

You’ll explore patient selection, master the steps of mitral valve-in-valve and valve-in-ring procedures, and learn strategies like valve cracking and LAMPOON to overcome key challenges. 

Transcatheter mitral intervention for failed surgical valves and rings - The toolkit

Pushing the boundaries to optimise patient outcomes: from planning to success

26 Nov 2024 – From PCR London Valves 2024

Learn from experts about achieving optimal TAVI outcomes, tailoring approaches for lifetime management, and mastering tips for diverse anatomical challenges.

Pushing the boundaries to optimise patient outcomes: from planning to success

Optimising TAVI for bicuspid aortic stenosis: experience with a novel self-expanding system

26 Nov 2024 – From PCR London Valves 2024

Watch this session to explore the latest trial results and insights on treating bicuspid aortic stenosis with self-expanding valves. Learn key tips for optimal outcomes, including the importance of supra-annular assessment, appropriate sizing, and techniques to prevent underexpansion. Discover the VitaFlow specifications and clinical data, including...

Optimising TAVI for bicuspid aortic stenosis: experience with a novel self-expanding system

What is the optimal TAVI access approach in contemporary practice?

14 May 2025 – From PCR London Valves 2024

What is the optimal TAVI access approach in today’s practice? Ole De Backer and Maarten Vanhaverbeke break down the latest evidence and trends in TAVI access. Watch this video to learn about the dominance of transfemoral access, the role of alternative routes like transcarotid and transaxillary,...

What is the optimal TAVI access approach in contemporary practice?

TAVI for aortic regurgitation

25 Nov 2024 – From PCR London Valves 2024

Curious about advancing your knowledge in TAVI for aortic regurgitation? Don’t miss this video!

You'll dive into the diagnostic and treatment strategies to optimize outcomes in patients with aortic regurgitation, explore groundbreaking technologies like the Jenavalve Trilogy THV system and gain insights from the latest clinical evidence and...

TAVI for aortic regurgitation

Transcatheter mitral valve replacement - Are we there yet?

25 Nov 2024 – From PCR London Valves 2024

Are we ready to embrace transcatheter mitral valve replacement (TMVR) as the next big step in mitral interventions? Find out in this must-watch video!

Discover the key anatomical factors that favor TMVR over TEER, get acquainted with cutting-edge TMVR platforms like Tioga, Cephea and Intrepid, and master...

Transcatheter mitral valve replacement - Are we there yet?