Ole De Backer

Ole De Backer

Interventional cardiologist / Cardiologist
Rigshospitalet - København, Denmark

Latest contributions

TAVI Essentials: From patient selection to procedural success

29 Jun 2026

Led by Ole De Backer, Christian Frerker and Alper Öner: a comprehensive expert-driven report covering the state of the art in aortic stenosis treatment.

Real world practice inspiring new evidence generation in structural heart

21 May 2026 – From EuroPCR 2026

This LIVE case session showcases real-world clinical practice driving new evidence in structural heart interventions, with a focus on TAVI. It features expert insights into pre-procedural imaging and sizing, treatment strategies, procedural techniques, and post-procedural management. The session also introduces the novel Myval Octapro+ transcatheter heart...

Real world practice inspiring new evidence generation in structural heart

Combined mitral repair and LAA closure with two separate septal punctures - LIVE case

21 May 2026 – From EuroPCR 2026

A 79‑year‑old man with hypertension, a history of basal cell carcinoma and psoriasis, presented with symptomatic severe primary MR (flail P2 due to ruptured chordae) and bleeding complications (recurrent skin bleeding) while on DOAC therapy for permanent atrial fibrillation.

Two G5 MitraClip devices were implanted. Subsequently, through...

Combined mitral repair and LAA closure with two separate septal punctures - LIVE case

TAVI: head-to-head trials

20 May 2026 – From EuroPCR 2026

This session presents head-to-head comparisons of TAVI devices from recent randomized trials and registries. Highlights include three-year outcomes from the SMART trial, two-year data from the LANDMARK trial on contemporary valves, comparisons of intra- and supra-annular self-expanding valves, evaluations in large annuli, the ALLEGRA trial focusing...

TAVI: head-to-head trials

Lessons learned to pave the way for future-proof strategies in TAVI

20 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session focuses on how current experience in transcatheter aortic valve implantation (TAVI) can be translated into more durable strategies for the future, particularly in patients with bicuspid aortic valve disease.

It provides a comprehensive overview of anatomical, clinical, and procedural considerations in this challenging...

Lessons learned to pave the way for future-proof strategies in TAVI

Insight from recent evidence in structural heart disease: indications for LAA closure (CHAMPION) and PCI in TAVI candidates (PRO-TAVI)

20 May 2026 – From EuroPCR 2026

This session reviews recent evidence impacting the management of structural heart disease, focusing on left atrial appendage (LAA) closure indications and PCI considerations in transcatheter aortic valve implantation (TAVI) candidates. It discusses optimal strategies for coronary artery disease in TAVI patients and evaluates findings from the...

Insight from recent evidence in structural heart disease: indications for LAA closure (CHAMPION) and PCI in TAVI candidates (PRO-TAVI)

PCR Global Interventional Academy

20 May 2026

This one-of-a-kind academy offers independent, cutting-edge training pathways for ambitious interventionalists who have been in practice for a few years and are looking to grow - both personally and professionally. Two recurrent high-level one-year tracks on coronary interventions and TAVI are already underway, with further opportunities forecast for...

Align for the future with structural heart innovations - LIVE case and major trial updates

19 May 2026 – From EuroPCR 2026

Stay abreast of structural heart innovations with expert discussions on best-in-class transcatheter aortic valve implantation (TAVI) practices, including imaging, sizing, and procedural strategies. This session with LIVE case introduces the novel Myval Octapro+ transcatheter heart valve (THV), its design philosophy, and potential clinical benefits, along with...

Align for the future with structural heart innovations - Live case and major trial updates

What is the latest in the management of coronary artery disease in TAVI candidates?

20 May 2026 – From EuroPCR 2026

Ole De Backer and Daniel Blackman discuss the management of coronary artery disease in TAVI candidates and whether PCI should be performed before valve implantation or safely deferred.

They review PROTAVI, which supports a selective strategy with PCI only when clinically indicated, with a signal toward less...

PCI before TAVI or not?

How to plan and perform TAVI in more challenging tricuspid AS anatomies?

12 May 2026

Watch this replay to learn how to anticipate anatomical challenges and optimize TAVI planning in complex tricuspid AS cases.

High calcium, high stakes: managing severe AS with complex multivessel disease

12 May 2026

A 69-year-old woman with severe symptomatic aortic stenosis (NYHA III) and complex comorbidities, including three-vessel coronary artery disease, advanced COPD, and peripheral artery disease, presents with progressive dyspnoea despite recent PCI. How would you treat this patient?

Author

Matti Adam

Author

Ole De Backer
Won-Keun Kim

Author

Won-Keun Kim

Revisiting aortic valve replacement in light of the new ESC/EACTS guidelines

04 Mar 2026

Dive into a webinar uncovering how cardiac CT is transforming the evaluation and lifetime management of severe aortic stenosis—from sharper diagnostics to smarter valve choices.

Interdisciplinary therapeutic strategy in a low-risk patient with aortic stenosis and preserved life expectancy

05 Mar 2026

A 71-year-old low-risk patient with symptomatic severe aortic stenosis and preserved ventricular function presents with progressive dyspnoea and chest pain. With long life expectancy, the choice of treatment demands careful interdisciplinary planning. How would you treat?

Conradi Lenard

Author

Lenard Conradi

Author

Ole De Backer

Author

Alper Öner
Thomas Pilgrim

Author

Thomas Pilgrim

All about PCR’s Teaching Assessment Board (TAB)

03 Dec 2025

Learn how session feedback is compiled to create a virtuous cycle of continuous refinement for education in #interventionalcardiology

When the first TAVI fails: no panic, just planning

19 Jan 2026

An 81-year-old man with history of severe aortic stenosis previously treated with a balloon-expandable transcatheter valve was referred for progressive exertional dyspnea due to bioprosthetic valve degeneration.

How would you treat this patient?

Barbara Bellini

Author

Barbara Bellini

Iatrogenic atrial septum defect closure: a necessary procedure?

18 Nov 2025 – From PCR London Valves 2025

This session addresses the clinical considerations surrounding iatrogenic atrial septal defects (ASDs) resulting from transseptal procedures. It covers prevention of residual defects, diagnostic evaluation, criteria for closure, procedural timing, and management strategies for related complications, supported by illustrative clinical cases demonstrating decision-making nuances.

Single operator TAVI: where expertise meets consistency

18 Nov 2025 – From PCR London Valves 2025

This session addresses the concept of single operator transcatheter aortic valve implantation (TAVI), emphasizing the integration of expertise with procedural consistency. Follow a discussion on the benefits of simplifying TAVI to a single operator approach facilitated by an electronically enabled delivery system. The session offers a...

Single operator TAVI: where expertise meets consistency

Complications of LAA closure - Avoidance and management

17 Nov 2025 – From PCR London Valves 2025

Focused on the prevention and management of complications in left atrial appendage (LAA) closure, this session covers recognition of key procedural risks, techniques for safe transseptal puncture, and strategies to prevent and address device embolisation, pericardial effusion, residual leaks, and device-related thrombus, ensuring procedural safety and...

Complications of LAA closure - Avoidance and management

Planning a lifetime of care in younger patients with Evolut FX+: from index valve to future options

17 Nov 2025 – From PCR London Valves 2025

Watch this PCR London Valves 2025 session to take a deep look at the latest evidence in low-risk aortic stenosis, the durability of contemporary valves, and how anatomy — especially in women and patients with small annuli — shapes long-term strategy.

From index TAVI with Evolut FX+...

Planning a lifetime of care in younger patients with Evolut FX+: from index valve to future options

Exceptional engineering, predictable outcomes - Latest development of the VitaFlow TAVI device

17 Nov 2025 – From PCR London Valves 2025

Discover the latest advancements in the VitaFlow transcatheter aortic valve implantation (TAVI) device. This session highlights the electronically enabled VitaFlow Liberty system, delivering consistent immediate and mid-term clinical results. Watch real-world demonstrations of complex cases, including heavily calcified aortas and pure aortic regurgitation, and get a...

Exceptional engineering, predictable outcomes - Latest development of the VitaFlow TAVI device

Prevention and management of TAVI complications

17 Nov 2025 – From PCR London Valves 2025

This session is dedicated to the prevention and management of complications associated with transcatheter aortic valve implantation (TAVI). Participants gain critical knowledge on managing vascular access challenges, anticipating and preventing valve malposition, handling device embolism, and evaluating coronary obstruction risks with effective prevention and bailout strategies.

Prevention and management of TAVI complications

Mitral TEER and LAA closure - LIVE Case

17 Nov 2025 – From PCR London Valves 2025

Watch a LIVE case followed by a recorded case regarding a 91-year-old female with permanent AF, LAD PCI three months earlier, and recurrent GID bleeding who presented with symptomatic severe primary mitral regurgitation due to P2 prolapse and flail. CT imaging showed a LAA with a...

Mitral TEER and LAA closure -  LIVE Case

Align for the future with next gen Myval transcatheter heart valve series

16 Nov 2025 – From PCR London Valves 2025

Discover how the latest Myval transcatheter heart valve (THV) innovations are shaping TAVI outcomes. This PCR London Valves 2025 session highlights the clinical evidence behind the next-gen Myval THV series, best practices for implantation, and upcoming innovations set to improve patient care. Learn step-by-step techniques for deploying Myval...

Align for the future with next gen Myval transcatheter heart valve series

Getting the full potential of the supra-annular valve in a changing landscape

16 Nov 2025 – From PCR London Valves 2025

This session explores the evolving landscape of transcatheter aortic valve implantation (TAVI) with a focus on supra-annular valve technology. It covers techniques for achieving commissural alignment, considerations for small aortic annuli, and advantages in treating bicuspid aortic valve disease, supported by clinical data and illustrative cases.

Getting the full potential of the supra-annular valve in a changing landscape

Redo TAVI with pre and post dilatation - LIVE Case

16 Nov 2025 – From PCR London Valves 2025

Watch this live case followed by a live in a box case, regarding a 93-year-old woman with hypertension, chronic bronchitis, and a history of TAVI with a Sapien 3 23 mm (2016) who presented with symptomatic severe aortic stenosis and mildly reduced LV function (50%). An...

Redo TAVI with pre and post dilatation - LIVE Case

Valve selection in urgent TAVI: evidence from small annulus studies - Hotline

16 Nov 2025 – From PCR London Valves 2025

This session presents cutting-edge research comparing self-expanding and balloon-expandable valves in urgent and emergent TAVI settings, with a focus on small aortic annuli. It includes data from the NAVULTRA and LANDMARK trials, featuring novel biomimetic balloon-expandable valves and early feasibility studies that shed light on valve...

Hotline - TAVI - Part 2

LAAC: current and future indications

03 Jun 2025

Watch the replay of this webinar and learn about the evidence (current guidelines and indications) for LAAC in 2025, and so much more!

Combined LAA closure and transcatheter mitral valve repair - LIVE Case

22 May 2025 – From EuroPCR 2025

An 82-year-old male patient with a history of PM (pacemaker) implantation in 2024, and ischaemic cardiomyopathy presented with symptomatic heart failure due to severe secondary mitral regurgitation and impaired LV function (EF 40 %). He also presented with recurrent gastro-intestinal bleeding while on DOAC for atrial...

Combined LAA closure and transcatheter mitral valve repair - LIVE Case

All you need to know on aorto iliac disease during TAVI: from access to complications management

22 May 2025 – From EuroPCR 2025

Gain expertise in managing aorto-iliac disease during TAVI procedures, from access planning to complication management. This session covers key imaging techniques, decision-making regarding stenting and lesion modification, approaches to access-related complications, and criteria for involving vascular surgeons, ensuring procedural safety and success.

All you need to know on aorto iliac disease during TAVI: from access to complications management

Successful finale - Latest best practices and technologies for large hole arterial and venous closure

22 May 2025 – From EuroPCR 2025

This session covers the latest best practices and technologies for large hole arterial and venous closure, focusing on minimising vascular complications.

Learn about a novel patch-based closure system with encouraging early results in TAVI cases, highlighting the importance of deployment angle and ultrasound guidance.

The venous case presentation...

Successful finale - Latest best practices and technologies for large hole arterial and venous closure