NSTEMI (Non-ST-segment elevation myocardial infarction)

Latest NSTEMI content in interventional cardiology - research, practice, and education

NSTEMI is considered one of the leading causes of morbidity and mortality and its definition and treatment remains challenging requiring specific, adapted responses. Understanding different biomarkers, becoming aware of emerging new agents used in adjunctive pharmacotherapy, keeping abreast of advances in imaging techniques as well as the use of invasive imaging and functional assessment is critical. Tools, devices and techniques, and complications such as different types of vascular access or bleeding risks, can also be found here…

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NSTEMI

241 results

IVORY FINALE study: Low-dose interleukin-2 for the reduction of vascular inflammation in ACS - Clinical outcomes and follow-up

31 Aug 2024

Aaysha Cader interviews Rouchelle Sriranjan about the results of the IVORY and IVORY 2 trials which she presented at the ESC Congress 2024 in London.

The trials examined low-dose interleukin-2 therapy to reduce arterial inflammation in acute coronary syndrome patients. The study found a 7.7% reduction in arterial inflammation...

Author

Aaysha Cader
Rouchelle Sriranjan

Author

Rouchelle Sriranjan

Effect of colchicine on coronary plaque stability in acute coronary syndrome as assessed by optical coherence tomography: the COLOCT randomized clinical trial

27 Aug 2024

The rationale for this study was to provide direct evidence of colchicine's effects on plaque stabilization, particularly by assessing changes in plaque characteristics using optical coherence tomography (OCT).

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti

Reviewer

Salvatore Brugaletta
Effect of colchicine on coronary plaque stability in acute coronary syndrome as assessed by optical coherence tomography: the COLOCT randomized clinical trial

SENIOR-RITA - Older patients with non-ST segment elevation myocardial infarction randomised interventional treatment trial

02 Sep 2024

Mirvat Alasnag provides her take on the SENIOR-RITA trial, presented by Vijay Kunadian at the ESC Congress 2024 in London.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
SENIOR-RITA

Completeness of revascularisation in acute coronary syndrome patients with multivessel disease

28 Jun 2024

Explore evidence on complete revascularisation for patients with STEMI or NSTEMI and multivessel disease, and provide insights into the roles of intracoronary guidance by physiology and imaging.

Completeness of revascularisation in acute coronary syndrome patients with multivessel disease

Durable-polymer versus biodegradable-polymer drug-eluting stents in acute coronary syndromes: three-year outcomes of the HOST REDUCE POLYTECH RCT Trial

20 Jun 2024

This trial found that, in ACS patients undergoing PCI, DP-DES and BP-DES had similar patient-oriented outcomes at three years, but BP-DES had higher device-oriented composite outcomes, mainly due to increased TLR risk.

Nicola Ryan

Reviewer

Nicola Ryan
Durable polymer vs biodegradable polymer DES in ACS 3 year outcomes HOST REDUCE POLYTECH RCT Trial

Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

13 Jun 2024

The results of this study show that IVUS guidance is associated with less late lumen loss compared to angiography guidance in HBR patients undergoing DCB angioplasty.

Nicola Ryan

Reviewer

Nicola Ryan
Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

One- versus three-month dual antiplatelet therapy in high bleeding risk patients undergoing percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes

03 Jun 2024

The optimal duration of short DAPT in ACS patients is unknown, therefore this analysis of the XIENCE Short DAPT programme compared the clinical outcomes of one versus three months DAPT in HBR patients with and without ACS.

Nicola Ryan

Reviewer

Nicola Ryan
One- versus three-month DAPT in HBR patients undergoing PCI for non-ST-segment elevation ACS

Multivessel disease in ACS - which lesions to treat and when

21 May 2024

Watch the replay of this webinar with S. Biscaglia, V. Paradies and P. Smits on how to learn about new evidence for complete revascularisation in ACS and much more!

Multivessel disease in ACS - which lesions to treat and when

PCI of bifurcation lesions: management of complications - Part 3

17 May 2024 – From EuroPCR 2024

This session features additional selected EuroPCR 2024 clinical case submissions focusing on the management of complications during PCI of bifurcation lesions. Cases cover topics such as iatrogenic left main endarterectomy, left main dissections, and unexpected complications during various bifurcation stenting techniques. Discussions emphasize the importance of...

PCI of bifurcation lesions: management of complications - Part 3

Cracking open the discussion on the clinical experience with intravascular lithotripsy in acute coronary syndromes

16 May 2024 – From EuroPCR 2024

Explore this session to uncover the common association between calcium and acute coronary syndrome, and how intravascular lithotripsy (IVL) offers a safe solution for calcified lesions, with comparable procedural success rates. However, note that ACS cases involving calcium may lead to higher major adverse cardiac events...

Cracking open the discussion on the clinical experience with intravascular lithotripsy in acute coronary syndromes

Acute coronary syndromes

16 May 2024 – From EuroPCR 2024

This session, in collaboration with various cardiology societies, focuses on the management of acute coronary syndromes (ACS). It presents three case studies, covering the management of culprit lesions in ACS, tips and tricks in difficult situations, and the management of multivessel disease. The discussions aim to...

Acute coronary syndromes

Challenging scenarios in NSTEMI

16 May 2024 – From EuroPCR 2024

This session features selected clinical case submissions that explore complex and challenging scenarios encountered in the management of NSTEMI patients. Participants will delve into discussions on topics such as coronary artery aneurysm, restenosis of coronary ostial stents, right-sided chest pain, subsequent occlusions of the left anterior...

Challenging scenarios in NSTEMI

Innovative approaches to rare PCI complications in NSTEMI

16 May 2024 – From EuroPCR 2024

This session features selected clinical case submissions that explore complex PCI scenarios in NSTEMI patients. Participants will learn about rare complications following coronary angioplasty, strategies for identifying the correct culprit lesion, techniques for managing pericardial effusion, and other challenging situations encountered during complex PCI in NSTEMI....

Innovative approaches to rare PCI complications in NSTEMI

Optimising the procedural techniques to treat calcified coronary lesions

16 May 2024 – From EuroPCR 2024

This session will provide insights into various techniques and strategies for treating severely calcified coronary lesions. Participants will learn about the use of IVUS guidance, rotational atherectomy, and other plaque modification tools to overcome challenging calcified lesions and achieve optimal stent deployment.

Optimising the procedural techniques to treat calcified coronary lesions

Acute coronary syndromes due to coronary dissection

16 May 2024 – From EuroPCR 2024

This session will explore various cases of acute coronary syndromes caused by coronary dissection. Participants will learn about the diagnosis, management, and treatment strategies for spontaneous coronary artery dissection, including the use of imaging and interventional techniques to address these challenging cases.

Acute coronary syndromes due to coronary dissection

How to solve tricky coronary complications

16 May 2024 – From EuroPCR 2024

From balloon rupture during double-kissing crush stenting to a successful bailout for delayed coronary obstruction post-TAVI, and an unforeseen complication after chimney stenting in a high-risk patient, the session covers it all. Learn about the nuclear mushroom phenomenon during PCI in a calcified LAD, strategies for...

How to solve tricky coronary complications

Acute coronary syndrome caused by coronary aneurysms

16 May 2024 – From EuroPCR 2024

This session will explore various cases of acute coronary syndromes caused by coronary artery aneurysms. Participants will learn about the diagnosis, management, and treatment strategies for these rare and complex cases, including the use of imaging and interventional techniques to address the underlying pathology.

Acute coronary syndrome caused by coronary aneurysms

Stent loss and coronary perforation: how to deal with

16 May 2024 – From EuroPCR 2024

This session explores the management of challenging complications during percutaneous coronary interventions, such as stent loss and coronary perforation. The presenters share case studies that demonstrate various techniques and strategies used to address these complications, including the use of CTO wires for distal wire perforation, managing...

Stent loss and coronary perforation: how to deal with

Challenges in acute coronary syndrome treatment

16 May 2024 – From EuroPCR 2024

This session delves into the challenges and emerging insights in the treatment of acute coronary syndrome (ACS). It features presentations and discussions on topics such as sex-based differences in treatment and outcomes in STEMI, the use of ticagrelor de-escalation strategy in CKD patients, the outcomes of...

Challenges in acute coronary syndrome treatment

Artificial intelligence-powered quantification of coronary physiology and vulnerable plaque: opportunities for novel treatment options

15 May 2024 – From EuroPCR 2024

In this session, uncover new data on Murray-law based quantitative flow ratio (muFR) assessment, providing a comprehensive understanding of PCI outcomes from a single angiographic view, explore the innovative application of artificial intelligence in identifying vulnerable plaque and assessing hemodynamic stenosis significance through the analysis of...

Artificial intelligence-powered quantification of coronary physiology and vulnerable plaque: opportunities for novel treatment options