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Left main and multivessel disease

Find all the latest content on left main and multivessel disease published on this website.

The left main coronary artery provides the primary source of blood flow to the left ventricle. Diseases affecting the left main, by itself or in combination with multivessel disease, place the patient at significant risk for life-threatening cardiovascular events. Treatment requires an understanding of all available tools, devices and techniques, like those employed in invasive imaging and functional assessment, as well as taking into account underlying comorbidities such as diabetes. Advances in imaging techniques, as well as the use of adjunctive pharmacotherapy, vascular access or invasive interventions such as bypass surgery, are important, as are understanding bleeding risks. Use the filters below to access PCRonline resources.

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Left main and multivessel disease

422 results

A case of left main PCI?

17 May 2022 – From EuroPCR 2022

Discover the case of a 74 year-old male presenting with NSTEMI, with an history of lung CA with lobectomy and radiation therapy. The team decided to perform a PCI. How did the procedure go? What challenges did they face and how did they manage them? Watch...

A case of left main PCI?

Treatment of atherosclerotic vasospastic plaque in proximal left anterior descending and left main

17 May 2022 – From EuroPCR 2022

Discover the case of a 57 year-old male patient presenting with chest pain, ECG-ST segment depression in all precordial leads and elevated HS troponins. He already suffered from this event 2 years ago (treated conservatively). Angiogram reveals a vasospastic atherosclerotic plaque in proximal LAD and LM....

Treatment of atherosclerotic vasospastic plaque in proximal left anterior descending and left main

When coronary devices failed

17 May 2022 – From EuroPCR 2022

Discover a selection of cases with coronary devices complications: delayed presentation of left main to LAD stent fracture, PCI in left main stenosis following redo surgical AVR, OCT to shed light on stent failure implanted at the ostium, and much more!

When coronary devices failed

Crash TAVI-in-TAVI complicated by coronary obstruction

20 Apr 2022

Thanks to this Image in Interventional Cardiology, view an emergency TAVI-in-TAVI for cardiogenic shock secondary to acute valve degeneration complicated by left main stem obstruction treated successfully by chimney stenting.

Crash TAVI-in-TAVI complicated by coronary obstruction

Intracoronary imaging and intracoronary physiology: friends or foes?

14 Apr 2022

Watch the replay of this PCR Webinar on Left Main with N. Van Royen, J. Escaned and R. J. Van Geuns

Intracoronary imaging and intracoronary physiology: friends or foes?

COMPLETE: Effects of complete revascularization on angina-related quality of life in patients with ST-segment elevation myocardial infarction

22 Mar 2022

In this interview, Mirvat Alasnag asks Shamir R. Mehta about the results of a prespecified analysis of the COMPLETE study which he presented during the ACC 2022 Scientific sessions. 

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
COMPLETE: effects of complete revascularization on angina-related quality of life in patients with ST-segment elevation myocardial infarction

How to manage a calcified LM bifurcation?

05 Apr 2022

Find out more about an 87-year-old male patient with PCI mid-LAD with BMS 9/1998, several risk factors, preserved LVEF and eGFR, symptomatic with unstable angina, and on medical therapy...

Konstantinos Bermpeis

Author

Konstantinos Bermpeis
Marta Belmonte

Author

Marta Belmonte
Prof. Emanuele BARBATO

Author

Emanuele Barbato
How to manage a calcified LM bifurcation?

Sex differences in outcomes after percutaneous coronary intervention or coronary artery bypass graft for left main disease: from the DELTA registries

07 Mar 2022

The DELTA registry data provides real-world observational evidence that confirms what was reported in randomized trials: a higher rate of co-morbidities in women and better intermediate-term outcomes with CABG. 

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Sex differences in outcomes after percutaneous coronary intervention or coronary artery bypass graft for left main disease: from the DELTA registries

Geographical variations in left main coronary artery revascularisation: a prespecified analysis of the EXCEL trial

14 Feb 2022

The purpose of the prespecified subanalysis of the EXCEL (Evaluation of XIENCE versus Coronary artery bypass surgery for Effectiveness of Left main revascularization) trial was to determine whether the outcomes remained consistent regardless of geography.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag

Reviewer

Ayman Al Saleh
Geographical variations in left main coronary artery revascularisation: a prespecified analysis of the EXCEL trial

One-year outcomes of blinded physiological assessment of residual ischemia after successful PCI - DEFINE PCI trial

10 Feb 2022

The objective of this analysis was to evaluate the impact of residual ischemia detected by post-PCI iFR on clinical outcomes and on residual-angina at the 12-month follow-up of the DEFINE PCI study.

M. Pighi

Reviewer

Michele Pighi
Simone Fezzi

Reviewer

Simone Fezzi
One-year outcomes of blinded physiological assessment of residual ischemia after successful PCI - DEFINE PCI trial