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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Cardiovalve hits the TARGET: advancing transcatheter valve replacement

18 Nov 2025 – From PCR London Valves 2025

This session highlights the features and procedural steps of the next-generation Cardiovalve systems for tricuspid and mitral valve replacement. It reviews interim results from the TARGET study, emphasizing echocardiographic findings and reverse remodeling effects, and discusses best practices for patient selection and the learning pathway to...

Cardiovalve hits the TARGET: advancing transcatheter valve replacement

Transcatheter solutions for failed mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session presents innovative transcatheter solutions for managing failed mitral TEER procedures. It highlights advanced closure strategies for inter-clip mitral regurgitation, percutaneous approaches for recurrent mitral regurgitation, novel chordae tendineae replacement techniques, and potential bailout strategies including atrial flow regulation implantation for recurrent heart failure.

Complex combined transcatheter interventions

18 Nov 2025 – From PCR London Valves 2025

This session addresses complex combined transcatheter interventions for multivalvular heart disease. It covers integrated transcatheter strategies for multiple valve pathologies, solutions for combined severe aortic stenosis and mitral regurgitation with heavy calcification, and approaches to concomitant atrial functional mitral and tricuspid regurgitation. The session also discusses...

Unusual structural interventions - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session highlights unusual structural interventions in cardiology, featuring comprehensive CT screening for left atrial appendage closure, management of procedural complications, novel access techniques for balloon aortic valvuloplasty, transcatheter treatment of mitral bioprosthetic valve vegetation, and percutaneous ventricular septal rupture closure success criteria.

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

Complications of mitral TEER

18 Nov 2025 – From PCR London Valves 2025

This session addresses complications associated with mitral transcatheter edge-to-edge repair (TEER), showcasing innovative bailout methods such as snare-assisted retrieval of undeployed devices, managing leaflet perforations with latest-generation devices, cases of valve-adjacent tears, mechanical support considerations when pumps fail, and the clinical impact of iatrogenic fossa ovalis...

Paravalvular leak closure - Part 4

18 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of paravalvular leak closure with a focus on challenging scenarios including unusual TAVI complications in the mitral position, management of mega paravalvular leaks using jumbo devices, and strategies when closure itself poses an obstacle. It also covers acute peri-operative aortic...

Featured research - Mitral valve interventions - Part 4

18 Nov 2025 – From PCR London Valves 2025

This research-focused session presents contemporary evidence and clinical outcomes related to mitral valve interventions. It includes data on transapical mitral valve-in-ring implantation from the European Tendyne registry, prognostic utility of CT-derived fatty muscle fraction in mitral TEER, and comparative outcomes between transapical TMVR and mitral TEER....

PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global

Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025

17 Nov 2025

View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!

Selection of top Late-breaking Trials presented at #PCRLV