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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Cardiogenic shock: transcatheter solutions

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter solutions for cardiogenic shock, highlighting rescue therapies such as mitral clip intervention in hypertrophic obstructive cardiomyopathy, valve-in-valve TAVI during CPR, and sequential mechanical circulatory support. It presents complex clinical cases illustrating stepwise approaches combining mechanical support and percutaneous valve repair to...

Challenging transcatheter mitral valve replacement

17 Nov 2025 – From PCR London Valves 2025

Explore the complexities of transcatheter mitral valve replacement (TMVR) with discussions on managing mitral annular calcification, preventing paravalvular leaks in mitral valve-in-ring procedures, strategies for larger valve deployment in large mitral rings, and the evolution of transseptal TMVR providing durable relief for previously untreatable cases.

New transcatheter mitral valve devices

17 Nov 2025 – From PCR London Valves 2025

This session reviews emerging transcatheter mitral valve devices and their clinical applications. Topics include managing recurrent mitral regurgitation with combined ELASTA-Clip and TMVR approaches, TMVR use in elderly patients, surgical perspectives on device selection, multimodal percutaneous strategies for functional mitral regurgitation, and TMVR as a novel...

Interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session addresses critical interventions in cardiogenic shock, highlighting innovative approaches such as combined valve procedures, management of acute functional mitral regurgitation in STEMI, and advanced transcatheter edge-to-edge repair techniques in refractory heart failure. It offers a comprehensive exploration of strategies to navigate complex hemodynamic instability...

Transcatheter mitral valve-in-valve - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session addresses transcatheter mitral valve-in-valve and valve-in-ring interventions in complex clinical contexts. It includes cases of rescue procedures in valvular dysfunction, ECMO-assisted mitral valve-in-ring implantation in severe left ventricular dysfunction, and innovative approaches to mitral ring anatomy challenges, offering practical insights and procedural tips for...

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

17 Nov 2025 – From PCR London Valves 2025

This session presents an in-depth examination of the Intrepid transcatheter mitral valve replacement (TMVR) system, focusing on its role in treating mitral regurgitation. It covers the system's design features, ongoing clinical research, and long-term durability, complemented by detailed analyses of transapical 5-year outcomes and current trial...

Shaping the treatment of mitral regurgitation with the Intrepid transcatheter mitral valve replacement (TMVR) system

Mitral interventions in shock

17 Nov 2025 – From PCR London Valves 2025

This session highlights the intricacies of mitral valve interventions in the context of cardiogenic shock. It addresses complex cases including left-to-right shunts post septal puncture, severe ischemic mitral insufficiency with small valve anatomy, emergency mitral TEER for papillary muscle rupture, and bridging strategies to surgery.

Transcatheter mitral valve-in-valve - Part 1

17 Nov 2025 – From PCR London Valves 2025

This session focuses on transcatheter mitral valve-in-valve procedures, emphasizing alternative strategies for optimal alignment and lifetime management planning. It delves into engineering the landing zone for challenging anatomies, the integration of the LAMPOON procedure in TMVR valve-in-valve cases, and addresses complexities arising from mitral annular calcification.

Mastering mitral and tricuspid TEER: clinical strategies in patients with complex anatomy

17 Nov 2025 – From PCR London Valves 2025

Find out more about advanced mitral and tricuspid TEER techniques for patients with challenging anatomy. This PCR London Valves 2025 session highlights real-world approaches from the Asia Pacific region, including consensus recommendations from the Asian Pacific Society of Cardiology, strategies for simultaneous mitral TEER and left...

Mastering mitral and tricuspid TEER: clinical strategies in patients with complex anatomy

TAVI for aortic regurgitation in high surgical risk: outcomes in 700 patients from ALIGN-AR

16 Nov 2025 – From PCR London Valves 2025

Christopher Allen and Raj Makkar sit down to review the ALIGN-AR trial and its implications for treating native aortic regurgitation. 

ALIGN-AR was a pivotal, single-arm, multicenter investigational study designed to evaluate a dedicated transcatheter solution in patients with moderate-to-severe native AR who were considered high risk for...

Outcomes in 700 patients from ALIGN-AR regarding TAVI for AR in high surgical risk