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Mitral valve replacement and repair

Find all the latest content on mitral valve replacement and repair published on this website.

Building on the years of experience with TAVI, mitral valve replacement and repair is now beginning to take-off with a vast array of new techniques and options. Certain devices, for instance in mitral repair, are now widely used. To understand this complex field a knowledge and mastery is required covering the latest research, emerging tools, devices and techniques, vascular access; the role of adjunctive pharmacotherapy; imaging techniques such as echocardiography as well as understanding bleeding risks or patient selection. Find out more…

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Mitral valve replacement and repair

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Mitral valve: PCR London Valves 2025 highlights

17 Nov 2025 – From PCR London Valves 2025

Together with Chris Allen, Course Directors Tiffany Patterson and Nina Wunderlich highlight the Mitral programme from PCR London Valves 2025. The Course began with fundamentals, including imaging and step-by-step procedural training, and then focused on complex cases, complications, and hands-on discussions. LIVE cases featured edge-to-edge repair,...

Mitral valve: PCR London Valves 2025 highlights

Five-year outcomes following early experience with transapical TMVR

16 Nov 2025 – From PCR London Valves 2025

In this discussion, Christopher Allen and Michael Reardon review the five-year results of an early transapical TMVR system implanted in very high-risk, inoperable patients.

The device showed sustained elimination of mitral regurgitation, with over 80% of patients maintaining trace or no MR at five years and no...

Five-year outcomes following early experience with transapical TMVR

ENCIRCLE 1-year outcomes: Shaping the future of MR treatment with the SAPIEN M3 system

18 Nov 2025 – From PCR London Valves 2025

Fabien Praz talks with Mayra Guerrero and Henryk Dreger about the ENCIRCLE trial on the Sapien M3 transcatheter mitral valve, which shows strong safety, durable MR reduction, and improved symptoms, quality of life, and LV remodelling. High-quality CT and echo are essential for #TMVR, which is...

ENCIRCLE 1-year outcomes: Shaping the future of MR treatment with the SAPIEN M3 system

Late-Breaking Trials in transcatheter mitral, tricuspid and aortic interventions - Part 1

16 Nov 2025 – From PCR London Valves 2025

This session presents pivotal late-breaking trials in transcatheter mitral and aortic valve interventions. Explore one-year outcomes from the AltaValve early feasibility study featuring atrial fixation TMVR, interim results from the TARGET study assessing Cardiovalve for tricuspid regurgitation, five-year data on transapical TMVR, and outcomes of TAVI...

The Top Late-Breaking Trials - Part 1

Just CINCH - Indirect annuloplasty for secondary mitral regurgitation in heart failure patients

16 Nov 2025 – From PCR London Valves 2025

This session provides a detailed review of indirect annuloplasty as an interventional treatment for secondary mitral regurgitation in heart failure patients, with a focus on the landmark EMPOWER trial. Learn about patient selection optimisation, procedural considerations involving the coronary sinus and left circumflex artery, and future...

Just CINCH - Indirect annuloplasty for secondary mitral regurgitation in heart failure patients

Featured research: latest advances in mitral TEER and valve repair technologies

16 Nov 2025 – From PCR London Valves 2025

This session presents featured research on mitral valve interventions, including two-year outcomes from the MitraClip G4 EXPAND study, comparative data of mitral TEER versus redo surgery in failed surgical repair, evidence from novel TEER programs in non-surgical centers, and safety and efficacy results of the NeoNova...

Featured research: latest advances in mitral TEER and valve repair technologies

Mitral regurgitation: from guidelines to clinical practice

16 Nov 2025 – From PCR London Valves 2025

This LIVE case symposium brings mitral regurgitation guidelines into real clinical practice. Through step-by-step patient demonstrations and insightful discussion, the session explores how recommendations guide decision-making in ventricular and atrial secondary MR, how the heart team tailors therapy to individual anatomy and comorbidities, and how device iterations...

Mitral regurgitation: from guidelines to clinical practice

Challenging mitral TEER: overcoming access limitations and anatomical challenges

16 Nov 2025 – From PCR London Valves 2025

This session delves into the challenges of mitral transcatheter edge-to-edge repair (TEER), focusing on complex cases such as denied access, patch dehiscence-induced regurgitation, and functional mitral regurgitation due to amyloid cardiomyopathy. It also highlights innovative imaging approaches, including the use of transthoracic echocardiography as a rescue...

Challenging mitral TEER: overcoming access limitations and anatomical challenges

Mitral TEER - LIVE Case

16 Nov 2025 – From PCR London Valves 2025

Watch this live case followed by a recorded case, regarding a 75-year-old male with type 2 DM, permanent AF, and severe LV dysfunction (30%), with a history of RCA PCI one month earlier and three hospitalizations for heart failure, presented with severe secondary mitral and tricuspid...

Mitral TEER - LIVE Case

Hotline - Mitral and tricuspid valvular interventions

16 Nov 2025 – From PCR London Valves 2025

This session delves into innovative mitral and tricuspid valvular interventions, highlighting outcomes with the PASCAL precision system and advances in combined MitraClip and TriClip repairs. It discusses predictors of heart failure hospitalization post-transcatheter tricuspid valve repair (TTVR), coronary CT-based pacemaker implantation prediction, and novel devices aimed...