PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: Bifurcation lesion, Left main and multivessel disease

38 results

Percutaneous coronary intervention versus coronary artery bypass grafting in patients with left main disease with and without diabetes: findings from a pooled analysis of 4 randomized clinical trials

30 Apr 2024

This analysis shows that diabetic patients undergoing revascularization face substantially higher 5-year rates of all-cause mortality, myocardial infarction, repeat revascularizations, and stroke compared to non-diabetic patients.

Alessandro Sticchi

Reviewer

Alessandro Sticchi
Prof. Antonio Colombo

Reviewer

Antonio Colombo
PCI vs CABG in patients with LM disease with and without diabetes: findings from a pooled analysis of 4 randomized clinical trials

Bifurcation left main stenting with or without intracoronary imaging: Outcomes from the EBC MAIN trial

08 Aug 2023

This sub-analysis of EBC MAIN aimed to determine if intracoronary imaging use during LM bifurcation PCI was associated with fewer MACE, for patients treated with a planned dual‐stenting strategy versus provisional strategy.

Reviewer

Aaysha Cader
Saidur Rahman Khan

Reviewer

Saidur Rahman Khan
Bifurcation left main stenting with or without intracoronary imaging: Outcomes from the EBC MAIN trial

Percutaneous coronary intervention vs coronary artery bypass graft surgery for left main disease in patients with and without acute coronary syndromes: a pooled analysis of 4 randomized clinical trials

05 Jul 2023

This patient-level analysis of randomized trials comparing PCI vs CABG for the treatment of low-to-intermediate CAD involving the LM confirms the absence of long-term differences in mortality between revascularization techniques, regardless of the clinical presentation.

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti
Daniele Giacoppo

Reviewer

Daniele Giacoppo
PCI vs CABG surgery for LM disease in patients with and without ACS: a pooled analysis of 4 randomized clinical trials

PCI or CABG for left main coronary artery disease: the SWEDEHEART registry

28 Jun 2023

While the choice between PCI and CABG for LMCA disease continues to be one of the most controversial topics, patient characteristics & comorbidities must be taken into account, as must the external validity of the results of RCTs in the real world, as the SWEDEHEART registry does.

Panagiotis Xaplanteris

Reviewer

Panagiotis Xaplanteris

Reviewer

Leonidas Koliastasis
PCI or CABG for left main coronary artery disease: the SWEDEHEART registry

Stepwise provisional versus systematic culotte for stenting of true coronary bifurcation lesions: five-year follow-up of the multicentre randomised EBC TWO Trial

16 Jun 2023

The investigator initiated, multicentre, randomised, EBC TWO trial compared a provisional strategy with a systematic culotte technique in patients with true non-LMS bifurcation disease. At one year, there was no difference between the groups in terms of the composite endpoint of all-cause mortality, MI or TVR....

Nicola Ryan

Reviewer

Nicola Ryan
Stepwise provisional versus systematic culotte for stenting of true coronary bifurcation lesions: five-year follow-up of the multicentre randomised EBC TWO Trial

The 17th expert consensus document of the European Bifurcation Club – techniques to preserve access to the side branch during stepwise provisional stenting

15 Jun 2023

Provisional stenting (PS) is the default approach for treating most coronary bifurcation lesions (CBL). The side branch (SB) can be compromised after main vessel (MV) stenting in up to 6-18 % of cases. The 17th Expert consensus document of the European Bifurcation Club details strategies for...

Reviewer

Aaysha Cader
Ali Nazmi Calik

Reviewer

Ali Nazmi Calik
The 17th expert consensus document of the European Bifurcation Club – techniques to preserve access to the side branch during stepwise provisional stenting

Outcomes of medical therapy plus PCI for multivessel or left main CAD ineligible for surgery

09 Mar 2023

The OPTIMUM study evaluates the outcomes in patients with complex CAD, including significant LM disease, its equivalent, or MVD CAD, undergoing percutaneous revascularization in addition to guideline directed medical therapy (GDMT) versus GDMT alone.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag

Reviewer

Pooja M. Swamy
Outcomes of medical therapy plus PCI for MVD or LM CAD ineligible for surgery

Left main stem percutaneous coronary intervention: does on-site surgical cover make a difference?

28 Oct 2022

The current analysis examines patient characteristics and outcomes following LM PCI performed in NSC in England and Wales.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Turki B Albacker

Reviewer

Turki B Albacker
Left main stem percutaneous coronary intervention: does on-site surgical cover make a difference?

A large, prospective, multicentre study of left main PCI using a latest-generation zotarolimus-eluting stent: the ROLEX study

24 Oct 2022

The purpose of the ROLEX Registry (Revascularization Of LEft main with resolute onyX) was to explore outcomes using a more contemporary drug eluting stent platform which is more suitable for LM PCI.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
A large, prospective, multicentre study of left main PCI using a latest-generation zotarolimus-eluting stent: the ROLEX study

Durable polymer vs. biodegradable polymer DES in patients with ACS undergoing complex PCI: A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial

30 Aug 2022

The HOST-REDUCE-POLYTECH-ACS trial was a randomised, parallel-group multicentre trial with a 2x2 factorial design testing two independent hypotheses, one of which was the non-inferiority of durable polymer drug-eluting stents (DP-DES) to biodegradable polymer drug-eluting stents (BP-DES) in patients with ACS. In this post-hoc analysis, the authors...

Nicola Ryan

Reviewer

Nicola Ryan
A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial