PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: Stents, scaffolds and DCB

26 results

Bioresorbable vascular scaffold versus metallic drug-eluting stent in patients at high risk of restenosis: final 7-year results of the COMPARE-ABSORB trial

10 Mar 2026

This study provides the longest available follow-up for first-generation bioresorbable vascular scaffolds and fails to demonstrate any late clinical advantage after complete scaffold resorption.

Emanuele Gallinoro

Reviewer

Emanuele Gallinoro
Bioresorbable vascular scaffold versus metallic drug-eluting stent in patients at high risk of restenosis: final 7-year results of the COMPARE-ABSORB trial

Drug-coated balloon angioplasty vs up-front stenting for de novo CAD: 3-year follow-up of REC-CAGEFREE I trial

10 Mar 2026

The 3-year follow-up of the REC-CAGEFREE I trial demonstrated that a DCB-based strategy with rescue stenting was associated with a significantly higher rate of DOCE compared with contemporary DES implantation in patients with de novo, non-complex coronary artery disease.

Reviewer

Ali Nazmi Calik
Murat Gökalp

Reviewer

Murat Gökalp
Drug-coated balloon angioplasty vs up-front stenting for de novo CAD: 3-year follow-up of REC-CAGEFREE I trial

Validation of intravascular ultrasound-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

17 Nov 2025

This individual patient data analysis of the three largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated with reduced TVF at one year. 

Ruxandra Sava

Reviewer

Ruxandra Sava
Nicola Ryan

Reviewer

Nicola Ryan
Validation of IVUS-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial

31 Mar 2025

Which ballooning technique is best after main vessel stenting in bifurcation PCI? This two-part study compares two key approaches: PKP (POT, kissing balloon inflation, final POT) and PSP (POT, isolated side branch dilation, final POT) to determine the optimal strategy.

Reviewer

Ali Nazmi Calik

Reviewer

Aaysha Cader
Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial

Percutaneous coronary treatment with Bioadaptor implant vs drug-eluting stent : 2-year outcomes from BIOADAPTOR RCT

31 Mar 2025

At two-year follow-up, the use of sirolimus-eluting cobalt-chromium DynamX Drug Eluting Coronary Bioadaptor System (Elixir Medical Corporation) resulted in fewer target lesion failure (TLF) compared with the Resolute Onyx contemporary drug-eluting stent.

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti

Reviewer

Salvatore Brugaletta
Percutaneous coronary treatment with Bioadaptor implant vs drug-eluting stent : 2-year outcomes from BIOADAPTOR RCT

Rotational atherectomy, lithotripsy, or laser for calcified coronary stenosis: the ROLLER COASTR-EPIC22 trial

24 Mar 2025

Due to a lack of randomised evidence, this randomised controlled trial (RCT) aimed to compare the safety and efficacy of IVL and ELCA with RA in treating heavily calcified coronary lesions before drug-eluting stent implantation.

Reviewer

Ali Nazmi Calik

Reviewer

Aaysha Cader
Rotational atherectomy, lithotripsy, or laser for calcified coronary stenosis: the ROLLER COASTR-EPIC22 trial

A randomised trial of sirolimus- versus paclitaxel-coated balloons for de novo coronary lesions

05 Dec 2024

The present study compares a novel sirolimus-coated balloon with a clinically proven paclitaxel-coated balloon for the treatment of de novo coronary lesions, demonstrating non-inferiority in terms of angiographic late lumen loss at 6 months.

Mauro Gitto

Reviewer

Mauro Gitto
Nicola Ryan

Reviewer

Nicola Ryan
A randomised trial of sirolimus- versus paclitaxel-coated balloons for de novo coronary lesions

Optical coherence tomography predictors of clinical outcomes after stent implantation: the ILUMIEN IV trial

04 Nov 2024

The aim of this pre-specified analysis of the ILUMIEN IV trial was to assess the relationship between post-PCI OCT parameters of suboptimal stent implantation and clinical outcomes.

Rick Volleberg

Reviewer

Rick Volleberg
Nicola Ryan

Reviewer

Nicola Ryan
Optical coherence tomography predictors of clinical outcomes after stent implantation: the ILUMIEN IV trial

Durable-polymer versus biodegradable-polymer drug-eluting stents in acute coronary syndromes: three-year outcomes of the HOST REDUCE POLYTECH RCT Trial

20 Jun 2024

This trial found that, in ACS patients undergoing PCI, DP-DES and BP-DES had similar patient-oriented outcomes at three years, but BP-DES had higher device-oriented composite outcomes, mainly due to increased TLR risk.

Nicola Ryan

Reviewer

Nicola Ryan
Durable polymer vs biodegradable polymer DES in ACS 3 year outcomes HOST REDUCE POLYTECH RCT Trial

Quantitative coronary angiography vs intravascular ultrasonography to guide drug-eluting stent implantation - a randomized clinical trial

21 Mar 2024

The trial aimed to establish the non-inferiority of QCA-guided PCI compared to IVUS-guided PCI with respect to the primary endpoint of TLF at 12 months, defined as a composite of cardiac death, target vessel MI, or ischemia-driven target lesion revascularization.

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti

Reviewer

Salvatore Brugaletta
QCA vs IVUS to guide DES implantation - a randomized clinical trial