
Chiara De Biase
Latest contributions
From the legs to the coronaries: How Andreas Grüntzig reached his dream
In this final episode, Chiara De Biase and Jean Marco trace the journey of transluminal angioplasty from Charles Dotter in the US to Andreas Grüntzig in Europe. Grüntzig's vision was to apply balloon angioplasty to treat coronary artery stenosis, for which he defined clear goals and working axes....

The AQUATIC trial: Assessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation
01 Sep 2025
Chiara De Biase provides her take on the results of AQUATIC presented by Martine Gilard at ESC Congress 2025 in Madrid.

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PCRonline @ ESC Congress 2025: the interventional cardiology perspective!
26 Jul 2025
Stay updated with the latest in interventional cardiology at #ESCCongress 2025!

TAVI in bicuspid: all you need to know
22 May 2025 – From EuroPCR 2025
Understand the unique anatomical and clinical challenges of transcatheter aortic valve implantation (TAVI) in bicuspid aortic valves. This session covers bicuspid valve epidemiology, indications for surgery and TAVI, and detailed discussion on sizing and deployment fundamentals specific to bicuspid anatomy to optimize procedural success.

Streamlining the TAVI pathway
21 May 2025 – From EuroPCR 2025
Optimize your TAVI pathway through this session focusing on streamlined pre-procedural planning, minimalist procedural techniques, and post-procedural discharge strategies. Learn how to safely deliver multiple cases per list and implement next-day or same-day discharge programs effectively.

How to handle the most clinically relevant challenges in TAVI
21 May 2025 – From EuroPCR 2025
This session explores some of the most clinically complex scenarios encountered in TAVI practice. Three real-world cases address key challenges such as intervention sequencing and transcatheter valve selection in patients with combined coronary artery disease and severe aortic stenosis. The session also examines coronary obstruction risk assessment and...

How to manage the challenges of TAVI in bicuspid disease?
22 May 2025 – From EuroPCR 2025
How should TAVI be adapted to the unique challenges of bicuspid aortic valve disease? In this EuroPCR 2025 discussion, Chiara De Biase, Kentaro Hayashida, and Didier Tchetche explore the key anatomical and procedural considerations for tailoring treatment. From selecting which bicuspid anatomies are suitable for TAVI...

Dapagliflozin in patients undergoing transcatheter aortic valve implantation (DapaTAVI)
10 Apr 2025
Chiara De Biase interviews Sergio Raposeiras-Roubin about the results of the DapaTAVI trial which he presented during the ACC.25 in Chicago.

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Voices from the past – 60 years of transluminal angioplasty in podcast format
06 Feb 2025
Dive into six decades of innovation in transluminal angioplasty! Hosted by Jean Marco and Chiara De Biase, each episode features in-depth conversations with these visionary figures, offering historical perspectives and inspiring messages to shape the future of clinical practice. ...

PCRonline @ ACC.25 Scientific Sessions
07 Feb 2025
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2025 Scientific Sessions #ACC25

Best of science and education in cardiovascular interventional medicine in 2024
16 Dec 2024
Dear Colleagues, dear PCR Companions,
As we welcome a new year, it is the perfect time to reflect on what we achieved together over the past year—both as a celebration of our successes and as motivation to continue improving in the year ahead.
2024 was a record year...

TRISCEND II: Top Late Breaking Trial at PCR London Valves 2024
26 Nov 2024 – From PCR London Valves 2024
Chiara De Biase and Raj Makkar share key insights from the TRISCEND II study. This innovative research addresses a crucial question: can transcatheter tricuspid valve replacement improve symptoms, quality of life, and clinical outcomes in patients? Listen as Makkar details the enrolled population and the study's...

Compare TAVI - Top Late Breaking Trial at PCR London Valves 2024
26 Nov 2024 – From PCR London Valves 2024
Chiara De Biase and Christian Terkelsen review the one-year results of the Compare TAVI randomized study, which set a benchmark for evaluating the performance and safety of new transcatheter heart valves (THVs) compared to best-in-practice THVs. The findings revealed that the Myval THV series was non-inferior...

Mitral valve: PCR London Valves 2024 highlights
26 Nov 2024 – From PCR London Valves 2024
Chiara De Biase interviews Sam Dawkins and Francesco Maisano about the PCR London Valves 2024 highlights on mitral valve disease. They highlight sessions analyzing the latest trial evidence, including the two-year data from the MiCLASP and CLASP IID studies. The Congress also stands out for its...

TAVI - Advanced skills: overcoming challenges in transfemoral procedures
24 Nov 2024 – From PCR London Valves 2024
Discover how to master advanced techniques and navigate the most challenging situations in transfemoral TAVI procedures. This session will guide you through the potential pitfalls, teach you how to manage unanticipated scenarios and provide strategies for addressing complications during transcatheter heart valve (THV) deployment.
You’ll also dive...

TAVI and coronary artery disease
24 Nov 2024 – From PCR London Valves 2024
How does coronary artery disease shape outcomes in TAVI patients, and when should revascularization come into play? This video explores these critical questions, offering a deep dive into the latest evidence and strategies for managing combined aortic stenosis and coronary artery disease.
From understanding revascularization timing to...

How to deal with ilio-femoral tortuosity during TAVI procedure: the buddy wire technique to straighten the pathway
09 Sep 2024

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RHEIA - Transcatheter versus surgical aortic valve replacement in women with severe aortic stenosis
01 Sep 2024
While Chiara De Biase interviews Helene Eltchaninoff about the RHEIA trial results, which she presented at the ESC Congress 2024 in London, Panos Xaplanteris shares his perspective on the trial, offering all the essential information and key takeaways you need for your practice!

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NOTION-3 - Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation
01 Sep 2024
Make the most of the insights from Jacob Thomsen Loenborg’s interview with Chiara De Biase and Ali Nazmi Calik’s article to capture the key takeaways from this trial, simultaneously published in the NEJM, presented at the ESC Congress 2024 in London.

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PCRonline @ ESC Congress 2024: the interventional cardiology perspective!
26 Jul 2024
What was new and hot in interventional cardiology at #ESCCongress 2024!

Focus on EAPCI PCR Fellows Course
18 Jun 2024 – From EuroPCR 2024
In celebration of the tenth anniversary of the EAPCI PCR Fellows Course, Gabor Toth interviews Chiara De Biase about the initial target participants of the Course, the topics covered during this one-day event, and the decision to exclude structural topics to promote the PCR London Valves...

Bicuspid disease - All you need to know
16 May 2024 – From EuroPCR 2024
This session is ideal if you want to understand the anatomical features of bicuspid aortic stenosis, learn about the latest post-TAVI clinical outcomes in bicuspid aortic valves, grasp key considerations for TAVI sizing in these cases, and analyze both self-expanding and balloon-expandable TAVI procedures in bicuspid...

Contemporary TAVI: the VISION of lifetime management
15 May 2024 – From EuroPCR 2024
In this session, discover how pre-procedural assessment is used to optimize procedural outcomes, ensuring the best possible results for patients undergoing TAVI, learn the intricacies of selecting the most suitable valve for each individual patient, considering their unique anatomical and clinical factors, and engage in discussions...

How did Dotter's method make its way to Europe and result in Andreas Grüntzig’s balloon catheter?
In this episode, Chiara De Biase and Jean Marco discuss how Eberhard Zeitler, inspired by Dotter's work, introduced the method in Germany. Grüntzig, known for his solid medical background and empathetic demeanor, received crucial support from colleagues. His determination, teamwork, and commitment led to the development of a flexible...

Transluminal angioplasty: Why was Dotter's disruptive innovation initially rejected?
In this interview, Chiara De Biase and Jean Marco embark on a journey through the history of interventional medicine, focusing on Charles Dotter, the pioneer of transluminal angioplasty, and Andreas Grüntzig.
In this second episode, they highlight three key reasons for Charles Dotter's failure to spread his method widely in the...

A journey with Charles Dotter: his contribution to transluminal angioplasty
In this interview, Chiara De Biase and Jean Marco embark on a journey through the history of interventional medicine, focusing on Charles Dotter, the pioneer of transluminal angioplasty, and Andreas Grüntzig.
In this first episode, they discuss Dotter's groundbreaking contributions, including the first interventional transluminal angioplasty in 1964, which revolutionized...

60 years of transluminal angioplasty: The epic tale of two pioneers, Dotter & Grüntzig
22 Feb 2024
on 16 September 1977, Andreas Gruntzig made history and changed the face of cardiology forever. Jean Marco and Chiara De Biase embark on a journey through the history of interventional cardiology...

Focus on the imaging learning center
22 Nov 2023 – From PCR London Valves 2023
Chiara De Biase and Nicolo Piazza explore the rationale behind the Imaging Learning Center, established in response to a real need for comprehensive learning in cardiovascular imaging throughout pre-, intra-, and post-procedural phases. Within this dedicated imaging space, various concepts are discussed, spanning from the aortic...

TAVI in complex scenarios - Bicuspid aortic valve disease - putting it all together
20 Nov 2023 – From PCR London Valves 2023
After an overview of what is currently known about TAVI in bicuspid aortic valves, follow the analysis of a real-life clinical case, and get tips on how to perform TAVI in a bicuspid aortic valve in 3 different ways: with a self-expanding supra-annular valve, using a...

Complex tricuspid interventions
20 Nov 2023 – From PCR London Valves 2023
Consult this session to discover a selection of abstracts regarding tricuspid valve procedures: explore the complexities of long-term right heart remodeling after transcatheter tricuspid annuloplasty, witness the journey from pre-clinical studies to the first-in-man experience with MonarQ tricuspid valve replacement, delve into Tripair, an innovative transcatheter spacer...
