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Complications of paravalvular leak closure

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complexities and risks associated with paravalvular leak (PVL) closure. It offers detailed analysis of principal complications, prevention techniques, and practical management strategies shared by experienced operators. Case studies illustrate complications such as device embolisation, prosthetic valve disc impingement, and delivery failures, along...

TAVI complications - Part 2

17 Nov 2025 – From PCR London Valves 2025

This session explores complex and uncommon complications associated with TAVI procedures, highlighting challenging clinical scenarios such as neurological complications in bicuspid valves, management of critically unstable left ventricles, and outcomes in complex valve interventions. Each topic offers valuable lessons for improving procedural safety and patient outcomes...

Getting to the heart of access: mastering femoral puncture and vascular closure

18 Nov 2025 – From PCR London Valves 2025

This session provides an in-depth understanding of femoral anatomy and the critical role of imaging in ensuring safe vascular access via femoral puncture. It covers the latest equipment used for vascular access and closure, highlighting haemostasis techniques and closure devices. Interactive case scenarios offer practical insights...

Thrombotic complications of transcatheter valves

17 Nov 2025 – From PCR London Valves 2025

Focusing on thrombotic complications following transcatheter valve implantation, this session presents a series of complex cases illustrating acute and late thrombotic events, their clinical presentations, and the pivotal role of multimodality imaging in diagnosis and management. Insights include coronary embolism and cardiogenic shock scenarios, emphasizing challenges...

TAVI embolisation - Part 1

18 Nov 2025 – From PCR London Valves 2025

This session explores the critical issue of TAVI valve embolisation, presenting real-world cases that emphasize rapid problem-solving and interventional management strategies. Discussions include bailout techniques for embolised valves, managing multiple valve implantations in severe aortic stenosis, and expectations for TAVI in pure aortic regurgitation. The session...

Multiple valve interventions

17 Nov 2025 – From PCR London Valves 2025

This session delves into the complexities of multiple valve interventions, showcasing a fully transcatheter strategy for combined complex heart procedures. It presents stepwise approaches for managing multivalvular disease with severe pulmonary hypertension and sequential transcatheter strategies when single valve treatment is insufficient. Additional focus is given...

Transcatheter tricuspid valve replacement - LIVE Case

18 Nov 2025 – From PCR London Valves 2025

Live case: An 86-year-old male, with a history of PPM, permanent AF, CKD stage 3, and moderately impaired LV function (50–55%), presented with symptomatic torrential mixed TR (tricuspid annular dilatation and pacing lead on the septal leaflet). An Evoque valve was implanted under fluoroscopy and TEE...

Transcatheter tricuspid valve replacement - LIVE Case

Featured research: imaging innovation and device performance in TAVI

18 Nov 2025 – From PCR London Valves 2025

This session presents featured research on TAVI, highlighting long-term outcomes and innovations in transcatheter aortic valve therapy. It includes registry data on mild paravalvular leak impact, five-year evaluations of the Hydra THV, comparisons between deep learning and manual echocardiographic assessments, pacemaker implantation outcomes post-TAVI, and procedural...

Featured research: imaging innovation and device performance in TAVI

Complications of valve-in-valve TAVI

18 Nov 2025 – From PCR London Valves 2025

This session addresses the complex complications associated with valve-in-valve TAVI procedures. Topics include delayed coronary compromise, unexpected clinical scenarios, the importance of recognizing surgical bioprosthesis types, the dual role of calcium in TAVI, and intricate left ventricular complications that can arise post valve-in-valve interventions.

Challenging mitral interventions

18 Nov 2025 – From PCR London Valves 2025

This session explores the complexities of mitral interventions, highlighting advancements and challenges in transcatheter mitral valve repair (TMVR). Topics include the benefits of a simplified single-step TMVR approach, the influence of hemodynamic parameters on MitraClip therapy outcomes, strategies for managing persistent pulmonary oedema, and approaches to...

TAVI: alternative access - Part 2

18 Nov 2025 – From PCR London Valves 2025

This session addresses alternative access routes for TAVI in patients with challenging vascular anatomy. Topics include transapical valve-in-valve procedures complicated by severe aortic regurgitation, percutaneous TAVI via the brachiocephalic trunk, and strategies for managing hostile vascular anatomies. Solutions for scenarios where transfemoral TAVI is not feasible...

Transcatheter management of failed THV - LIVE case

09 Feb 2025 – From PCR Tokyo Valves 2025

An 84-year-old woman with diabetes mellitus, frailty (5/6), preserved LV function, and aortic stenosis previously treated with CoreValve 26 mm in 2016, presented with symptomatic degenerative stenosis of the valve.
A Sapien 3 (23 mm) was implanted without predilatation but with post-dilatation under general anaesthesia, using cerebral...

Transcatheter management of failed THV - LIVE case

COVID-19: Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

07 Jan 2021

Examination of the study methodology and results according to the PICOT principle, SWOT analysis and real-world applicability

COVID-19: Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

The CLEAR SYNERGY (OASIS 9) Trial: A 2x2 factorial randomized controlled trial of colchicine versus placebo and spironolactone versus placebo in patients with myocardial infarction

18 Nov 2024

Mirvat Alasnag provides her take on the CLEAR SYNERGY trial presented by Sanjit S Jolly at AHA 2024 in Chicago.

Dr. Mirvat Alasnag

Author

Mirvat Alasnag
CLEAR SYNERGY

Top Interventional Trials presented at ACC.21

07 Jun 2021

Ali Nazmi Calik provides a summary and key take-aways and infographics of 9 major trials of interest to interventional cardiologists presented at ACC.21

Author

Ali Nazmi Calik
Top Interventional Trials presented at ACC.21
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