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Impact of pullback pressure gradient on clinical outcomes after percutaneous coronary interventions

02 Dec 2025

While FFR traditionally reflects the severity of a lesion at a fixed location, PPG incorporates the pullback profile, enabling a more comprehensive understanding of disease distribution.

Emanuele Gallinoro

Reviewer

Emanuele Gallinoro
Nicola Ryan

Reviewer

Nicola Ryan
Impact of PPG on clinical outcomes after PCI

When the first TAVI fails: no panic, just planning

02 Dec 2025

An 81-year-old man with history of severe aortic stenosis previously treated with a balloon-expandable transcatheter valve was referred for progressive exertional dyspnea due to bioprosthetic valve degeneration.

How would you treat this patient?

Barbara Bellini

Author

Barbara Bellini
When the first TAVI fails: no panic, just planning

1-year SELUTION DeNovo results: drug-eluting balloon strategy vs. systematic drug-eluting stent in de novo coronary disease

29 Oct 2025

Guillaume Bonnet interviews Christian Spaulding about the SELUTION DeNovo Trial he presented at TCT 2025, in San Francisco. 

Prof. Christian Spaulding, principal investigator of the study, discusses the trial design, key outcomes, breaks down the nuances behind the sirolimus DCB strategy versus contemporary DES, and shares insights...

Guillaume Bonnet

Author

Guillaume BONNET

Author

Christian Spaulding
1-year SELUTION DeNovo results: DEB strategy vs. systematic DES in de novo coronary disease

PCR London Valves 2025: Best of Social Media Coverage

20 Nov 2025

This year’s coverage was built on innovative formats to support one clear strategy: sharing strong messages and high-quality education through well-prepared, creative content. The #PCRLV social media team was led by Pamela Gatto, and divided into 6 tracks: aortic, mitral, tricuspid, closure, imaging and nursing.

PCR London Valves 2025: Best of Social Media Coverage

PCR: Collaborative, inclusive and global

15 Nov 2025 – From PCR London Valves 2025

At PCR, collaboration and inclusion are at the heart of everything we do.

Together, we create an environment where expertise is shared, talents complement each other, and diversity becomes a strength. It is this collective spirit that drives interventional cardiology forward and inspires innovation every day.

During PCR London...

PCR: Collaborative, inclusive and global

Validation of intravascular ultrasound-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

17 Nov 2025

This individual patient data analysis of the three largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated with reduced TVF at one year. 

Ruxandra Sava

Reviewer

Ruxandra Sava
Nicola Ryan

Reviewer

Nicola Ryan
Validation of IVUS-defined optimal stent expansion criteria for favorable 1-year clinical outcomes

Spotlight on a selection of top Late-breaking Trials presented at PCR London Valves 2025

17 Nov 2025

View a snapshot of the results of these 4 trials in valvular and structural interventions presented in London during this year's Heart Team Course!

Selection of top Late-breaking Trials presented at #PCRLV

PARTNER 3: transcatheter or surgical aortic-valve replacement in low-risk patients at 7 years

14 Nov 2025

At 7 years, low-risk patients affected by severe symptomatic aortic valve stenosis 1:1 randomly treated by SAPIEN 3 TAVI or surgery showed similar clinical outcomes and late valve durability

Igor Belluschi

Reviewer

Igor Belluschi

Reviewer

Salvatore Brugaletta
PARTNER 3: TAVR or SAVR in low-risk patients at 7 years

Ten trials from AHA 2025

12 Nov 2025

Alessandro Sticchi provides us with a curated overview of the late-breaking trials he found most relevant for interventional cardiologists from AHA 2025.

Alessandro Sticchi

Author

Alessandro Sticchi
Ten trials from AHA 2025

MITRACURE: From results to next steps

Edoardo Zancanaro interviews Julien Dreyfus & David Messika-Zeitoun about the MITRACURE registry, a large international initiative aimed at capturing real-world data on patients with mitral regurgitation referred for surgery. in 2019. The study shows outcomes differ from expert centers, with higher mortality and lower repair rates, especially...

MITRACURE: From results to next steps