ENTRUST-AF PCI - Edoxaban-based versus vitamin-K-antagonist-based antithrombotic regimen following successful coronary stenting in atrial fibrillation patients

Reported from the European Society of Cardiology ESC Congress 2019 in Paris

Francesco Costa, Italy, interviews Pascal Vranckx, PI of the ENTRUST-AF-PCI Trial

  • Question 1: How do you explain the difference in results between ENTRUST-AF-PCI and prior trials?
  • Question 2: How would you explain the differences between the two meta-analyses presented during the session on Antithrombotic therapy in atrial fibrillation patients undergoing PCI?
  • Question 3: Is a signal towards an excess of stent thrombosis with Aspirin withdrawal observed in several trials a statistical streak or is it a real clinical issue?