PCR Journal Club

The HOST-REDUCE-POLYTECH-ACS trial was a randomised, parallel-group multicentre trial with a 2x2 factorial design testing two independent hypotheses, one of which was the non-inferiority of durable polymer drug-eluting stents (DP-DES) to biodegradable polymer drug-eluting stents (BP-DES) in patients with ACS. In this post-hoc analysis, the authors...

This sub-analysis of ISCHEMIA has shown that implementation of a simple protocol of optimal medical therapy is a key factor to improve health outcome and practical in real-world settings.

In this post-hoc analysis of the TWILIGHT trial, the authors report the effects of ticagrelor monotherapy compared to ticagrelor and aspirin in patients with prior CABG at least three months post PCI with no adverse events and at least one clinical and one angiographic high-risk feature...

The primary objective of the study was to assess whether an IVUS-based stent optimization provided an incremental value in terms of vessel-related adverse event occurrence in patients presenting with low post-PCI FFR (<0.90).

Wollmuth et al in the RESTORE EF study sought to examine the impact of Impella assisted HRPCI on LV function at 90-day follow-up.

The STRENGTH study is a multicentre prospective randomised trial investigating whether RenalGuard is superior to standard intravenous hydration in preventing contrast induced nephropathy in patients with chronic kidney disease (CKD) undergoing complex cardiovascular procedures.

The ST-OHCA study is a single centre prospective study investigating the incidence, timing and predictors of definite stent thrombosis in comatose survivors of out-of-hospital cardiac arrest (OHCA) undergoing immediate PCI and therapeutic hypothermia.

Part I of the 16th EBC consensus document presents a detailed analysis of possible pitfalls associated with each step of the provisional single stent approach and it provides a compendium of the pertinent strategies for rescue and prevention. Also included in this review: lead author Remo Albiero...

Although the default strategy remains a stepwise provisional strategy, the authors of the 16th expert consensus document recognize that up to 25 % of all single stent approaches eventually require a second.