PCR Journal Club

The present systematic review and meta-analysis by Ferrante et al aimed to provide a comprehensive quantitative analysis of the effects of DRA vs TRA, by pooling data from randomised controlled trials (RCT) comparing these two access sites when used for coronary angiography and/or percutaneous coronary intervention...

FAVOR-III China was an investigator-initiated, multicentre, randomised, blinded, sham-controlled trial comparing clinical outcomes of QFR versus angiography-guided strategies for the treatment of non-critical lesions in patients with stable or unstable angina, or MI, at least 72 hours prior to screening. The one-year results showed improved clinical...

The HOST-EXAM trial1 was a prospective, randomised, open-label trial investigating clopidogrel monotherapy versus aspirin therapy in patients undergoing PCI with DES who had completed 6-18 months of DAPT with no ischaemic or bleeding complications. At 24 months follow-up, clopidogrel monotherapy significantly reduced the risk of the...

The current analysis examines patient characteristics and outcomes following LM PCI performed in NSC in England and Wales.

Edoardo provides us with the cardiac surgeon's point of view!

The present trial aimed to clarify the hemodynamic results between balloon-expandable valve (BEV) (SAPIEN 3 ULTRA - Edwards) and self-expandable valve (SEV) (EVOLUT R/Pro/Pro+ - Medtronic) in case of dysfunctional small-sized surgical bio-prosthesis.

The purpose of the ROLEX Registry (Revascularization Of LEft main with resolute onyX) was to explore outcomes using a more contemporary drug eluting stent platform which is more suitable for LM PCI.

The new analysis from the COAPT trial indicated that lower secondary mitral regurgitation by TEER was strongly associated with reduced heart failure hospitalization, all-cause mortality, and improved quality of life as compared with a higher degree of residual MR.

Optical Coherence Tomography fractional flow reserve (OCT-FFR) has been shown to correlate well with wire-based FFR; however, clinical outcomes based on OCT-FFR are not well defined. In this retrospective study, the authors sought to investigate the relationship between OCT-FFR and long-term clinical outcomes in ACS. 

Although tricuspid regurgitation has for a long time been “the forgotten valve”, recently there has been a rising awareness of the disease with several important studies investigating its pathophysiology and treatment.