PCR Journal Club

In patients with multivessel disease who were event-free 12 months after drug-eluting stent implantation, a further 12 months of clopidogrel plus aspirin reduced ischaemic events compared with aspirin monotherapy, with no detectable excess of adjudicated bleeding.

In patients with non-left main coronary bifurcation lesions treated with provisional stenting and POT, the KISS randomised trial compares a strategy of no side branch intervention versus systematic side branch treatment.

Long-term evidence comparing PCI and CABG for unprotected left main coronary disease has been limited and sometimes conflicting. The 10-year results from the NOBLE trial now provide important clarity on all-cause mortality outcomes with both revascularisation strategies.

This study represents a prespecified subgroup analysis of the COMPLETE randomised trial, a large, international, randomised controlled study comparing a strategy of complete revascularisation with culprit-only percutaneous coronary intervention (PCI) in patients presenting with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD).

The present...

This prespecified analysis of the Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME 3) trial examined the impact on cardiovascular outcomes of treatment by CABG versus FFR-guided PCI in patients with three vessel disease (3-VD), stratified by acute (NSTEMI) or chronic coronary syndrome (CCS) presentation.

Which ballooning technique is best after main vessel stenting in bifurcation PCI? This two-part study compares two key approaches: PKP (POT, kissing balloon inflation, final POT) and PSP (POT, isolated side branch dilation, final POT) to determine the optimal strategy.

The TCW trial found that FFR-guided PCI with TAVI offers favorable one-year outcomes, including lower rates of all-cause mortality, MI, disabling stroke, revascularisation, valve reintervention, and severe bleeding, compared to CABG with SAVR.

The current subanalysis of the BioVasc trial offers valuable insights into the long-term effects of ICR versus SCR strategies in STEMI patients with MVD. The findings support current guidelines on the necessity of revascularizing non-culprit lesions.

The present study aimed to revise the IVUS-derived segmental MSA criteria for optimal stent expansion in patients undergoing an up-front 2-stent strategy using the crush technique for LM bifurcation lesions to predict the 5-year clinical outcomes.

In coronary bifurcation lesions (CBL) PCI, intracoronary imaging (ICI) is preferred for its superior outcomes over angiography alone, but its adoption is limited by education and technology access barriers, resulting in most CBL PCIs still using angiographic guidance only.