 
                                                                        Kalpa De Silva
Latest contributions
Effect of wire jailing at side branch in 1-stent strategy for coronary bifurcation lesions
06 May 2022
This study aimed to determine the effectiveness of jailing a wire in the side branch of a bifurcation lesion to prevent side branch compromise during provisional main vessel stenting when a one-stent in bifurcation PCI technique is adopted.

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                    Pre-treatment with P2Y12 inhibitors in patients with chronic coronary syndrome undergoing percutaneous coronary intervention: a report from the Swedish Coronary Angiography and Angioplasty Registry
11 Mar 2022
The optimal timing of the administration of P2Y12 inhibitors in patients with CCS undergoing ad-hoc PCI is unknown. This study aimed to provide observational data to clarify these quandaries.

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                    Risk of cardiovascular hospital admission after exposure to fine particulate pollution
23 Feb 2022
This current study explored the effect of heavy particle pollution on total cardiovascular admissions, whilst also looking at risk for specific cardiovascular diagnoses, such as angina, myocardial infarction, and ischaemic stroke.
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                    Influenza Vaccination after Myocardial Infarction: IAMI
24 Sep 2021
The objective of the IAMI1 trial was to determine whether early influenza vaccination reduces the risk of cardiovascular events in patients admitted with an acute-MI or high-risk stable coronary artery disease in an adequately powered randomized control trial setting.

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                    Treatment effects of Interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest: the IMICA Trial
21 Sep 2021
The IMICA trial explored the effect of a single 1-hour infusion of Tocilizumab, initiated in patients as early as feasible in their hospital admission, post-cardiac arrest, and sought to investigate whether this would reduce the systemic inflammatory response.

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                    Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis
14 Jun 2021
Read more about this systematic review and meta-analysis which looked to ascertain if there is benefit in individualizing anti-platelet therapy on the basis of the CYP2C19 genotype.
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                    External applicability of the ISCHEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease
03 Jun 2021
This study aimed to delineate the external validity of the ISCHEMIA trial by applying the ISCHEMIA inclusion and exclusion criteria to an established cohort of patients with stable coronary disease in an observational setting.
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