Kalpa De Silva

Kalpa De Silva

Interventional cardiologist / Cardiologist
Guy's and St Thomas' NHS Foundation Trust - London, United Kingdom

Latest contributions

Effect of wire jailing at side branch in 1-stent strategy for coronary bifurcation lesions

06 May 2022

This study aimed to determine the effectiveness of jailing a wire in the side branch of a bifurcation lesion to prevent side branch compromise during provisional main vessel stenting when a one-stent in bifurcation PCI technique is adopted.

Ahmed Shahin

Reviewer

Ahmed Shahin
Kalpa De Silva

Reviewer

Kalpa De Silva

Pre-treatment with P2Y12 inhibitors in patients with chronic coronary syndrome undergoing percutaneous coronary intervention: a report from the Swedish Coronary Angiography and Angioplasty Registry

11 Mar 2022

The optimal timing of the administration of P2Y12 inhibitors in patients with CCS undergoing ad-hoc PCI is unknown. This study aimed to provide observational data to clarify these quandaries.

Kalpa De Silva

Reviewer

Kalpa De Silva
Trisha Suji

Reviewer

Trisha Suji

Risk of cardiovascular hospital admission after exposure to fine particulate pollution

23 Feb 2022

This current study explored the effect of heavy particle pollution on total cardiovascular admissions, whilst also looking at risk for specific cardiovascular diagnoses, such as angina, myocardial infarction, and ischaemic stroke.

Reviewer

Bawan Abdulaziz
Kalpa De Silva

Reviewer

Kalpa De Silva

Influenza Vaccination after Myocardial Infarction: IAMI

24 Sep 2021

The objective of the IAMI1 trial was to determine whether early influenza vaccination reduces the risk of cardiovascular events in patients admitted with an acute-MI or high-risk stable coronary artery disease in an adequately powered randomized control trial setting.

Christopher Johnston

Reviewer

Christopher Johnston
Kalpa De Silva

Reviewer

Kalpa De Silva

Treatment effects of Interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest: the IMICA Trial

21 Sep 2021

The IMICA trial explored the effect of a single 1-hour infusion of Tocilizumab, initiated in patients as early as feasible in their hospital admission, post-cardiac arrest, and sought to investigate whether this would reduce the systemic inflammatory response.

Paul Hill

Reviewer

Paul Hill
Kalpa De Silva

Reviewer

Kalpa De Silva

Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y12 inhibitor therapy: a meta-analysis

14 Jun 2021

Read more about this systematic review and meta-analysis which looked to ascertain if there is benefit in individualizing anti-platelet therapy on the basis of the CYP2C19 genotype. 

Reviewer

Samuel Mcgrath
Kalpa De Silva

Reviewer

Kalpa De Silva

External applicability of the ISCHEMIA trial: an analysis of a prospective nationwide registry of patients with stable coronary artery disease

03 Jun 2021

This study aimed to delineate the external validity of the ISCHEMIA trial by applying the ISCHEMIA inclusion and exclusion criteria to an established cohort of patients with stable coronary disease in an observational setting.

Reviewer

Rupert Simpson
Kalpa De Silva

Reviewer

Kalpa De Silva