NSTEMI (Non-ST-segment elevation myocardial infarction)

Find all the latest content on NSTEMI published on this website.

NSTEMI is considered one of the leading causes of morbidity and mortality and its definition and treatment remains challenging requiring specific, adapted responses. Understanding different biomarkers, becoming aware of emerging new agents used in adjunctive pharmacotherapy, keeping abreast of advances in imaging techniques as well as the use of invasive imaging and functional assessment is critical. Tools, devices and techniques, and complications such as different types of vascular access or bleeding risks, can also be found here…

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NSTEMI

284 results

Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II)

29 Mar 2021

This is the first prospective natural history study to evaluate the utility of comprehensive intravascular imaging with both IVUS and NIRS in predicting future adverse events following acute myocardial infarction.

Tara Jones

Reviewer

Tara Jones
Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
CCT and NIRS imaging illustrating plaque consistency in a culprit lesion

High bleeding risk and clinical outcomes in East Asian patients undergoing percutaneous coronary intervention: the PENDULUM registry

25 Feb 2021

The study aimed to evaluate the validity of the Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria for East Asian patients undergoing contemporary percutaneous coronary intervention (PCI) from the PENDULUM registry.

Authors :

Masato Nakamura, Kazushige Kadota, Koichi Nakao, Yoshihisa Nakagawa, Junya Shite, Hiroyoshi Yokoi, Ken Kozuma, Kengo Tanabe, Raisuke Iijima, Atsushi Harada, Takeshi Kuroda, Yoshitaka Murakami
EuroIntervention: the PENDULUM registry

3-year outcomes of the ULTIMATE trial comparing intravascular ultrasound versus angiography-guided drug-eluting stent implantation

23 Feb 2021

ULTIMATE provides additional long-term randomised control data showing the benefit of IVUS guided PCI in an all-comers population.

Nicola Ryan

Reviewer

Nicola Ryan
ULTIMATE was a randomised control trial comparing IVUS vs DES implantation in 1,448 allcomers.

PCI optimisation in ACS patients

12 Dec 2020 – From GulfPCR-GIM 2020

Watch this session to learn through case examples how to optimise the treatment and results of ACS patients both at the short and long-term and to understand the importance of physiology assessment in ACS and the latest evidence from the field.

This session was originally presented during...

PCI optimisation in ACS patients

The EURO SHOCK Trial: Design, aims and objectives

19 Nov 2020

Randomised comparison of extra corporeal membrane oxygenation (ECMO) delivered after acute-PCI plus standard of care versus standard of care alone after acute PCI, in patients presenting with ACS and cardiogenic shock

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
The EURO SHOCK Trial: Design, aims and objectives

The impact of COVID-19 pandemic on interventional cardiologists in training

23 Oct 2020

In collaboration with EuroIntervention Journal

The authors decided to create a survey tailored for ICTs in order to assess the changes in their training. Capturing the essence of the responses may help to identify the most appropriate strategies to provide the highest standards and skills achievements in COVID-19...

The impact of COVID-19 pandemic on interventional cardiologists in training

Arterial lactate in cardiogenic shock: Prognostic value of clearance versus single values

15 Oct 2020

This subanalysis of the IABP-SHOCK study shows how a negative trial, when properly conducted, can generate useful hypothesis-generating information with relevant clinical impact. Find out more!

Luigi Biasco

Reviewer

Luigi Biasco
Arterial lactate in cardiogenic shock: Prognostic value of clearance vs single values

Coronary optical coherence tomography and cardiac magnetic resonance imaging to determine underlying causes of MINOCA in women

10 Dec 2020

The Women’s Heart Attack Research Programme was a prospective multicentre observational study using a combined imaging strategy to determine the underlying aetiology of MINOCA.

Nicola Ryan

Reviewer

Nicola Ryan
Coronary OCT and cardiac magnetic resonance imaging to determine underlying causes of MINOCA in women

Prasugrel-based de-escalation of dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome

06 Oct 2020

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Prasugrel-based de-escalation of DAPT after PCI in patients with ACS

Clinical outcomes of calcified nodules detected by optical coherence tomography: a sub-analysis of the CLIMA study

10 Sep 2020

The goal of the present post hoc analysis of the CLIMA registry was to establish the relationship between calcified nodules (CNs) with (CND) or without (CNWD) disruption of the superficial intimal fibrous layer and one-year occurrence of target lesion myocardial infarction (MI) and/or cardiac death.

Authors :

F. Prati, L. Gatto, F. Fabbiocchi, R. Vergallo, G. Paoletti, G. Ruscica, V. Marco, E. Romagnoli, A. Boi, M. Fineschi, G. Calligaris, C. Tamburino, F. Crea, Y. Ozaki, F. Alfonso, E. Arbustini
EuroIntervention - Clinical outcomes of calcified nodules detected by optical coherence tomography: a sub-analysis of the CLIMA study

Timing of oral P2Y12 inhibitor administration in non-ST elevation acute coronary syndrome

08 Sep 2020

What do you do in your daily practice: Do you use routine pre-treatment in NSTEMI patients? Have you modified your practice based on the new ESC guidelines?

Reviewer

Salvatore Brugaletta
Timing of oral P2Y12 inhibitor administration in NSTE-ACS

REALITY - A trial of transfusion strategies for myocardial infarction and anemia

03 Sep 2020

ESC Congress 2020: Tabassome Simon (Paris, France) discusses with Francesco Costa the results of REALITY trial which supports the use of a restrictive strategy for blood transfusion in MI patients with anemia.

Francesco Costa

Author

Francesco Costa
REALITY - A trial of transfusion strategies for myocardial infarction and anemia

Improving outcomes after PCI: what can interventionalists learn from the ATPCI trial?

02 Sep 2020

Professor Roberto Ferrari presented the results of the ATPCI trial on Sunday, August 30th, in a Hot Line session of the ESC Congress 2020 The Digital Experience. Dejan Milasinovic provides his analysis of this study.

Dejan Milasinovic

Author

Dejan Milasinovic
Improving outcomes after PCI: what can interventionalists learn from the ATPCI trial?

What’s new in the 2020 ESC Clinical Practice Guideline on the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (NSTE-ACS)?

29 Aug 2020

Majority of ischemic heart disease patients present with NSTEACS . Management of NSTEACS starts with correct diagnosis, appropriate timely initiation of the right pharmacotherapy, provision of coronary angiography/intervention procedures and secondary preventative care. 5 years on from the last ESC NSTEACS guidelines, what does the new...

Vijay Kunadian

Author

Vijay Kunadian
ESC NSTEACS guidelines 2020

Revascularisation strategies - PCR e-Course 2020 Hot lines

29 Jul 2020 – From PCR e-Course 2020

Watch a series of Hot Lines on revascularisation presented during the PCR e-Course 2020, followed by an analysis of the results and their impact on your practice: ISIS II, REDUCER-I, RINCAL, SYNTAX score II 2020.

Revascularisation strategies

PCR Trials: Ticagrelor versus Clopidogrel in ACS and invasive management (TICAKOREA)

24 Jul 2020

The objective of this study is to compare the safety and efficacy of ticagrelor with clopidogrel in patients with ACS.

Authors :

Park et al. Circulation. 2019;140:1865-77
PCR Trials: Ticagrelor versus Clopidogrel in ACS and invasive management (TICAKOREA)

Randomised comparison of the polymer-free biolimus-coated BioFreedom stent with the ultrathin strut biodegradable polymer sirolimus-eluting Orsiro stent in an all-comers population treated with PCI: the SORT OUT IX Trial

03 Jul 2020

While investigations testing differences in efficacy and safety between drug-eluting stents according to the characteristics of the coating – durable, bioresorbable, or polymer-free – have shown mixed results, several studies have highlighted the benefit of implanting a device with thinner strut.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
The SORT OUT IX trial

Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome : the TICO randomised clinical trial

02 Jul 2020

The outstanding results of the TICO trial have to be interpreted in light of a number of considerations and the generalisability of its results in other contexts requires further analysis.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with ACS : the TICO randomized clinical trial

Physiology or intracoronary imaging; or both? or none? - part 1

27 Jun 2020 – From PCR e-Course 2020

Watch a series of studies on physiology and intracoronary imaging presented during the PCR e-Course 2020, followed by an analysis of the results and their impact on your practice: SCAAR report, a sub-analysis of the FORZA trial, diagnostic accuracy of IVUS-based FFR.

Physiology or intracoronary imaging; or both? or none?

Aspirin vs. P2Y12 monotherapy in Onyx-1

26 Jun 2020 – From PCR e-Course 2020

Watch this session if you want to review the highlights of the Onyx ONE Month DAPT Program and to listen to commentary on the SAPT late breaker sub-analysis comparing the safety and efficacy of administering aspirin vs. P2Y12 inhibitor.

Videos included on this page: the Hot Line...

Aspirin vs. P2Y12 monotherapy in Onyx-1