NSTEMI (Non-ST-segment elevation myocardial infarction)

Find all the latest content on NSTEMI published on this website.

NSTEMI is considered one of the leading causes of morbidity and mortality and its definition and treatment remains challenging requiring specific, adapted responses. Understanding different biomarkers, becoming aware of emerging new agents used in adjunctive pharmacotherapy, keeping abreast of advances in imaging techniques as well as the use of invasive imaging and functional assessment is critical. Tools, devices and techniques, and complications such as different types of vascular access or bleeding risks, can also be found here…

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NSTEMI

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Left main and bifurcation PCI in NSTEMI

19 May 2022 – From EuroPCR 2022

View cases on OCT and jailed balloon technique, imaging-guided LMS bifurcation PCI, crossover stenting in a bifurcation coronary lesion to find out more about left main and bifurcation PCI in NSTEMI.

Left main and bifurcation PCI in NSTEMI

Managing complications during PCI for NSTEMI

19 May 2022 – From EuroPCR 2022

Watch this session to learn how to face various complications during PCI for NSTEMI thanks to a selection of cases presented at EuroPCR 2022: a inadvertent wire loss, the rescue of a ruptured radial artery with persistent bleeding,  as well as a missing/embolised fully deployed ostial RCA...

Managing complications during PCI for NSTEMI

Challenging and atypical lesions in NSTEMI

19 May 2022 – From EuroPCR 2022

Consult this session on NSTEMI to discover some challenging cases with atypical lesions, such as: a very long sequential SVG in an acute setting, a right coronary artery ostial in-stent restenosis, a severe three-vessels coronary artery disease, and more!

Challenging and atypical lesions in NSTEMI

How to deal with complications during primary PCI

19 May 2022 – From EuroPCR 2022

Watch these videos to learn more about the management of complications during primary PCI, such as coronary perforations, multiple acute-re-occlusions, stent dislodgment, acute thrombosis, and more!

How to deal with complications during primary PCI

Thinking beyond the coronary lesion in NSTEMI

19 May 2022 – From EuroPCR 2022

Thanks to these six clinical case submissions, including a case on an unusual risk factor, the impact of cigarette, malignant gastric cancer and severe coronary artery disease, you will understand how to think beyond the coronary lesion in NSTEMI.

Thinking beyond the coronary lesion in NSTEMI

PCI in acute coronary syndrome: when do we need assist device?

19 May 2022 – From EuroPCR 2022

Take the case of a 70-year-old-patient suffering obesity, DM, HTN, HLD, who presented with an anterior STEMI and shock, or the one of a 74-year-old woman with ACS and a very low ejection fraction, and get to understand when assist devices can be used.

PCI in acute coronary syndrome: when do we need assist device?

Dealing with calcified lesions: friends and enemies

19 May 2022 – From EuroPCR 2022

Learn tips and tricks when addressing calcified lesions, including the optimal application of imaging insights, IVUS-guidance for treatment of Type 3 perforation and more!

Dealing with calcified lesions: friends and enemies

Innovations in coronary physiology

18 May 2022 – From EuroPCR 2022

Watch this EuroPCR 2022 session to compare diagnostic accuracy of one versus two angiographic views, study normal and ANOCA patients, and find out more about a novel approach to manage coronary microvascular dysfunction.

Innovations in coronary physiology

EuroPCR 2022 Hotlines / Late-Breaking Trials in coronary artery disease: MASTER DAPT, CRUZ-HBR, DISCO RADIAL, and more!

17 May 2022 – From EuroPCR 2022

Find out more about various studies & registries in coronary artery disease! Abbreviated DAPT after complex PCI in high bleeding risk patients, comparing conventional and haemostatic dressings in radial access, angio-based QFR virtual PCI vs. conventional angio-guided PCI, CRUZ-HBR, CT-guided invasive coronary angiography in patients with...

EuroPCR 2022 Hotlines / Late-Breaking Trials in coronary artery disease: MASTER DAPT, CRUZ-HBR, DISCO RADIAL, and more!

When the barrier is crossed: dealing with iatrogenic dissection and perforation

17 May 2022 – From EuroPCR 2022

Consult this session to learn more about what to do when facing iatrogenic dissection and perforation, and discover some novel approaches and techniques to seal them, thanks to a selection of cases: sub-intimal stent placement after dissection, wire fracture followed by coronary dissection, and much more!

When the barrier is crossed: dealing with iatrogenic dissection and perforation

NSTEMI PCI: LIVE case from St Thomas' Hospital - London, United Kingdom

17 May 2022 – From EuroPCR 2022

Watch the case of a 65-year-old ex-smoker, male patient, with hypertension and cholesterol, who presented with chest pain at rest, symptomatic with nausea and dizziness, and find out how this NSTE-ACE patient was treated.

NSTEMI PCI: LIVE case from St Thomas' Hospital - London, United Kingdom

Repeat NSTEMI late after self-expanding TAVR

17 May 2022 – From EuroPCR 2022

Discover the case of a 79 year-old man presenting to the ER with NSTEMI and chest pain, with an history of NSTEMI with PCI and TAVR (CTO of the dominated RCA and intermediate stenosis of the proximal LAD). Angiography reveals a tight stenosis of proximal and...

Repeat NSTEMI late after self-expanding TAVR

PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients With Acute Myocardial Infarction

03 Apr 2022

Nicola Ryan provides a PICOT analysis of PACMAN AMI: a double-blind, placebo-controlled, randomized trial presented at ACC 2022 and simultaneously published in JAMA.

Nicola Ryan

Author

Nicola Ryan
PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients With Acute Myocardial Infarction: A Double-blind, Placebo-controlled, Randomized Trial

OCT conundrum during PCI

18 Mar 2022

How did one coronary lesion become three lesions by OCT?

Richard H. Sohn

Author

Richard H. Sohn
OCT conundrum during PCI

Risk of cardiovascular hospital admission after exposure to fine particulate pollution

23 Feb 2022

This current study explored the effect of heavy particle pollution on total cardiovascular admissions, whilst also looking at risk for specific cardiovascular diagnoses, such as angina, myocardial infarction, and ischaemic stroke.

Reviewer

Bawan Abdulaziz
Kalpa De Silva

Reviewer

Kalpa De Silva
Risk of cardiovascular hospital admission after exposure to fine particulate pollution

Improved 3-year cardiac survival after IVUS-guided long DES implantation: a patient-level analysis from 2 randomized trials

02 Feb 2022

This study aimed to increase the power to detect differences in patient survival (freedom from cardiac deaths) with IVUS versus angiography guidance by pooling the individual patient data from the IVUS-XPL and ULTIMATE trials.

Nicola Ryan

Reviewer

Nicola Ryan
Improved 3-year cardiac survival after IVUS-guided long DES implantation: a patient-level analysis from 2 randomized trials

Ticagrelor monotherapy after PCI in high-risk patients with prior MI: a prespecified TWILIGHT substudy

31 Jan 2022

In this prespecified subgroup analysis of the TWILIGHT trial, the authors report the impact of prior MI on treatment effects of ticagrelor monotherapy compared to ticagrelor and aspirin in patients at least three months post PCI...

Nicola Ryan

Reviewer

Nicola Ryan
Ticagrelor monotherapy after PCI in high-risk patients with prior MI: a prespecified TWILIGHT substudy

Best of #AHA21 Scientific Sessions: coronary and valvular heart disease trials

14 Nov 2021

Vijay Kunadian provides summaries of study designs and findings in Interventional Cardiology released at the 2021 virtual edition of the American Heart Association Congress. View an infographic of the AVATAR late-breaking trial by Ali Nazmi Calik.

Vijay Kunadian

Author

Vijay Kunadian
Best of #AHA21 Scientific sessions

Fractional flow reserve to guide treatment of patients with multivessel coronary artery disease - the FUTURE trial

05 Nov 2021

The FUTURE Trial is a prospective randomised, multicentre, open label superiority trial comparing an FFR guided treatment strategy to traditional angiography guided treatment strategy on clinical outcomes in an all-comer population with multivessel coronary artery disease.

Nicola Ryan

Reviewer

Nicola Ryan
Fractional flow reserve to guide treatment of patients with multivessel coronary artery disease - the FUTURE trial

iFR-SWEDEHEART: iFR vs FFR-Guided Coronary Revascularisation

04 Nov 2021

Nicola Ryan reviews the iFR Swedeheart multicenter, randomized, controlled, open-label clinical trial using the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) for enrolment randomisation and follow up. At one year follow up iFR guided revascularisation was shown to be non-inferior to FFR guided revascularisation, these results...

Nicola Ryan

Author

Nicola Ryan
iFR-SWEDEHEART: Five-Year Outcomes of a Randomized Trial of iFR-Guided vs. FFR-Guided PCI