NSTEMI (Non-ST-segment elevation myocardial infarction)

This study aimed to increase the power to detect differences in patient survival (freedom from cardiac deaths) with IVUS versus angiography guidance by pooling the individual patient data from the IVUS-XPL and ULTIMATE trials.

In this prespecified subgroup analysis of the TWILIGHT trial, the authors report the impact of prior MI on treatment effects of ticagrelor monotherapy compared to ticagrelor and aspirin in patients at least three months post PCI...

Vijay Kunadian provides summaries of study designs and findings in Interventional Cardiology released at the 2021 virtual edition of the American Heart Association Congress. View an infographic of the AVATAR late-breaking trial by Ali Nazmi Calik.

The FUTURE Trial is a prospective randomised, multicentre, open label superiority trial comparing an FFR guided treatment strategy to traditional angiography guided treatment strategy on clinical outcomes in an all-comer population with multivessel coronary artery disease.

Nicola Ryan reviews the iFR Swedeheart multicenter, randomized, controlled, open-label clinical trial using the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) for enrolment randomisation and follow up. At one year follow up iFR guided revascularisation was shown to be non-inferior to FFR guided revascularisation, these results...

There are limited data evaluating long-term outcomes of IVUS use in patients with acute myocardial infarction (AMI). The aim of this study was to examine the impact of IVUS-guided PCI on long-term clinical outcomes in patients with AMI.

To further investigate the treatment effects of ticagrelor monotherapy compared with ticagrelor plus aspirin in a contemporary HBR population, a pre-specified analysis of the TWILIGHT trial, TWILIGHT-HBR, was conducted by using the Academic Research Consortium (ARC) criteria for HBR.

Watch this session to learn more about complications of coronary perforation, thanks to a selection of two challenging cases: a percutaneous ventricular support device absorbing guidewire during STEMI PCI, as well as a guidewire-induced perforation of tortuous small distal coronary artery.

Watch this session to discover three abstracts on pharmacotherapy and vascular access: a molecular analysis of CYP2C19 alleles and clopidogrel resistance among Bangladeshi patients with ACS, a transradial vs. transfemoral approach in coronary angioplasty using rotational atherectomy, as well as a potential new interventional therapy with Phosphatidylcholine/deoxycholate to...

Thanks to this session, find out more about indications for drug-coated balloons, or, on the contrary, learn when not to use it. And through the analysis of two concrete cases, see how DCB can be an important tool to tackle increasingly complex patients and anatomies, especially...

View the complex case of this 70-year-old male patient with hypertension and diabetes who presented with chest pain and NSTEMI, which shows that, when dealing with challenging calcific disease, guide catheter extensions help improve device delivery.

The objective of the IAMI1 trial was to determine whether early influenza vaccination reduces the risk of cardiovascular events in patients admitted with an acute-MI or high-risk stable coronary artery disease in an adequately powered randomized control trial setting.

The IMICA trial explored the effect of a single 1-hour infusion of Tocilizumab, initiated in patients as early as feasible in their hospital admission, post-cardiac arrest, and sought to investigate whether this would reduce the systemic inflammatory response.

Hirotoshi Watanabe (Kyoto, Japan) presented the results of the STOPDAPT-2 ACS trial in a Hot Line session of the ESC Congress 2021. Dejan Milasinovic provides his analysis of this study.

Nicola Ryan presents a synthesis of this study which compares FFR-guided assessment of patients with chest pain with angiographic guidance alone, and which was presented by Nicholas Curzen (Southampton, USA) during the ESC Congress 2021.

Panos Xaplanteris interviews Nick Curzen about this study on FFR-guided assessment of patients with chest pain when compared with angiographic guidance alone which was presented during ESC Congress 2021.

Elad Asher analyses this study which compared the benefits of immediate coronary angiography with those of initial intensive care assessment with delayed angiography after out-of-hospital cardiac arrest. Hot Line session of the ESC Congress 2021.

Vijay Kunadian summarizes the key points of the LBT session of the ESC congress 2021 held on Sunday, 29 August focusing on the Lancet Commission to reduce the global burden of heart disease in women by 2030.

The aims of this study were to assess the use of antiplatelet drugs in medically treated spontaneous coronary artery dissection (SCAD) patients and to investigate the relationship between single (SAPT) and dual (DAPT) antiplatelet regimens and 1-year patient outcomes.

Find out more about the results of this analysis which suggest that operator experience may be an important effect modifier in ROTA-PCI.