NSTEMI (Non-ST-segment elevation myocardial infarction)

Find all the latest content on NSTEMI published on this website.

NSTEMI is considered one of the leading causes of morbidity and mortality and its definition and treatment remains challenging requiring specific, adapted responses. Understanding different biomarkers, becoming aware of emerging new agents used in adjunctive pharmacotherapy, keeping abreast of advances in imaging techniques as well as the use of invasive imaging and functional assessment is critical. Tools, devices and techniques, and complications such as different types of vascular access or bleeding risks, can also be found here…

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NSTEMI

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Impact of intravascular ultrasound on long-term clinical outcomes in patients with acute myocardial infarction

04 Nov 2021

There are limited data evaluating long-term outcomes of IVUS use in patients with acute myocardial infarction (AMI). The aim of this study was to examine the impact of IVUS-guided PCI on long-term clinical outcomes in patients with AMI.

Francesco Spione

Reviewer

Francesco Spione

Reviewer

Salvatore Brugaletta
Impact of intravascular ultrasound on long-term clinical outcomes in patients with acute myocardial infarction

Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR

28 Oct 2021

To further investigate the treatment effects of ticagrelor monotherapy compared with ticagrelor plus aspirin in a contemporary HBR population, a pre-specified analysis of the TWILIGHT trial, TWILIGHT-HBR, was conducted by using the Academic Research Consortium (ARC) criteria for HBR.

Reviewer

Ali Nazmi Calik
Elif Ilkay Yuce

Reviewer

Elif Ilkay Yuce
Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR

Cases on complications of coronary perforation: STEMI & NSTEMI

08 Oct 2021 – From AICT AsiaPCR 2021

Watch this session to learn more about complications of coronary perforation, thanks to a selection of two challenging cases: a percutaneous ventricular support device absorbing guidewire during STEMI PCI, as well as a guidewire-induced perforation of tortuous small distal coronary artery.

Cases on complications of coronary perforation: STEMI & NSTEMI

Abstracts on pharmacotherapy and vascular access

08 Oct 2021 – From AICT AsiaPCR 2021

Watch this session to discover three abstracts on pharmacotherapy and vascular access: a molecular analysis of CYP2C19 alleles and clopidogrel resistance among Bangladeshi patients with ACS, a transradial vs. transfemoral approach in coronary angioplasty using rotational atherectomy, as well as a potential new interventional therapy with Phosphatidylcholine/deoxycholate to...

Abstracts on pharmacotherapy and vascular access

Treating complex coronary lesions: right case right time Prevail™ DCB

01 Oct 2021 – From AICT-AsiaPCR 2021

Thanks to this session, find out more about indications for drug-coated balloons, or, on the contrary, learn when not to use it. And through the analysis of two concrete cases, see how DCB can be an important tool to tackle increasingly complex patients and anatomies, especially...

Treating complex coronary lesions: right case right time Prevail™ DCB

Telescope guide extension catheter in complex coronary interventions

01 Oct 2021 – From AICT-AsiaPCR 2021

View the complex case of this 70-year-old male patient with hypertension and diabetes who presented with chest pain and NSTEMI, which shows that, when dealing with challenging calcific disease, guide catheter extensions help improve device delivery.

Telescope guide extension

Influenza Vaccination after Myocardial Infarction: IAMI

24 Sep 2021

The objective of the IAMI1 trial was to determine whether early influenza vaccination reduces the risk of cardiovascular events in patients admitted with an acute-MI or high-risk stable coronary artery disease in an adequately powered randomized control trial setting.

Christopher Johnston

Reviewer

Christopher Johnston
Kalpa De Silva

Reviewer

Kalpa De Silva
Influenza Vaccination after Myocardial Infarction: IAMI

Treatment effects of Interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest: the IMICA Trial

21 Sep 2021

The IMICA trial explored the effect of a single 1-hour infusion of Tocilizumab, initiated in patients as early as feasible in their hospital admission, post-cardiac arrest, and sought to investigate whether this would reduce the systemic inflammatory response.

Paul Hill

Reviewer

Paul Hill
Kalpa De Silva

Reviewer

Kalpa De Silva
Treatment effects of Interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest: the IMICA Trial

STOPDAPT-2 ACS: exploring the limits of short DAPT

31 Aug 2021

Hirotoshi Watanabe (Kyoto, Japan) presented the results of the STOPDAPT-2 ACS trial in a Hot Line session of the ESC Congress 2021. Dejan Milasinovic provides his analysis of this study.

Dejan Milasinovic

Author

Dejan Milasinovic
ESC Congress 2021 - STOPDAPT-2 ACS: exploring the limits of short DAPT

RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?

29 Aug 2021

Nicola Ryan presents a synthesis of this study which compares FFR-guided assessment of patients with chest pain with angiographic guidance alone, and which was presented by Nicholas Curzen (Southampton, USA) during the ESC Congress 2021.

Nicola Ryan

Author

Nicola Ryan
RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?

RIPCORD 2: influence of routine pressure wire assessment on management strategy of coronary angiography for diagnosis of chest pain - interview with Nick Curzen

29 Aug 2021

Panos Xaplanteris interviews Nick Curzen about this study on FFR-guided assessment of patients with chest pain when compared with angiographic guidance alone which was presented during ESC Congress 2021.

Panagiotis Xaplanteris

Author

Panagiotis Xaplanteris

Author

Nick Curzen
ESC Congress 2021 - RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain?

TOMAHAWK: immediate angiography after out-of-hospital cardiac arrest without ST-segment elevation

29 Aug 2021

Elad Asher analyses this study which compared the benefits of immediate coronary angiography with those of initial intensive care assessment with delayed angiography after out-of-hospital cardiac arrest. Hot Line session of the ESC Congress 2021.

Elad Asher

Author

Elad Asher
TOMAHAWK: immediate angiography after out-of-hospital cardiac arrest without ST-segment elevation

The Lancet Commission to reduce global burden of cardiovascular disease in women by 2030

29 Aug 2021

Vijay Kunadian summarizes the key points of the LBT session of the ESC congress 2021 held on Sunday, 29 August focusing on the Lancet Commission to reduce the global burden of heart disease in women by 2030.

Vijay Kunadian

Author

Vijay Kunadian
ESC Congress 2021 - Global burden of cardiovascular disease in women; 20/20 vision for 2030: report of The Lancet commission

Antiplatelet therapy in patients with conservatively managed spontaneous coronary artery dissection from the multicentre DISCO registry

20 Aug 2021

The aims of this study were to assess the use of antiplatelet drugs in medically treated spontaneous coronary artery dissection (SCAD) patients and to investigate the relationship between single (SAPT) and dual (DAPT) antiplatelet regimens and 1-year patient outcomes.

Ahmet Zengin

Reviewer

Ahmet Zengin

Reviewer

Ali Nazmi Calik
Antiplatelet therapy in patients with conservatively managed spontaneous coronary artery dissection from the multicentre DISCO registry

Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database

05 Jul 2021

Find out more about the results of this analysis which suggest that operator experience may be an important effect modifier in ROTA-PCI.

Nicola Ryan

Reviewer

Nicola Ryan
Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database

Complications in complex rotational atherectomy

This session will help you get prepared if you have to become familiar with a novel way to release stuck rotational atherectomy burr, deal with severely calcified RCA including removal of a stuck Rotablator, or cope when Rotablator burr catheter entraps.

EuroPCR 2021 Complications in complex rotational atherectomy

Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial

18 Jun 2021

The HOST-EXAM trial sought to define whether, after DAPT for PCI with DES, clopidogrel monotherapy is associated with improved outcomes compared with aspirin monotherapy.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Aspirin vs clopidogrel for chronic maintenance monotherapy after PCI: HOST-EXAM trial

EuroPCR 2021 Hotlines / Late-Breaking Trials: Alster-FLX, ANGIE, COLOR, CREDENCE BRS, and P3

27 May 2021 – From EuroPCR 2021

Find out more about various studies & registries:

  • Left atrial appendage occlusion with the WATCHMAN FLX: The Alster-FLX Registry
  • Anatomical snuffbox for coronary angiography and interventions
  • Randomized comparison between Radial and Femoral Large-bore access Complex PCI
  • Experience with BRS for treatment of de novo native peripheral artery lesions
  • Clinical validation of...
EuroPCR 2021 Hotlines / Late-Breaking Trials: Alster-FLX, ANGIE, COLOR, CREDENCE BRS, and P3

EuroPCR 2021 Hotlines / Late-Breaking Trials in ACS: COOL AMI EU pivotal rial and more!

21 May 2021 – From EuroPCR 2021

Find out more about various studies & registries in ACS:

  • COOL AMI EU pivotal trial
  • Complete versus incomplete revascularization in NSTEMI patients
  • Non-hyperaemic IMRangio and long-term clinical outcome in STEMI
EuroPCR 2021 Hotlines / Late-Breaking Trials in ACS: COOL AMI EU pivotal rial and more!

Managing a patient with STEMI and bystander disease in the pandemic (Part 2) - Session with LIVE case

20 May 2021 – From EuroPCR 2021

Watch this session if you want to be updated on developments in treatment of ACS and STEMI, and to discuss diagnosis and treatment for bystander disease.

This session was originally presented during EuroPCR 2021.

Managing a patient with STEMI and bystander disease in the pandemic - Part 2