NSTEMI (Non-ST-segment elevation myocardial infarction)

Find all the latest content on NSTEMI published on this website.

NSTEMI is considered one of the leading causes of morbidity and mortality and its definition and treatment remains challenging requiring specific, adapted responses. Understanding different biomarkers, becoming aware of emerging new agents used in adjunctive pharmacotherapy, keeping abreast of advances in imaging techniques as well as the use of invasive imaging and functional assessment is critical. Tools, devices and techniques, and complications such as different types of vascular access or bleeding risks, can also be found here…

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NSTEMI

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A novel breakthrough in wrist-worn transdermal Troponin-I-Sensor assessment for acute myocardial infarction

23 Mar 2023

A transdermal-infrared spectrophotometric sensor (T-ISS) to assess troponins increase has been recently developed. This multicenter, observational study tested the feasibility of implementing this tool with machine learning analytics carried out in a cohort of patients presenting with acute coronary syndrome.

Reviewer

Salvatore Brugaletta
Giovanni Occhipinti

Reviewer

Giovanni Occhipinti
A novel breakthrough in wrist-worn transdermal Troponin-I-Sensor assessment for acute myocardial infarction

Essential drugs that every interventionalist needs to know

15 Dec 2022 – From GulfPCR-GIM 2022

In this GulfPCR-GIM 2022 session, learn about the role of PCSK9 inhibitors in ACS and post-PCI patients, the role of SGLT2 receptor blockers and GLP RAs, and the role of P2Y12 inhibitors as unique post-PCI antiplatelet agents.

Essential drugs that every interventionalist needs to know

Challenging ACS scenarios

14 Dec 2022 – From GulfPCR-GIM 2022

Topics in this GulfPCR-GIM 2022 session include the role of imaging in an unusual case of ACS in a young patient, PCI of an abnormal left coronary artery with AMI, embolisation of a thrombus in a non-culprit vessel during PCI in a late-presenting anterior STEMI, and...

Challenging ACS scenarios

First half of DK-Crush technique for bailout stenting of a true 0,0,1 bifurcation

09 Dec 2022

Stent implantation is largely debated in true 0,0,1 bifurcation lesion. This case shows bailout IVUS-guided stenting of a large diagonal branch after DEB-induced dissection, performed by employing the first half of the DK-Crush technique, thus avoiding stenting in the disease-free left anterior descending artery.

Giuseppe Andó

Author

Giuseppe Andó

Author

Marco Borgi

Author

Giulia Alagna
First half of DK-Crush technique for bailout stenting of a true 0,0,1 bifurcation

2-year outcomes of angiographic quantitative flow ratio-guided coronary interventions

23 Nov 2022

FAVOR-III China was an investigator-initiated, multicentre, randomised, blinded, sham-controlled trial comparing clinical outcomes of QFR versus angiography-guided strategies for the treatment of non-critical lesions in patients with stable or unstable angina, or MI, at least 72 hours prior to screening. The one-year results showed improved clinical...

Nicola Ryan

Reviewer

Nicola Ryan
2-year outcomes of angiographic quantitative flow ratio-guided coronary interventions

Aspirin vs Clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: the HOST-EXAM extended study

08 Nov 2022

The HOST-EXAM trial1 was a prospective, randomised, open-label trial investigating clopidogrel monotherapy versus aspirin therapy in patients undergoing PCI with DES who had completed 6-18 months of DAPT with no ischaemic or bleeding complications. At 24 months follow-up, clopidogrel monotherapy significantly reduced the risk of the...

Nicola Ryan

Reviewer

Nicola Ryan
Aspirin vs Clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: the HOST-EXAM extended study

A patient with ACS – how should I treat the left main?

31 Oct 2022

Take a virtual trip to Chennai, India for this first PCR Webinar on the Road.

A patient with ACS – how should I treat the left main?

Optical coherence tomography fractional flow reserve and cardiovascular outcomes in patients with acute coronary syndrome

18 Oct 2022

Optical Coherence Tomography fractional flow reserve (OCT-FFR) has been shown to correlate well with wire-based FFR; however, clinical outcomes based on OCT-FFR are not well defined. In this retrospective study, the authors sought to investigate the relationship between OCT-FFR and long-term clinical outcomes in ACS. 

Nicola Ryan

Reviewer

Nicola Ryan
Optical coherence tomography fractional flow reserve and cardiovascular outcomes in patients with acute coronary syndrome

Clinical cases - Coronary interventions - Session 4

07 Oct 2022 – From AICT-AsiaPCR 2022

Clinical cases - Coronary interventions - Session 5

07 Oct 2022 – From AICT-AsiaPCR 2022

Clinical cases - Coronary interventions - Session 8

07 Oct 2022 – From AICT-AsiaPCR 2022

Clinical cases - Coronary interventions - Session 1

06 Oct 2022 – From AICT-AsiaPCR 2022

Clinical cases - Coronary interventions - Session 3

06 Oct 2022 – From AICT-AsiaPCR 2022

BYPASS-CTCA: The value of computed tomography cardiac angiography in improving patient satisfaction and reducing contrast load, procedural duration and complications in patients who had previous CABG undergoing invasive coronary angiography

19 Sep 2022

Nicola Ryan provides her take on the BYPASS-CTCA Study which was presented by Daniel A. Jones at the TCT Congress 2022.

It must be understood that the paper has yet to be published for this study therefore all assumptions are based upon the presented data.

Nicola Ryan

Author

Nicola Ryan
Trial Computed Tomography Cardiac Angiography Contrast Load Procedural Duration CABG Invasive Coronary Angiography

Durable polymer vs. biodegradable polymer DES in patients with ACS undergoing complex PCI: A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial

30 Aug 2022

The HOST-REDUCE-POLYTECH-ACS trial was a randomised, parallel-group multicentre trial with a 2x2 factorial design testing two independent hypotheses, one of which was the non-inferiority of durable polymer drug-eluting stents (DP-DES) to biodegradable polymer drug-eluting stents (BP-DES) in patients with ACS. In this post-hoc analysis, the authors...

Nicola Ryan

Reviewer

Nicola Ryan
A post hoc analysis of the HOST-REDUCE-POLYTECH-ACS trial

Ticagrelor with and without aspirin in patients with a prior coronary artery bypass graft undergoing percutaneous coronary intervention: the TWILIGHT-CABG study

25 Aug 2022

In this post-hoc analysis of the TWILIGHT trial, the authors report the effects of ticagrelor monotherapy compared to ticagrelor and aspirin in patients with prior CABG at least three months post PCI with no adverse events and at least one clinical and one angiographic high-risk feature...

Nicola Ryan

Reviewer

Nicola Ryan
Ticagrelor with and without aspirin in patients with a prior coronary artery bypass graft undergoing percutaneous coronary intervention: the TWILIGHT-CABG study

How should I treat a patient at high-bleeding risk requiring complex distal Left Main PCI for ACS ?

17 Jun 2021

Discover the replay of this webinar on high bleeding risk and complex PCI, with E. Barbato, B. Chevalier, A. Chieffo and T. Cuisset

How should I treat a patient at high-bleeding risk requiring complex PCI?

How to use invasive coronary physiology in ACS patients?

23 Sep 2021

Watch the replay of this webinar on coronary physiology with F. Alfonso, T. Engstrom, T. Keeble and R. Kharbanda

How to use invasive coronary physiology in ACS patients?

Timing and predictors of definite stent thrombosis in comatose survivors of out-of-hospital cardiac arrest undergoing percutaneous coronary intervention and therapeutic hypothermia (ST-OHCA study)

09 Aug 2022

The ST-OHCA study is a single centre prospective study investigating the incidence, timing and predictors of definite stent thrombosis in comatose survivors of out-of-hospital cardiac arrest (OHCA) undergoing immediate PCI and therapeutic hypothermia.

Nicola Ryan

Reviewer

Nicola Ryan
Timing and predictors of definite stent thrombosis in comatose survivors of out-of-hospital cardiac arrest undergoing percutaneous coronary intervention and therapeutic hypothermia (ST-OHCA study)

Radial versus femoral access in ACS patients undergoing complex PCI is associated with consistent bleeding benefit and no excess of risk

18 Jul 2022

In this paper, the authors investigated the comparative efficacy and safety of TRA versus TFA in ACS patients undergoing complex PCI in the Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)-Access trial1.

Reviewer

Aaysha Cader

Reviewer

Ali Nazmi Calik
Radial versus femoral access in ACS patients undergoing complex PCI is associated with consistent bleeding benefit and no excess of risk