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FFR- and IVUS-guided PCI of a long and calcified LAD lesion - LIVE case

19 May 2026 – From EuroPCR 2026

A 71‑year‑old man with hypertension and dyslipidemia presented with CCS class II angina and three‑vessel coronary artery disease. Functional assessment included CT‑derived micro‑FFR, angiography‑based FFR, and stress myocardial scintigraphy. The only hemodynamically significant lesion was a long, calcified lesion of the LAD.

Lesion preparation was performed with...

FFR- and IVUS-guided PCI of a long and calcified LAD lesion - LIVE case

Behind standard practice: a place for DCB

19 May 2026 – From EuroPCR 2026

This session examines the role of drug-coated balloons (DCB) beyond standard practice in coronary revascularization. It includes discussions on revascularization strategies in young patients, rescue of early distal LIMA–LAD anastomosis, treatment of in-stent restenosis, stepwise complex CTO bifurcation revascularization using kissing DCBs, and management of calcified...

Identifying problems and solving complex anatomies during TAVI

19 May 2026 – From EuroPCR 2026

A comprehensive session on managing complex anatomies during Transcatheter Aortic Valve Implantation (TAVI), emphasizing risk markers for peri-operative complications and strategies to address difficult anatomical challenges. Real-world cases illustrate practical approaches and key learnings for handling intricate TAVI scenarios.

Mitral TEER beyond the routine: complex and complicated cases

19 May 2026 – From EuroPCR 2026

This session explores complex and complicated cases of mitral transcatheter edge-to-edge repair (TEER) beyond routine practice. It addresses challenges such as device failures, late complications, acute left ventricular dysfunction related to afterload changes, stepwise approaches to overcome procedural failures, rescue strategies in cardiogenic shock, and tailored...

Lessons learned to pave the way for future-proof strategies in TAVI

20 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session focuses on how current experience in transcatheter aortic valve implantation (TAVI) can be translated into more durable strategies for the future, particularly in patients with bicuspid aortic valve disease.

It provides a comprehensive overview of anatomical, clinical, and procedural considerations in this challenging...

Lessons learned to pave the way for future-proof strategies in TAVI

From access to reperfusion: a procedural deep dive into pulmonary embolism

20 May 2026 – From EuroPCR 2026

From vascular access to reperfusion strategy, managing acute pulmonary embolism requires rapid decision-making, careful patient selection and increasingly sophisticated interventional techniques.

This EuroPCR 2026 session takes a procedural deep dive into contemporary pulmonary embolism management, focusing on thrombus aspiration techniques and the evolving role of computer-assisted vacuum...

From access to reperfusion: a procedural deep dive into pulmonary embolism

Advancing mitral care with the Intrepid TMVR system

20 May 2026 – From EuroPCR 2026

This EuroPCR 2026 session explores the Intrepid transcatheter mitral valve replacement (TMVR) system and its role in expanding treatment options for patients with mitral regurgitation, including complex anatomies such as mitral annular calcification (MAC).

It highlights how the system’s design features and procedural imaging support a streamlined...

Advancing mitral care with the Intrepid TMVR system

Seeing differently, treating better: advanced imaging shaping modern structural heart practice

20 May 2026 – From EuroPCR 2026

This session explores the transformative role of advanced imaging, particularly 3D intracardiac echocardiography (ICE), in modern structural heart interventions. It provides practical insights into implementation, highlighting how these tools can enhance workflow efficiency and procedural confidence across transcatheter edge-to-edge repair (TEER), left atrial appendage (LAA) closure,...

Seeing differently, treating better: advanced imaging shaping modern structural heart practice

Interventional management of an aortic root fistula after aortic-valve endocarditis

25 Jan 2021

This is a 44-year old male patient with an aortic root fistula to the right heart after past infective aortic valve endocarditis. Interventional shunt occlusion was successfully performed using a transcatheter closure device.

Interventional aortic root fistula closure

Hybrid step-by-step approach to perform a Robotic DK Crush PCI

28 Jan 2022

View the case of this 65-year-old male patient who was staged for R-PCI of a Medina 1,1,1 distal left main lesion, and discover how the authors used a hybrid robotic and manual approach to perform a DK crush procedure using the second-generation R-PCI device.

Hybrid step-by-step approach to perform a Robotic DK Crush PCI

Mid-term echocardiographic outcomes following transapical mitral valve replacement: Updates from the Intrepid Pilot Study

19 Sep 2022

Pamela Gatto provides her take on the Intrepid Global Pilot Study which was presented by Renuka Jain at TCT Congress 2022.

Pamela Gatto

Author

Pamela Gatto
Updates from the Intrepid Pilot Study: Mid-term Echocardiographic Outcomes Following Transapical Mitral Valve Replacement

GLORIOUS - Efficacy of restrictive versus liberal oxygenation or Exenatide in patients undergoing coronary artery bypass grafting or aortic valve replacement – a randomised clinical trial

21 Nov 2024

Edoardo Zancanaro provides his take on the GLORIOUS trial presented by Sebastian Wiberg at AHA 2024 in Chicago.

Edoardo Zancanaro

Author

Edoardo Zancanaro
GLORIOUS

Coronary OCT and CMR imaging to determine sex differences in underlying causes of myocardial infarction with no obstructive coronary arteries

29 Mar 2026

Nicola Ryan provides her take on the trial evaluating multi-modality imaging to determine underlying causes of MINOCA in women and men. The trial results were presented by Harmony R. Reynolds at ACC.26 in New Orleans and simultaneously published in Circulation.

Nicola Ryan

Author

Nicola Ryan
Coronary optical coherence tomography and cardiac magnetic resonance imaging to determine sex differences in underlying causes of myocardial infarction with no obstructive coronary arteries

BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

07 Nov 2022

Nicola Ryan provides her take on the BRIGHT-4 study, which was presented during AHA 2022 in Chicago, & simultaneously published in the Lancet.

This study was a randomised control trial designed to assess if bivalirudin plus a high dose infusion for 2-4 hours post PPCI was superior to unfractionated...

Nicola Ryan

Author

Nicola Ryan
BRIGHT-4 – Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial

AIMI-HF trial - Ischemia and viability imaging in heart failure: The alternative imaging modalities in ischemic heart failure trial

05 Mar 2023

Nicola Ryan provides her take on this clinical trial presented by Lisa Mielniczuk at the American College of Cardiology Scientific Session (ACC.23/WCC) – note this analysis is based upon the presented slides alone.

Nicola Ryan

Author

Nicola Ryan
AIMI-HF trial - Ischemia and viability imaging in heart failure: The alternative imaging modalities in ischemic heart failure trial

The JenaValve Trilogy™ heart valve system in high surgical risk patients with symptomatic, severe aortic regurgitation: The ALIGN AR Trial

25 Oct 2023

Nicola Ryan provides her take on the ALIGN AR trial which was presented by Vinod H. Thourani at TCT Congress 2023. The Align AR trial is a prospective single-arm investigation device exemption study assessing the safety and efficacy of the Trilogy transcatheter heart valve system in patients with...

Nicola Ryan

Author

Nicola Ryan
Initial Outcomes of the JenaValve Trilogy Transcatheter Aortic Valve Replacement System in High-Risk Patients with Symptomatic Severe Native Aortic Regurgitation (ALIGN-AR)

NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome

02 Sep 2025

Daniele Giacoppo reports and provides his perspective on the main results of the ambitious NEOMINDSET trial, presented by Pedro Lemos from the Hospital Israelita Albert Einstein, São Paulo, Brazil, during a Late Breaking Trials session at the ESC Congress 2025 in Madrid, and simultaneously published in the New...

Daniele Giacoppo

Author

Daniele Giacoppo
NEO-MINDSET: Early withdrawal of aspirin after percutaneous coronary intervention for acute coronary syndrome
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