PCR Journal Club

In this prespecified subgroup analysis of the AFIRE trial, the authors report the outcomes of rivaroxaban monotherapy compared to rivaroxaban and an antiplatelet agent in patients with atrial fibrillation who underwent coronary stenting > 1 year prior to enrolment.

The FUTURE Trial is a prospective randomised, multicentre, open label superiority trial comparing an FFR guided treatment strategy to traditional angiography guided treatment strategy on clinical outcomes in an all-comer population with multivessel coronary artery disease.

There are limited data evaluating long-term outcomes of IVUS use in patients with acute myocardial infarction (AMI). The aim of this study was to examine the impact of IVUS-guided PCI on long-term clinical outcomes in patients with AMI.

To further investigate the treatment effects of ticagrelor monotherapy compared with ticagrelor plus aspirin in a contemporary HBR population, a pre-specified analysis of the TWILIGHT trial, TWILIGHT-HBR, was conducted by using the Academic Research Consortium (ARC) criteria for HBR.

In conducting the ACTIVATION trial, Redwood and colleagues seek to complement the existing literature with high-level evidence on whether percutaneous coronary intervention (PCI) prior to TAVR is non-inferior to conservative (no PCI) management.

An active surveillance programme was initiated by the Israeli Ministry of Health to ascertain the possible causal relationship between the vaccine and myocarditis and evaluate incidence, clinical relevance, and related outcomes.

Through this registry-based analysis, the authors sought to assess short and long-term outcomes of revascularisation in a latecomer STEMI population presenting between 12 to 48 hours of symptom onset.

According to the updated international revascularization guidelines, fractional flow reserve (FFR) and instantaneous wave-free period ratio (iFR) are proposed to dichotomize decision-making for ischemia detection in guiding percutaneous coronary intervention (PCI) of intermediate coronary stenosis.

The current meta-analysis highlights that mechanical thrombectomy with retrievable stents or aspiration catheters reduced disability and all-cause mortality at 90 days in acute anterior circulation ischaemic stroke.

Structural valve deterioration remains the Achilles heel of both SAVR and TAVI. Since indications for TAVI have expanded to low-risk patients in 2019, this clinical scenario poses a significant conundrum for physicians and surgeons, as the number of patients undergoing aortic valve interventions continues to grow...