63 results
Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial
18 Jun 2021
The HOST-EXAM trial sought to define whether, after DAPT for PCI with DES, clopidogrel monotherapy is associated with improved outcomes compared with aspirin monotherapy.
Reviewer
Intravascular lithotripsy for treatment of calcified coronary lesions: patient-level pooled analysis of the Disrupt CAD studies
11 May 2021
Using patient-level data from the Disrupt CAD I, II, III and IV trials, this pooled analysis assesses the efficacy and safety of intravascular lithotripsy in de novo calcified coronary lesions.
Reviewer
Reviewer
Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit smooth muscle cell proliferation after DES implantation in coronary artery disease: results of the PIONEER III randomized clinical trial
06 May 2021
The PIONEER III trial aims to assess the effectiveness and safety of the biodegradable-polymer sirolimus-eluting Supreme stent compared to durable-polymer everolimus-eluting stent (Xience or Promus), completely releasing the drug by 120 days.
Reviewer
Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study
29 Apr 2021
The objective of this analysis was to prospectively investigate the clinical impact of post-PCI FFR values on long-term clinical outcomes.
Reviewer
Uninterrupted oral anticoagulant therapy in patients undergoing unplanned percutaneous coronary intervention
13 Apr 2021
This large-scale analysis sought to compare interrupted and uninterrupted OAC therapy in patients taking OAC undergoing unplanned coronary angiography or PCI for suspected acute coronary syndrome.
Reviewer
Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II)
29 Mar 2021
This is the first prospective natural history study to evaluate the utility of comprehensive intravascular imaging with both IVUS and NIRS in predicting future adverse events following acute myocardial infarction.
Reviewer
Reviewer
3-year outcomes of the ULTIMATE trial comparing intravascular ultrasound versus angiography-guided drug-eluting stent implantation
23 Feb 2021
ULTIMATE provides additional long-term randomised control data showing the benefit of IVUS guided PCI in an all-comers population.
Reviewer
The EURO SHOCK Trial: Design, aims and objectives
19 Nov 2020
Randomised comparison of extra corporeal membrane oxygenation (ECMO) delivered after acute-PCI plus standard of care versus standard of care alone after acute PCI, in patients presenting with ACS and cardiogenic shock
Reviewer
Arterial lactate in cardiogenic shock: Prognostic value of clearance versus single values
15 Oct 2020
This subanalysis of the IABP-SHOCK study shows how a negative trial, when properly conducted, can generate useful hypothesis-generating information with relevant clinical impact. Find out more!
Reviewer
Coronary optical coherence tomography and cardiac magnetic resonance imaging to determine underlying causes of MINOCA in women
10 Dec 2020
The Women’s Heart Attack Research Programme was a prospective multicentre observational study using a combined imaging strategy to determine the underlying aetiology of MINOCA.
Reviewer
