63 results
Risk of cardiovascular hospital admission after exposure to fine particulate pollution
23 Feb 2022
This current study explored the effect of heavy particle pollution on total cardiovascular admissions, whilst also looking at risk for specific cardiovascular diagnoses, such as angina, myocardial infarction, and ischaemic stroke.
Reviewer
Reviewer
Improved 3-year cardiac survival after IVUS-guided long DES implantation: a patient-level analysis from 2 randomized trials
02 Feb 2022
This study aimed to increase the power to detect differences in patient survival (freedom from cardiac deaths) with IVUS versus angiography guidance by pooling the individual patient data from the IVUS-XPL and ULTIMATE trials.
Reviewer
Ticagrelor monotherapy after PCI in high-risk patients with prior MI: a prespecified TWILIGHT substudy
31 Jan 2022
In this prespecified subgroup analysis of the TWILIGHT trial, the authors report the impact of prior MI on treatment effects of ticagrelor monotherapy compared to ticagrelor and aspirin in patients at least three months post PCI...
Reviewer
Fractional flow reserve to guide treatment of patients with multivessel coronary artery disease - the FUTURE trial
05 Nov 2021
The FUTURE Trial is a prospective randomised, multicentre, open label superiority trial comparing an FFR guided treatment strategy to traditional angiography guided treatment strategy on clinical outcomes in an all-comer population with multivessel coronary artery disease.
Reviewer
Impact of intravascular ultrasound on long-term clinical outcomes in patients with acute myocardial infarction
04 Nov 2021
There are limited data evaluating long-term outcomes of IVUS use in patients with acute myocardial infarction (AMI). The aim of this study was to examine the impact of IVUS-guided PCI on long-term clinical outcomes in patients with AMI.
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Reviewer
Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR
28 Oct 2021
To further investigate the treatment effects of ticagrelor monotherapy compared with ticagrelor plus aspirin in a contemporary HBR population, a pre-specified analysis of the TWILIGHT trial, TWILIGHT-HBR, was conducted by using the Academic Research Consortium (ARC) criteria for HBR.
Reviewer
Reviewer
Influenza Vaccination after Myocardial Infarction: IAMI
24 Sep 2021
The objective of the IAMI1 trial was to determine whether early influenza vaccination reduces the risk of cardiovascular events in patients admitted with an acute-MI or high-risk stable coronary artery disease in an adequately powered randomized control trial setting.
Reviewer
Reviewer
Treatment effects of Interleukin-6 receptor antibodies for modulating the systemic inflammatory response after out-of-hospital cardiac arrest: the IMICA Trial
21 Sep 2021
The IMICA trial explored the effect of a single 1-hour infusion of Tocilizumab, initiated in patients as early as feasible in their hospital admission, post-cardiac arrest, and sought to investigate whether this would reduce the systemic inflammatory response.
Reviewer
Reviewer
Antiplatelet therapy in patients with conservatively managed spontaneous coronary artery dissection from the multicentre DISCO registry
20 Aug 2021
The aims of this study were to assess the use of antiplatelet drugs in medically treated spontaneous coronary artery dissection (SCAD) patients and to investigate the relationship between single (SAPT) and dual (DAPT) antiplatelet regimens and 1-year patient outcomes.
Reviewer
Reviewer
Operator volumes and in-hospital outcomes: an analysis of 7,740 rotational atherectomy procedures from the BCIS national database
05 Jul 2021
Find out more about the results of this analysis which suggest that operator experience may be an important effect modifier in ROTA-PCI.
Reviewer
