PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: NSTEMI

51 results

Functional or anatomical assessment of non-culprit lesions in acute myocardial infarction

06 Mar 2025

This study demonstrates that OCT-defined TCFA is a superior prognostic marker compared to μQFR for assessing NCLs in AMI patients.

Alessandro Sticchi

Reviewer

Alessandro Sticchi
Functional or anatomical assessment of non-culprit lesions in AMI

Comprehensive diagnosis in chronic coronary syndromes combining angiography and intracoronary testing: the AID-ANGIO study

18 Feb 2025

The authors hypothesized that enriching invasive coronary angiography (ICA) with an advanced invasive diagnosis (AID) strategy would increase the diagnostic yield of obstructive and non-obstructive coronary artery disease (INOCA).

Ruxandra Sava

Reviewer

Ruxandra Sava
Nicola Ryan

Reviewer

Nicola Ryan
Comprehensive diagnosis in CCS combining angiography and intracoronary testing AID-ANGIO study

Percutaneous vs. Surgical revascularization of non-ST-segment elevation myocardial infarction with multivessel disease: The SWEDEHEART registry

02 Jan 2025

This registry-based observational study compares surgical and percutaneous revascularization in patients with multivessel disease who underwent treatment for non-ST-segment elevation myocardial infarction (NSTEMI), utilizing data extracted from the SWEDEHEART registry.

Reviewer

Ali Nazmi Calik
Murat Gökalp

Reviewer

Murat Gökalp
Percutaneous vs. Surgical revascularization of NSTEMI with multivessel disease: The SWEDEHEART registry

Effect of colchicine on coronary plaque stability in acute coronary syndrome as assessed by optical coherence tomography: the COLOCT randomized clinical trial

27 Aug 2024

The rationale for this study was to provide direct evidence of colchicine's effects on plaque stabilization, particularly by assessing changes in plaque characteristics using optical coherence tomography (OCT).

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti

Reviewer

Salvatore Brugaletta
Effect of colchicine on coronary plaque stability in acute coronary syndrome as assessed by optical coherence tomography: the COLOCT randomized clinical trial

Durable-polymer versus biodegradable-polymer drug-eluting stents in acute coronary syndromes: three-year outcomes of the HOST REDUCE POLYTECH RCT Trial

20 Jun 2024

This trial found that, in ACS patients undergoing PCI, DP-DES and BP-DES had similar patient-oriented outcomes at three years, but BP-DES had higher device-oriented composite outcomes, mainly due to increased TLR risk.

Nicola Ryan

Reviewer

Nicola Ryan
Durable polymer vs biodegradable polymer DES in ACS 3 year outcomes HOST REDUCE POLYTECH RCT Trial

Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

13 Jun 2024

The results of this study show that IVUS guidance is associated with less late lumen loss compared to angiography guidance in HBR patients undergoing DCB angioplasty.

Nicola Ryan

Reviewer

Nicola Ryan
Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

One- versus three-month dual antiplatelet therapy in high bleeding risk patients undergoing percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes

03 Jun 2024

The optimal duration of short DAPT in ACS patients is unknown, therefore this analysis of the XIENCE Short DAPT programme compared the clinical outcomes of one versus three months DAPT in HBR patients with and without ACS.

Nicola Ryan

Reviewer

Nicola Ryan
One- versus three-month DAPT in HBR patients undergoing PCI for non-ST-segment elevation ACS

Medically treated nonischemic thin-cap fibroatheroma lesions versus fractional flow reserve-guided complete revascularization in diabetic patients

27 Feb 2024

This sub-analysis denotes that medically treated diabetic patients with FFR-negative, TCFA-carrying target lesions were associated with a higher rate event rate compared to angiographically similar ischemic target lesions that underwent revascularization.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Medically treated nonischemic thin-cap fibroatheroma lesions vs FFR-guided complete revascularization in diabetic patients

Guiding intervention for complex coronary lesions by optical coherence tomography or intravascular ultrasound

06 Nov 2023

The OCTIVUS trial was a prospective multicentre, open-label, randomised controlled trial comparing OCT guided PCI with IVUS guided PCI. In this pre-specified sub-study, the authors report the outcomes in patients with complex coronary lesions undergoing OCT- or IVUS-guided PCI. 

Nicola Ryan

Reviewer

Nicola Ryan
Guiding intervention for complex coronary lesions by OCT or IVUS

Clopidogrel versus aspirin monotherapy beyond 1 year after PCI: STOPDAPT-2 five-year results

03 Nov 2023

The STOPDAPT-2 trial was a multicenter, open-label, adjudicator-blinded, randomised control trial comparing clopidogrel monotherapy after one-month DAPT with aspirin monotherapy following 12-months DAPT in patients undergoing PCI with a everolimus-eluting stent...

Nicola Ryan

Reviewer

Nicola Ryan
Clopidogrel versus Aspirin Monotherapy Beyond 1 Year After PCI: STOPDAPT-2 5-Year Results