PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: NSTEMI

63 results

Durable-polymer versus biodegradable-polymer drug-eluting stents in acute coronary syndromes: three-year outcomes of the HOST REDUCE POLYTECH RCT Trial

20 Jun 2024

This trial found that, in ACS patients undergoing PCI, DP-DES and BP-DES had similar patient-oriented outcomes at three years, but BP-DES had higher device-oriented composite outcomes, mainly due to increased TLR risk.

Nicola Ryan

Reviewer

Nicola Ryan
Durable polymer vs biodegradable polymer DES in ACS 3 year outcomes HOST REDUCE POLYTECH RCT Trial

Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

13 Jun 2024

The results of this study show that IVUS guidance is associated with less late lumen loss compared to angiography guidance in HBR patients undergoing DCB angioplasty.

Nicola Ryan

Reviewer

Nicola Ryan
Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE III trial

One- versus three-month dual antiplatelet therapy in high bleeding risk patients undergoing percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes

03 Jun 2024

The optimal duration of short DAPT in ACS patients is unknown, therefore this analysis of the XIENCE Short DAPT programme compared the clinical outcomes of one versus three months DAPT in HBR patients with and without ACS.

Nicola Ryan

Reviewer

Nicola Ryan
One- versus three-month DAPT in HBR patients undergoing PCI for non-ST-segment elevation ACS

Medically treated nonischemic thin-cap fibroatheroma lesions versus fractional flow reserve-guided complete revascularization in diabetic patients

27 Feb 2024

This sub-analysis denotes that medically treated diabetic patients with FFR-negative, TCFA-carrying target lesions were associated with a higher rate event rate compared to angiographically similar ischemic target lesions that underwent revascularization.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Medically treated nonischemic thin-cap fibroatheroma lesions vs FFR-guided complete revascularization in diabetic patients

Guiding intervention for complex coronary lesions by optical coherence tomography or intravascular ultrasound

06 Nov 2023

The OCTIVUS trial was a prospective multicentre, open-label, randomised controlled trial comparing OCT guided PCI with IVUS guided PCI. In this pre-specified sub-study, the authors report the outcomes in patients with complex coronary lesions undergoing OCT- or IVUS-guided PCI. 

Nicola Ryan

Reviewer

Nicola Ryan
Guiding intervention for complex coronary lesions by OCT or IVUS

Clopidogrel versus aspirin monotherapy beyond 1 year after PCI: STOPDAPT-2 five-year results

03 Nov 2023

The STOPDAPT-2 trial was a multicenter, open-label, adjudicator-blinded, randomised control trial comparing clopidogrel monotherapy after one-month DAPT with aspirin monotherapy following 12-months DAPT in patients undergoing PCI with a everolimus-eluting stent...

Nicola Ryan

Reviewer

Nicola Ryan
Clopidogrel versus Aspirin Monotherapy Beyond 1 Year After PCI: STOPDAPT-2 5-Year Results

Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial

12 Jul 2023

This is a trial aiming to assess QFR and 3D-QCA DS% of all the non-infarct related arteries (IRA) with 3D-QCA DS% in all patients presenting with STEMI/NSTEMI and undergoing coronary angiography. 

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag

Reviewer

Jamilah AlRahimi
Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial

Percutaneous coronary intervention vs coronary artery bypass graft surgery for left main disease in patients with and without acute coronary syndromes: a pooled analysis of 4 randomized clinical trials

05 Jul 2023

This patient-level analysis of randomized trials comparing PCI vs CABG for the treatment of low-to-intermediate CAD involving the LM confirms the absence of long-term differences in mortality between revascularization techniques, regardless of the clinical presentation.

Giovanni Occhipinti

Reviewer

Giovanni Occhipinti
Daniele Giacoppo

Reviewer

Daniele Giacoppo
PCI vs CABG surgery for LM disease in patients with and without ACS: a pooled analysis of 4 randomized clinical trials

PCI or CABG for left main coronary artery disease: the SWEDEHEART registry

28 Jun 2023

While the choice between PCI and CABG for LMCA disease continues to be one of the most controversial topics, patient characteristics & comorbidities must be taken into account, as must the external validity of the results of RCTs in the real world, as the SWEDEHEART registry does.

Panagiotis Xaplanteris

Reviewer

Panagiotis Xaplanteris

Reviewer

Leonidas Koliastasis
PCI or CABG for left main coronary artery disease: the SWEDEHEART registry

Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients: the OPTICA study

24 May 2023

The aim of the current trial was to explore if direct P2Y12 inhibitor monotherapy was feasible and safe in patients with NSTEMI undergoing PCI.

Elad Asher

Reviewer

Elad Asher
Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients: the OPTICA study