PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: CTO, Stable CAD

61 results

Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis

01 Jun 2021

The value of elective coronary revascularisation plus medical therapy over medical therapy alone in managing stable patients with coronary artery disease is debated. Hence, the authors reviewed all trials comparing the two strategies in this population to appraise whether revascularisation in addition to medical therapy affects...

Elad Asher

Reviewer

Elad Asher
Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis

Kidney Transplant List Status and Outcomes in the ISCHEMIA-CKD Trial

27 May 2021

ISCHEMIA-CKD is the only contemporary randomized trial that prospectively evaluated an upfront strategy of coronary angiography and revascularization plus optimal medical therapy (OMT) compared with OMT alone in patients listed for renal transplant.

Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
Kidney Transplant List Status and Outcomes in the ISCHEMIA-CKD Trial

Intravascular lithotripsy for treatment of calcified coronary lesions: patient-level pooled analysis of the Disrupt CAD studies

11 May 2021

Using patient-level data from the Disrupt CAD I, II, III and IV trials, this pooled analysis assesses the efficacy and safety of intravascular lithotripsy in de novo calcified coronary lesions.

M. Pighi

Reviewer

Michele Pighi
Nicola Ryan

Reviewer

Nicola Ryan
IVL for treatment of CCL: patient-level pooled analysis of the Disrupt CAD studies

Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit smooth muscle cell proliferation after DES implantation in coronary artery disease: results of the PIONEER III randomized clinical trial

06 May 2021

The PIONEER III trial aims to assess the effectiveness and safety of the biodegradable-polymer sirolimus-eluting Supreme stent compared to durable-polymer everolimus-eluting stent (Xience or Promus), completely releasing the drug by 120 days.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit SMC proliferation after DES implantation in CAD: results of the PIONEER III trial

Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study

29 Apr 2021

The objective of this analysis was to prospectively investigate the clinical impact of post-PCI FFR values on long-term clinical outcomes.

M. Pighi

Reviewer

Michele Pighi
Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study

Uninterrupted oral anticoagulant therapy in patients undergoing unplanned percutaneous coronary intervention

13 Apr 2021

This large-scale analysis sought to compare interrupted and uninterrupted OAC therapy in patients taking OAC undergoing unplanned coronary angiography or PCI for suspected acute coronary syndrome.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Cumulative rate of outcomes

Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial

06 Apr 2021

The RADIAL study sought to explore the impact of prolonged occlusion flow-mediated dilatation (PO-FMD) in improving radial artery cannulation success.

Reviewer

Ali Nazmi Calik
Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial

Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II)

29 Mar 2021

This is the first prospective natural history study to evaluate the utility of comprehensive intravascular imaging with both IVUS and NIRS in predicting future adverse events following acute myocardial infarction.

Tara Jones

Reviewer

Tara Jones
Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
CCT and NIRS imaging illustrating plaque consistency in a culprit lesion

3-year outcomes of the ULTIMATE trial comparing intravascular ultrasound versus angiography-guided drug-eluting stent implantation

23 Feb 2021

ULTIMATE provides additional long-term randomised control data showing the benefit of IVUS guided PCI in an all-comers population.

Nicola Ryan

Reviewer

Nicola Ryan
ULTIMATE was a randomised control trial comparing IVUS vs DES implantation in 1,448 allcomers.

Mortality 10 years after percutaneous or surgical revascularization in patients with total coronary artery occlusions

16 Feb 2021

The proposed manuscript is an intriguing sub-analysis from the recent SYNTAX Extended Survival (SYNTAXES) study, where the Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) was investigated.

Alessandro Candreva

Reviewer

Alessandro Candreva

Reviewer

Salvatore Brugaletta
Mortality 10 years after percutaneous or surgical revascularization in patients with total coronary artery occlusions