80 results
Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit smooth muscle cell proliferation after DES implantation in coronary artery disease: results of the PIONEER III randomized clinical trial
06 May 2021
The PIONEER III trial aims to assess the effectiveness and safety of the biodegradable-polymer sirolimus-eluting Supreme stent compared to durable-polymer everolimus-eluting stent (Xience or Promus), completely releasing the drug by 120 days.

Reviewer

Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study
29 Apr 2021
The objective of this analysis was to prospectively investigate the clinical impact of post-PCI FFR values on long-term clinical outcomes.

Reviewer

Uninterrupted oral anticoagulant therapy in patients undergoing unplanned percutaneous coronary intervention
13 Apr 2021
This large-scale analysis sought to compare interrupted and uninterrupted OAC therapy in patients taking OAC undergoing unplanned coronary angiography or PCI for suspected acute coronary syndrome.

Reviewer

Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial
06 Apr 2021
The RADIAL study sought to explore the impact of prolonged occlusion flow-mediated dilatation (PO-FMD) in improving radial artery cannulation success.

Reviewer

Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II)
29 Mar 2021
This is the first prospective natural history study to evaluate the utility of comprehensive intravascular imaging with both IVUS and NIRS in predicting future adverse events following acute myocardial infarction.

Reviewer

Reviewer

3-year outcomes of the ULTIMATE trial comparing intravascular ultrasound versus angiography-guided drug-eluting stent implantation
23 Feb 2021
ULTIMATE provides additional long-term randomised control data showing the benefit of IVUS guided PCI in an all-comers population.

Reviewer

Mortality 10 years after percutaneous or surgical revascularization in patients with total coronary artery occlusions
16 Feb 2021
The proposed manuscript is an intriguing sub-analysis from the recent SYNTAX Extended Survival (SYNTAXES) study, where the Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) was investigated.

Reviewer

Reviewer

Death and myocardial infarction following initial revascularization vs optimal medical therapy in chronic coronary syndromes with myocardial ischemia
16 Feb 2021
A systematic review and meta-analysis of contemporary randomized controlled trials published in the JAHA, interpreted using a standardized two-step approach: PICOT and SWOT

Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial
27 Nov 2020
The ALPHEUS study sought to investigate whether more potent and rapid platelet inhibition properties of ticagrelor could reduce periprocedural atherothrombotic complications in chronic coronary syndrome patients undergoing high-risk PCI.

Reviewer

Initial invasive versus conservative management of stable ischemic heart disease in patients with a history of heart failure or left ventricular dysfunction
03 Dec 2020
Insights from the ISCHEMIA Trial, commented by D. Milasinovic

Reviewer
