PCR Journal Club

The PCR Journal Club provides a selection of Literature Reviews of top interventional cardiovascular journals world-wide, selected and commented by the PCR Journal Club team.

Filtered By
Topics: CTO, Stable CAD

80 results

Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit smooth muscle cell proliferation after DES implantation in coronary artery disease: results of the PIONEER III randomized clinical trial

06 May 2021

The PIONEER III trial aims to assess the effectiveness and safety of the biodegradable-polymer sirolimus-eluting Supreme stent compared to durable-polymer everolimus-eluting stent (Xience or Promus), completely releasing the drug by 120 days.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Novel Supreme DES with early synchronized antiproliferative drug delivery to inhibit SMC proliferation after DES implantation in CAD: results of the PIONEER III trial

Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study

29 Apr 2021

The objective of this analysis was to prospectively investigate the clinical impact of post-PCI FFR values on long-term clinical outcomes.

M. Pighi

Reviewer

Michele Pighi
Impact of post-stenting fractional flow reserve on long-term clinical outcomes - The FFR-SEARCH Study

Uninterrupted oral anticoagulant therapy in patients undergoing unplanned percutaneous coronary intervention

13 Apr 2021

This large-scale analysis sought to compare interrupted and uninterrupted OAC therapy in patients taking OAC undergoing unplanned coronary angiography or PCI for suspected acute coronary syndrome.

Daniele Giacoppo

Reviewer

Daniele Giacoppo
Cumulative rate of outcomes

Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial

06 Apr 2021

The RADIAL study sought to explore the impact of prolonged occlusion flow-mediated dilatation (PO-FMD) in improving radial artery cannulation success.

Reviewer

Ali Nazmi Calik
Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial

Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II)

29 Mar 2021

This is the first prospective natural history study to evaluate the utility of comprehensive intravascular imaging with both IVUS and NIRS in predicting future adverse events following acute myocardial infarction.

Tara Jones

Reviewer

Tara Jones
Dr. Mirvat Alasnag

Reviewer

Mirvat Alasnag
CCT and NIRS imaging illustrating plaque consistency in a culprit lesion

3-year outcomes of the ULTIMATE trial comparing intravascular ultrasound versus angiography-guided drug-eluting stent implantation

23 Feb 2021

ULTIMATE provides additional long-term randomised control data showing the benefit of IVUS guided PCI in an all-comers population.

Nicola Ryan

Reviewer

Nicola Ryan
ULTIMATE was a randomised control trial comparing IVUS vs DES implantation in 1,448 allcomers.

Mortality 10 years after percutaneous or surgical revascularization in patients with total coronary artery occlusions

16 Feb 2021

The proposed manuscript is an intriguing sub-analysis from the recent SYNTAX Extended Survival (SYNTAXES) study, where the Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) was investigated.

Alessandro Candreva

Reviewer

Alessandro Candreva

Reviewer

Salvatore Brugaletta
Mortality 10 years after percutaneous or surgical revascularization in patients with total coronary artery occlusions

Death and myocardial infarction following initial revascularization vs optimal medical therapy in chronic coronary syndromes with myocardial ischemia

16 Feb 2021

A systematic review and meta-analysis of contemporary randomized controlled trials published in the JAHA, interpreted using a standardized two-step approach: PICOT and SWOT

Death and myocardial infarction following initial revascularization versus optimal medical therapy in chronic coronary syndromes with myocardial ischemia

Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial

27 Nov 2020

The ALPHEUS study sought to investigate whether more potent and rapid platelet inhibition properties of ticagrelor could reduce periprocedural atherothrombotic complications in chronic coronary syndrome patients undergoing high-risk PCI.

Reviewer

Ali Nazmi Calik
Ticagrelor versus clopidogrel in elective PCI (ALPHEUS)

Initial invasive versus conservative management of stable ischemic heart disease in patients with a history of heart failure or left ventricular dysfunction

03 Dec 2020

Insights from the ISCHEMIA Trial, commented by D. Milasinovic

Dejan Milasinovic

Reviewer

Dejan Milasinovic
Initial invasive vs conservative management of stable ischemic heart disease in patients with a history of heart failure or left ventricular dysfunction