PCR Journal Club

The OCTIVUS trial was a prospective multicentre, open-label, randomised controlled trial comparing OCT guided PCI with IVUS guided PCI. In this pre-specified sub-study, the authors report the outcomes in patients with complex coronary lesions undergoing OCT- or IVUS-guided PCI. 

The STOPDAPT-2 trial was a multicenter, open-label, adjudicator-blinded, randomised control trial comparing clopidogrel monotherapy after one-month DAPT with aspirin monotherapy following 12-months DAPT in patients undergoing PCI with a everolimus-eluting stent...

This multicenter, prospective, single-arm study determined that Focal CAD had a higher plaque burden and was predominantly lipid-rich with a high prevalence of TCFA, whereas calcifications were more prevalent in diffuse CAD.

The aim of the REVASC-TAVI study was to compare different PCI timing strategies in patients with AS and significant CAD undergoing TAVI.

This is a trial aiming to assess QFR and 3D-QCA DS% of all the non-infarct related arteries (IRA) with 3D-QCA DS% in all patients presenting with STEMI/NSTEMI and undergoing coronary angiography. 

This patient-level analysis of randomized trials comparing PCI vs CABG for the treatment of low-to-intermediate CAD involving the LM confirms the absence of long-term differences in mortality between revascularization techniques, regardless of the clinical presentation.

While the choice between PCI and CABG for LMCA disease continues to be one of the most controversial topics, patient characteristics & comorbidities must be taken into account, as must the external validity of the results of RCTs in the real world, as the SWEDEHEART registry does.

This study challenges the double-jeopardy assumption as the main cause of adverse outcome in STEMI with non-IRA CTO, as a collateral origin distal from the acute IRA occlusion was associated with a significantly better prognosis than with a proximal origin.

The present study showed that compared to clopidogrel, ticagrelor and prasugrel have comparable 1-year efficacy and safety profiles in individuals with CCS undergoing PCI. 

This pilot study aimed to investigate the feasibility, safety, and efficacy (long-term patency) of the recanalization of chronic RAO via DRA7.