PCR Journal Club

The results of this sub-analysis of the ALPHEUS trial show that complex PCI criteria are present in a large percentage of patients with chronic coronary syndrome and are associated with higher rates of both periprocedural events and MACE than non-complex PCI.

The primary aim of this study was to demonstrate the superiority of physiology-guided PCI, using either angiography or microcatheter-derived FFR, over conventional angiography-based PCI in complex high-risk indicated procedures (CHIPs) in obtaining a higher FFR post-PCI.

This study aims to compare the results of EST in patients reporting angina with those having non-obstructive coronary artery disease (ANOCA), against the reference standard of microvascular function.

The OCTIVUS trial was a prospective multicentre, open-label, randomised controlled trial comparing OCT guided PCI with IVUS guided PCI. In this pre-specified sub-study, the authors report the outcomes in patients with complex coronary lesions undergoing OCT- or IVUS-guided PCI. 

The STOPDAPT-2 trial was a multicenter, open-label, adjudicator-blinded, randomised control trial comparing clopidogrel monotherapy after one-month DAPT with aspirin monotherapy following 12-months DAPT in patients undergoing PCI with a everolimus-eluting stent...

This multicenter, prospective, single-arm study determined that Focal CAD had a higher plaque burden and was predominantly lipid-rich with a high prevalence of TCFA, whereas calcifications were more prevalent in diffuse CAD.

The aim of the REVASC-TAVI study was to compare different PCI timing strategies in patients with AS and significant CAD undergoing TAVI.

This is a trial aiming to assess QFR and 3D-QCA DS% of all the non-infarct related arteries (IRA) with 3D-QCA DS% in all patients presenting with STEMI/NSTEMI and undergoing coronary angiography. 

This patient-level analysis of randomized trials comparing PCI vs CABG for the treatment of low-to-intermediate CAD involving the LM confirms the absence of long-term differences in mortality between revascularization techniques, regardless of the clinical presentation.

While the choice between PCI and CABG for LMCA disease continues to be one of the most controversial topics, patient characteristics & comorbidities must be taken into account, as must the external validity of the results of RCTs in the real world, as the SWEDEHEART registry does.